WASHC3 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	8 studies	22% ± 3%	Explore
regulatory T cell	8 studies	22% ± 3%	Explore
fibroblast	7 studies	24% ± 10%	Explore
macrophage	7 studies	23% ± 5%	Explore
oligodendrocyte	7 studies	28% ± 8%	Explore
plasma cell	6 studies	28% ± 11%	Explore
B cell	6 studies	18% ± 2%	Explore
epithelial cell	6 studies	34% ± 9%	Explore
astrocyte	6 studies	30% ± 8%	Explore
CD8-positive, alpha-beta T cell	6 studies	20% ± 5%	Explore
non-classical monocyte	5 studies	26% ± 7%	Explore
CD4-positive, alpha-beta T cell	5 studies	18% ± 3%	Explore
ciliated cell	5 studies	29% ± 5%	Explore
plasmacytoid dendritic cell	5 studies	22% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	18% ± 1%	Explore
classical monocyte	4 studies	23% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	19% ± 2%	Explore
abnormal cell	4 studies	23% ± 7%	Explore
naive B cell	4 studies	18% ± 3%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	18% ± 1%	Explore
plasmablast	3 studies	48% ± 15%	Explore
conventional dendritic cell	3 studies	32% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	17% ± 2%	Explore
exhausted T cell	3 studies	21% ± 8%	Explore
hematopoietic precursor cell	3 studies	23% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	18% ± 2%	Explore
lymphocyte	3 studies	20% ± 3%	Explore
smooth muscle cell	3 studies	18% ± 1%	Explore
Mueller cell	3 studies	20% ± 1%	Explore
memory B cell	3 studies	16% ± 0%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	20% ± 0%	Explore
GABAergic neuron	3 studies	27% ± 5%	Explore
glutamatergic neuron	3 studies	39% ± 7%	Explore
microglial cell	3 studies	22% ± 5%	Explore
oligodendrocyte precursor cell	3 studies	21% ± 5%	Explore
dendritic cell	3 studies	35% ± 4%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore
pericyte	3 studies	16% ± 0%	Explore
basal cell	3 studies	34% ± 4%	Explore
natural killer cell	3 studies	22% ± 5%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	5 studies	20% ± 4%	Explore
brain	5 studies	32% ± 7%	Explore
lung	4 studies	22% ± 9%	Explore
eye	3 studies	23% ± 5%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	1350.97	258 / 258	100%	40.19	230 / 230
esophagus	100%	1512.03	1445 / 1445	100%	22.80	183 / 183
kidney	100%	1364.47	89 / 89	100%	34.29	901 / 901
ovary	100%	1027.63	180 / 180	100%	22.24	430 / 430
prostate	100%	1321.43	245 / 245	100%	29.68	502 / 502
thymus	100%	1281.79	653 / 653	100%	32.48	605 / 605
brain	100%	1434.76	2641 / 2642	100%	35.85	705 / 705
breast	100%	1359.39	459 / 459	100%	28.78	1116 / 1118
bladder	100%	1473.52	21 / 21	100%	26.85	503 / 504
uterus	100%	1336.32	170 / 170	100%	27.09	458 / 459
stomach	100%	1033.84	359 / 359	100%	26.35	285 / 286
skin	100%	1243.78	1807 / 1809	99%	22.84	469 / 472
intestine	100%	1358.01	966 / 966	99%	26.67	523 / 527
lung	99%	1006.92	572 / 578	100%	22.78	1155 / 1155
liver	100%	644.65	225 / 226	99%	21.23	403 / 406
pancreas	95%	450.83	313 / 328	100%	26.50	178 / 178
adipose	100%	1400.52	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	34.39	29 / 29
spleen	100%	1122.95	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	25.41	45 / 45
ureter	0%	0	0 / 0	100%	23.11	1 / 1
blood vessel	100%	1623.77	1333 / 1335	0%	0	0 / 0
muscle	99%	958.30	796 / 803	0%	0	0 / 0
heart	98%	1006.43	845 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	98%	18.44	78 / 80
peripheral blood	85%	740.66	789 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0