VTI1B | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	16 studies	19% ± 4%	Explore
macrophage	15 studies	23% ± 7%	Explore
classical monocyte	12 studies	25% ± 8%	Explore
non-classical monocyte	12 studies	28% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	20% ± 4%	Explore
conventional dendritic cell	8 studies	25% ± 10%	Explore
endothelial cell	8 studies	26% ± 8%	Explore
epithelial cell	8 studies	36% ± 16%	Explore
ciliated cell	7 studies	34% ± 12%	Explore
mature NK T cell	7 studies	18% ± 1%	Explore
monocyte	7 studies	20% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	18% ± 2%	Explore
B cell	6 studies	20% ± 4%	Explore
regulatory T cell	6 studies	18% ± 2%	Explore
plasmacytoid dendritic cell	6 studies	20% ± 6%	Explore
gamma-delta T cell	6 studies	20% ± 6%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	18% ± 2%	Explore
epithelial cell of proximal tubule	5 studies	23% ± 4%	Explore
CD8-positive, alpha-beta T cell	5 studies	20% ± 4%	Explore
myeloid cell	5 studies	23% ± 10%	Explore
basal cell	5 studies	34% ± 17%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	17% ± 2%	Explore
kidney loop of Henle epithelial cell	4 studies	24% ± 3%	Explore
megakaryocyte	4 studies	27% ± 5%	Explore
fibroblast	4 studies	31% ± 12%	Explore
erythrocyte	4 studies	25% ± 15%	Explore
secretory cell	3 studies	29% ± 18%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	16% ± 0%	Explore
hematopoietic precursor cell	3 studies	20% ± 4%	Explore
abnormal cell	3 studies	18% ± 3%	Explore
extravillous trophoblast	3 studies	17% ± 1%	Explore
endothelial cell of lymphatic vessel	3 studies	20% ± 7%	Explore
retinal cone cell	3 studies	51% ± 13%	Explore
Mueller cell	3 studies	19% ± 3%	Explore
smooth muscle cell	3 studies	44% ± 38%	Explore
exhausted T cell	3 studies	17% ± 1%	Explore
intermediate monocyte	3 studies	34% ± 14%	Explore
GABAergic neuron	3 studies	32% ± 4%	Explore
glutamatergic neuron	3 studies	39% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	20% ± 2%	Explore
connective tissue cell	3 studies	19% ± 2%	Explore
enterocyte	3 studies	20% ± 3%	Explore
goblet cell	3 studies	24% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	21% ± 7%	Explore
double negative thymocyte	3 studies	21% ± 3%	Explore
platelet	3 studies	21% ± 5%	Explore
neuron	3 studies	28% ± 13%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	9 studies	20% ± 4%	Explore
lung	6 studies	29% ± 13%	Explore
brain	5 studies	26% ± 8%	Explore
kidney	4 studies	19% ± 2%	Explore
intestine	3 studies	22% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	5222.03	2642 / 2642	100%	21.44	705 / 705
breast	100%	4747.48	459 / 459	100%	21.51	1118 / 1118
esophagus	100%	3927.42	1445 / 1445	100%	22.65	183 / 183
intestine	100%	4214.64	966 / 966	100%	18.57	527 / 527
kidney	100%	5549.19	89 / 89	100%	25.37	901 / 901
lung	100%	3553.44	578 / 578	100%	17.54	1155 / 1155
ovary	100%	2980.69	180 / 180	100%	16.74	430 / 430
prostate	100%	4445.99	245 / 245	100%	26.03	502 / 502
stomach	100%	3403.47	359 / 359	100%	18.83	286 / 286
bladder	100%	4040.00	21 / 21	100%	17.60	503 / 504
skin	100%	3873.08	1809 / 1809	100%	20.79	471 / 472
uterus	100%	2612.82	170 / 170	100%	15.77	458 / 459
thymus	100%	5003.87	653 / 653	100%	20.16	603 / 605
pancreas	99%	2330.19	326 / 328	100%	18.12	178 / 178
liver	100%	2192.97	226 / 226	99%	11.79	403 / 406
adrenal gland	100%	3136.67	258 / 258	99%	20.50	228 / 230
adipose	100%	5568.49	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	15.19	29 / 29
muscle	100%	3402.21	803 / 803	0%	0	0 / 0
spleen	100%	2844.56	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	14.12	45 / 45
ureter	0%	0	0 / 0	100%	12.45	1 / 1
blood vessel	100%	3589.70	1334 / 1335	0%	0	0 / 0
peripheral blood	99%	2051.97	918 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	99%	19.47	79 / 80
heart	98%	3455.40	844 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0048280	Biological process	vesicle fusion with Golgi apparatus
GO_0061025	Biological process	membrane fusion
GO_0016236	Biological process	macroautophagy
GO_0006886	Biological process	intracellular protein transport
GO_0042147	Biological process	retrograde transport, endosome to Golgi
GO_0016192	Biological process	vesicle-mediated transport
GO_0006904	Biological process	vesicle docking involved in exocytosis
GO_0006891	Biological process	intra-Golgi vesicle-mediated transport
GO_0006896	Biological process	Golgi to vacuole transport
GO_1903076	Biological process	regulation of protein localization to plasma membrane
GO_0097352	Biological process	autophagosome maturation
GO_0031902	Cellular component	late endosome membrane
GO_0005576	Cellular component	extracellular region
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0055037	Cellular component	recycling endosome
GO_0031901	Cellular component	early endosome membrane
GO_0055038	Cellular component	recycling endosome membrane
GO_0005794	Cellular component	Golgi apparatus
GO_0043025	Cellular component	neuronal cell body
GO_0005829	Cellular component	cytosol
GO_0008021	Cellular component	synaptic vesicle
GO_0031093	Cellular component	platelet alpha granule lumen
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0012507	Cellular component	ER to Golgi transport vesicle membrane
GO_0031982	Cellular component	vesicle
GO_0031201	Cellular component	SNARE complex
GO_0005765	Cellular component	lysosomal membrane
GO_0000149	Molecular function	SNARE binding
GO_0005484	Molecular function	SNAP receptor activity
GO_0005515	Molecular function	protein binding
GO_0019869	Molecular function	chloride channel inhibitor activity

IV. Literature review

[source]

Gene name	VTI1B
Protein name	Vesicle transport through interaction with t-SNAREs 1B Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1)
Synonyms	VTI1L VTI2 VTI1 VTI1L1
Description	FUNCTION: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. .
Accessions	H0YJJ5 ENST00000556461.1 J3KMW2 G3V5I2 ENST00000554659.6 [Q9UEU0-1] Q9UEU0 ENST00000216456.6 ENST00000554636.1 H0YJL5 ENST00000555543.1

VTI1B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review