Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| mast cell | 20 studies | 28% ± 9% | |
| astrocyte | 17 studies | 38% ± 20% | |
| endothelial cell | 16 studies | 28% ± 11% | |
| oligodendrocyte precursor cell | 11 studies | 35% ± 16% | |
| oligodendrocyte | 11 studies | 36% ± 12% | |
| adipocyte | 9 studies | 29% ± 10% | |
| fibroblast | 9 studies | 26% ± 10% | |
| glutamatergic neuron | 8 studies | 45% ± 26% | |
| microglial cell | 8 studies | 24% ± 7% | |
| GABAergic neuron | 7 studies | 46% ± 24% | |
| interneuron | 6 studies | 41% ± 24% | |
| epithelial cell | 6 studies | 32% ± 17% | |
| macrophage | 5 studies | 29% ± 5% | |
| cardiac muscle cell | 5 studies | 41% ± 10% | |
| endothelial cell of lymphatic vessel | 5 studies | 31% ± 7% | |
| type I pneumocyte | 5 studies | 22% ± 7% | |
| type II pneumocyte | 5 studies | 19% ± 6% | |
| neuron | 4 studies | 37% ± 18% | |
| ciliated cell | 4 studies | 23% ± 7% | |
| smooth muscle cell | 4 studies | 23% ± 3% | |
| GABAergic interneuron | 3 studies | 23% ± 3% | |
| glial cell | 3 studies | 19% ± 3% | |
| retinal rod cell | 3 studies | 16% ± 0% | |
| hepatocyte | 3 studies | 28% ± 7% | |
| retinal pigment epithelial cell | 3 studies | 34% ± 17% | |
| ependymal cell | 3 studies | 45% ± 14% | |
| T cell | 3 studies | 19% ± 1% | |
| alveolar macrophage | 3 studies | 22% ± 4% | |
| monocyte | 3 studies | 21% ± 4% | |
| lymphocyte | 3 studies | 23% ± 8% | |
| basal cell | 3 studies | 32% ± 20% | |
| goblet cell | 3 studies | 31% ± 18% | |
| pericyte | 3 studies | 25% ± 4% | |
| transit amplifying cell | 3 studies | 31% ± 22% | |
| mesothelial cell | 3 studies | 32% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 1152.87 | 459 / 459 | 100% | 11.23 | 1118 / 1118 |
| pancreas | 100% | 969.09 | 328 / 328 | 100% | 8.83 | 178 / 178 |
| thymus | 100% | 1259.13 | 653 / 653 | 100% | 11.07 | 605 / 605 |
| brain | 100% | 860.22 | 2640 / 2642 | 100% | 8.72 | 705 / 705 |
| prostate | 100% | 1280.22 | 245 / 245 | 100% | 9.08 | 501 / 502 |
| kidney | 100% | 1160.02 | 89 / 89 | 100% | 11.79 | 897 / 901 |
| esophagus | 100% | 1089.23 | 1445 / 1445 | 99% | 7.39 | 182 / 183 |
| bladder | 100% | 1166.62 | 21 / 21 | 99% | 7.88 | 501 / 504 |
| lung | 100% | 1157.87 | 577 / 578 | 100% | 6.98 | 1150 / 1155 |
| adrenal gland | 100% | 963.75 | 258 / 258 | 99% | 6.27 | 227 / 230 |
| uterus | 100% | 1330.45 | 170 / 170 | 99% | 8.05 | 453 / 459 |
| intestine | 100% | 1083.06 | 966 / 966 | 99% | 9.25 | 520 / 527 |
| skin | 100% | 1020.66 | 1808 / 1809 | 98% | 23.54 | 463 / 472 |
| stomach | 100% | 954.86 | 359 / 359 | 98% | 8.58 | 279 / 286 |
| ovary | 100% | 1430.33 | 180 / 180 | 97% | 4.81 | 415 / 430 |
| liver | 100% | 512.81 | 226 / 226 | 96% | 4.62 | 388 / 406 |
| adipose | 100% | 1188.71 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 964.31 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 28.80 | 80 / 80 |
| muscle | 100% | 1187.32 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1001.18 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 5.77 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.20 | 1 / 1 |
| heart | 99% | 834.00 | 856 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 7.59 | 28 / 29 |
| peripheral blood | 68% | 433.28 | 636 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006325 | Biological process | chromatin organization |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0035145 | Cellular component | exon-exon junction complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005634 | Cellular component | nucleus |
| GO_0035064 | Molecular function | methylated histone binding |
| GO_0003713 | Molecular function | transcription coactivator activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0003682 | Molecular function | chromatin binding |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | TDRD3 |
| Protein name | Tudor domain-containing protein 3 Tudor domain containing 3 |
| Synonyms | |
| Description | FUNCTION: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins . Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci . In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1 . . |
| Accessions | B1AMN9 ENST00000196169.7 [Q9H7E2-1] F2Z2Y2 ENST00000621840.4 [Q9H7E2-2] ENST00000377882.7 ENST00000377894.6 [Q9H7E2-1] ENST00000377881.8 [Q9H7E2-3] ENST00000648252.1 [Q9H7E2-1] ENST00000484389.6 Q9H7E2 |