UBE2J1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	32 studies	32% ± 15%	Explore
endothelial cell	32 studies	29% ± 12%	Explore
plasma cell	27 studies	58% ± 22%	Explore
classical monocyte	21 studies	31% ± 15%	Explore
non-classical monocyte	21 studies	41% ± 17%	Explore
plasmacytoid dendritic cell	21 studies	55% ± 18%	Explore
memory B cell	18 studies	36% ± 10%	Explore
monocyte	16 studies	26% ± 8%	Explore
naive B cell	16 studies	28% ± 9%	Explore
conventional dendritic cell	15 studies	30% ± 17%	Explore
endothelial cell of lymphatic vessel	13 studies	21% ± 5%	Explore
macrophage	13 studies	22% ± 5%	Explore
plasmablast	12 studies	74% ± 20%	Explore
capillary endothelial cell	12 studies	22% ± 6%	Explore
natural killer cell	12 studies	24% ± 5%	Explore
pericyte	11 studies	23% ± 9%	Explore
fibroblast	11 studies	21% ± 6%	Explore
endothelial cell of artery	10 studies	26% ± 7%	Explore
gamma-delta T cell	10 studies	24% ± 9%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	25% ± 6%	Explore
IgA plasma cell	9 studies	61% ± 23%	Explore
IgG plasma cell	9 studies	53% ± 22%	Explore
endothelial cell of vascular tree	9 studies	32% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	26% ± 7%	Explore
regulatory T cell	8 studies	20% ± 3%	Explore
epithelial cell	8 studies	33% ± 15%	Explore
vein endothelial cell	7 studies	23% ± 9%	Explore
CD8-positive, alpha-beta T cell	7 studies	21% ± 4%	Explore
mucosal invariant T cell	7 studies	20% ± 4%	Explore
precursor B cell	7 studies	50% ± 17%	Explore
mature NK T cell	6 studies	20% ± 3%	Explore
myofibroblast cell	6 studies	19% ± 2%	Explore
smooth muscle cell	6 studies	22% ± 5%	Explore
dendritic cell	6 studies	39% ± 19%	Explore
connective tissue cell	6 studies	21% ± 5%	Explore
myeloid cell	6 studies	34% ± 16%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	23% ± 7%	Explore
hematopoietic precursor cell	5 studies	34% ± 12%	Explore
platelet	5 studies	23% ± 4%	Explore
CD4-positive, alpha-beta T cell	5 studies	24% ± 7%	Explore
pro-B cell	5 studies	44% ± 9%	Explore
immature B cell	5 studies	49% ± 10%	Explore
abnormal cell	5 studies	28% ± 13%	Explore
goblet cell	5 studies	27% ± 10%	Explore
T cell	5 studies	22% ± 7%	Explore
pancreatic A cell	4 studies	36% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	21% ± 2%	Explore
hematopoietic stem cell	4 studies	25% ± 4%	Explore
lymphocyte	4 studies	22% ± 4%	Explore
megakaryocyte	4 studies	34% ± 7%	Explore
basal cell	4 studies	25% ± 8%	Explore
secretory cell	4 studies	24% ± 9%	Explore
germinal center B cell	4 studies	54% ± 17%	Explore
innate lymphoid cell	4 studies	23% ± 4%	Explore
IgM plasma cell	4 studies	50% ± 21%	Explore
astrocyte	4 studies	22% ± 5%	Explore
glutamatergic neuron	4 studies	39% ± 13%	Explore
enteroendocrine cell	4 studies	25% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	21% ± 3%	Explore
squamous epithelial cell	3 studies	38% ± 21%	Explore
type B pancreatic cell	3 studies	35% ± 12%	Explore
mononuclear phagocyte	3 studies	30% ± 8%	Explore
glomerular endothelial cell	3 studies	26% ± 4%	Explore
microglial cell	3 studies	24% ± 4%	Explore
ciliated cell	3 studies	32% ± 7%	Explore
intermediate monocyte	3 studies	49% ± 19%	Explore
GABAergic neuron	3 studies	37% ± 7%	Explore
oligodendrocyte precursor cell	3 studies	26% ± 4%	Explore
group 3 innate lymphoid cell	3 studies	30% ± 8%	Explore
interneuron	3 studies	33% ± 14%	Explore
neuron	3 studies	31% ± 8%	Explore
oligodendrocyte	3 studies	19% ± 2%	Explore
