USF2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	20 studies	23% ± 6%	Explore
plasmacytoid dendritic cell	16 studies	35% ± 14%	Explore
B cell	15 studies	26% ± 12%	Explore
classical monocyte	10 studies	26% ± 15%	Explore
conventional dendritic cell	10 studies	25% ± 17%	Explore
naive B cell	8 studies	22% ± 6%	Explore
microglial cell	8 studies	24% ± 9%	Explore
endothelial cell	7 studies	26% ± 7%	Explore
natural killer cell	6 studies	24% ± 9%	Explore
non-classical monocyte	6 studies	29% ± 17%	Explore
memory B cell	6 studies	22% ± 5%	Explore
epithelial cell	6 studies	31% ± 15%	Explore
mast cell	5 studies	22% ± 4%	Explore
myeloid cell	5 studies	32% ± 13%	Explore
T cell	4 studies	20% ± 3%	Explore
monocyte	4 studies	25% ± 10%	Explore
leukocyte	4 studies	20% ± 4%	Explore
platelet	4 studies	33% ± 11%	Explore
mononuclear phagocyte	4 studies	22% ± 9%	Explore
hematopoietic precursor cell	4 studies	25% ± 11%	Explore
regulatory T cell	4 studies	20% ± 1%	Explore
glutamatergic neuron	4 studies	34% ± 15%	Explore
dendritic cell	4 studies	39% ± 27%	Explore
oligodendrocyte	4 studies	20% ± 3%	Explore
alveolar macrophage	3 studies	20% ± 2%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	21% ± 6%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	30% ± 1%	Explore
CD4-positive, alpha-beta T cell	3 studies	31% ± 10%	Explore
mature NK T cell	3 studies	22% ± 2%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	29% ± 9%	Explore
neuron	3 studies	31% ± 11%	Explore
retinal bipolar neuron	3 studies	19% ± 4%	Explore
immature B cell	3 studies	22% ± 4%	Explore
precursor B cell	3 studies	19% ± 3%	Explore
ciliated cell	3 studies	26% ± 1%	Explore
germinal center B cell	3 studies	18% ± 2%	Explore
intermediate monocyte	3 studies	33% ± 25%	Explore
innate lymphoid cell	3 studies	17% ± 1%	Explore
abnormal cell	3 studies	21% ± 4%	Explore
enteroendocrine cell	3 studies	28% ± 8%	Explore
basal cell	3 studies	26% ± 7%	Explore
goblet cell	3 studies	18% ± 1%	Explore
oligodendrocyte precursor cell	3 studies	21% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	6 studies	27% ± 6%	Explore
lung	5 studies	23% ± 9%	Explore
peripheral blood	5 studies	31% ± 13%	Explore
liver	4 studies	19% ± 4%	Explore
intestine	3 studies	20% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	11562.93	2642 / 2642	100%	118.22	705 / 705
esophagus	100%	7049.98	1445 / 1445	100%	59.58	183 / 183
liver	100%	7114.72	226 / 226	100%	62.81	406 / 406
ovary	100%	11095.62	180 / 180	100%	110.29	430 / 430
pancreas	100%	4416.66	328 / 328	100%	78.62	178 / 178
skin	100%	7163.59	1809 / 1809	100%	132.55	472 / 472
thymus	100%	9841.43	653 / 653	100%	103.20	605 / 605
prostate	100%	7751.58	245 / 245	100%	81.98	501 / 502
uterus	100%	8477.06	170 / 170	100%	91.34	458 / 459
stomach	100%	5821.92	359 / 359	100%	60.81	285 / 286
adrenal gland	100%	8591.12	258 / 258	100%	98.55	229 / 230
kidney	100%	6372.45	89 / 89	100%	70.69	897 / 901
lung	100%	7479.31	578 / 578	99%	72.93	1149 / 1155
breast	100%	7786.39	459 / 459	99%	87.01	1112 / 1118
intestine	100%	7731.55	966 / 966	99%	61.97	524 / 527
bladder	100%	7135.33	21 / 21	99%	79.24	501 / 504
adipose	100%	8068.83	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	179.53	80 / 80
lymph node	0%	0	0 / 0	100%	121.76	29 / 29
muscle	100%	9719.64	803 / 803	0%	0	0 / 0
spleen	100%	11855.31	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	80.47	45 / 45
ureter	0%	0	0 / 0	100%	79.83	1 / 1
heart	100%	8709.16	860 / 861	0%	0	0 / 0
blood vessel	100%	7245.69	1333 / 1335	0%	0	0 / 0
peripheral blood	100%	8942.63	926 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0000430	Biological process	regulation of transcription from RNA polymerase II promoter by glucose
GO_0000432	Biological process	positive regulation of transcription from RNA polymerase II promoter by glucose
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0055088	Biological process	lipid homeostasis
GO_0007595	Biological process	lactation
GO_0019086	Biological process	late viral transcription
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005654	Cellular component	nucleoplasm
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0042803	Molecular function	protein homodimerization activity
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0043425	Molecular function	bHLH transcription factor binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0043565	Molecular function	sequence-specific DNA binding
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding
GO_0003700	Molecular function	DNA-binding transcription factor activity
GO_0046982	Molecular function	protein heterodimerization activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	USF2
Protein name	Upstream transcription factor 2, c-fos interacting (cDNA FLJ60670, highly similar to Upstream stimulatory factor 2) Upstream stimulatory factor 2 (Class B basic helix-loop-helix protein 12) (bHLHb12) (FOS-interacting protein) (FIP) (Major late transcription factor 2) (Upstream transcription factor 2) Upstream transcription factor 2, c-fos interacting
Synonyms	BHLHB12
Description	FUNCTION: Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
Accessions	B4DLJ1 M0QZ39 ENST00000379134.7 [Q15853-4] ENST00000596380.5 ENST00000595068.5 [Q15853-2] ENST00000594064.5 ENST00000599471.5 ENST00000222305.8 [Q15853-1] ENST00000343550.9 [Q15853-3] M0QY46 M0R1C6 ENST00000602164.5 Q15853 ENST00000599625.1 V9GYR5 M0QXT0 ENST00000598058.1 ENST00000597671.5 M0QYU7

USF2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review