erythrocyte	3 studies	23% ± 6%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	13 studies	26% ± 11%	Explore
lung	7 studies	25% ± 8%	Explore
intestine	6 studies	24% ± 9%	Explore
bone marrow	5 studies	29% ± 13%	Explore
brain	5 studies	31% ± 8%	Explore
pancreas	4 studies	32% ± 14%	Explore
lymph node	3 studies	22% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	3855.33	459 / 459	100%	80.54	1118 / 1118
esophagus	100%	3290.63	1445 / 1445	100%	70.30	183 / 183
intestine	100%	4218.27	966 / 966	100%	75.97	527 / 527
ovary	100%	3343.14	180 / 180	100%	56.19	430 / 430
pancreas	100%	3529.48	328 / 328	100%	57.69	178 / 178
prostate	100%	4522.21	245 / 245	100%	148.39	502 / 502
stomach	100%	3080.60	359 / 359	100%	80.07	286 / 286
uterus	100%	3830.76	170 / 170	100%	56.56	459 / 459
lung	100%	4496.68	578 / 578	100%	74.00	1154 / 1155
thymus	100%	3705.33	653 / 653	100%	75.97	604 / 605
bladder	100%	3280.62	21 / 21	100%	56.10	503 / 504
brain	100%	2462.03	2631 / 2642	100%	62.64	705 / 705
skin	100%	3285.57	1805 / 1809	98%	67.99	464 / 472
kidney	100%	2883.56	89 / 89	97%	61.20	875 / 901
adrenal gland	100%	3520.16	258 / 258	96%	46.67	221 / 230
liver	100%	2084.35	226 / 226	96%	32.52	390 / 406
adipose	100%	4071.42	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	171.68	29 / 29
spleen	100%	6677.38	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	63.12	45 / 45
ureter	0%	0	0 / 0	100%	12.62	1 / 1
blood vessel	100%	3269.51	1333 / 1335	0%	0	0 / 0
peripheral blood	99%	9092.45	922 / 929	0%	0	0 / 0
heart	98%	1697.40	844 / 861	0%	0	0 / 0
muscle	98%	1452.28	786 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	93%	36.81	74 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_1904153	Biological process	negative regulation of retrograde protein transport, ER to cytosol
GO_0032680	Biological process	regulation of tumor necrosis factor production
GO_0018279	Biological process	protein N-linked glycosylation via asparagine
GO_0010935	Biological process	regulation of macrophage cytokine production
GO_0000209	Biological process	protein polyubiquitination
GO_0036503	Biological process	ERAD pathway
GO_0007286	Biological process	spermatid development
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0005634	Cellular component	nucleus
GO_0061631	Molecular function	ubiquitin conjugating enzyme activity
GO_0031625	Molecular function	ubiquitin protein ligase binding
GO_0005515	Molecular function	protein binding
GO_0005524	Molecular function	ATP binding

IV. Literature review

[source]

Gene name	UBE2J1
Protein name	Ubiquitin-conjugating enzyme E2 J1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J1) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE-1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HsUBC6e)
Synonyms	CGI-76 HSPC205 HSPC153 NCUBE1
Description	FUNCTION: Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD) and is essential for cells to recover from ER stress . Plays a role in MAPKAPK2-dependent translational control of TNF-alpha synthesis . Acts also as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQSTM1 through interaction with the E3 ubiquitin-protein ligase RNF26 . Plays a role in male fecundity through the interaction with the E3 ubiquitin-protein ligase RNF133 . .; FUNCTION: (Microbial infection) Promotes Dengue virus RNA replication by negatively regulating IFN-beta signaling and mediating 'Lys-48'-linked ubiquitination on IRF3 . .
Accessions	ENST00000435041.3 Q9Y385

UBE2J1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review