Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 43 studies | 31% ± 12% | |
B cell | 39 studies | 41% ± 10% | |
macrophage | 24 studies | 26% ± 11% | |
mast cell | 20 studies | 27% ± 9% | |
memory B cell | 20 studies | 45% ± 8% | |
naive B cell | 20 studies | 41% ± 9% | |
capillary endothelial cell | 13 studies | 26% ± 13% | |
endothelial cell of vascular tree | 13 studies | 42% ± 15% | |
endothelial cell of artery | 12 studies | 35% ± 13% | |
microglial cell | 11 studies | 35% ± 14% | |
non-classical monocyte | 10 studies | 23% ± 8% | |
vein endothelial cell | 10 studies | 39% ± 20% | |
myeloid cell | 9 studies | 27% ± 7% | |
endothelial cell of lymphatic vessel | 8 studies | 23% ± 6% | |
type I pneumocyte | 8 studies | 28% ± 8% | |
pericyte | 8 studies | 23% ± 9% | |
dendritic cell | 8 studies | 27% ± 10% | |
smooth muscle cell | 6 studies | 18% ± 2% | |
classical monocyte | 6 studies | 22% ± 4% | |
conventional dendritic cell | 6 studies | 22% ± 6% | |
monocyte | 6 studies | 22% ± 6% | |
epithelial cell | 5 studies | 41% ± 17% | |
club cell | 5 studies | 19% ± 4% | |
immature B cell | 5 studies | 46% ± 4% | |
basal cell | 5 studies | 29% ± 15% | |
astrocyte | 5 studies | 24% ± 9% | |
precursor B cell | 4 studies | 30% ± 9% | |
fibroblast | 4 studies | 17% ± 1% | |
ciliated cell | 4 studies | 27% ± 12% | |
germinal center B cell | 4 studies | 43% ± 18% | |
squamous epithelial cell | 3 studies | 40% ± 22% | |
plasmablast | 3 studies | 23% ± 6% | |
glomerular endothelial cell | 3 studies | 32% ± 2% | |
plasma cell | 3 studies | 27% ± 7% | |
respiratory goblet cell | 3 studies | 21% ± 6% | |
secretory cell | 3 studies | 32% ± 15% | |
GABAergic neuron | 3 studies | 28% ± 8% | |
glutamatergic neuron | 3 studies | 31% ± 12% | |
oligodendrocyte precursor cell | 3 studies | 23% ± 5% | |
abnormal cell | 3 studies | 35% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3655.64 | 1445 / 1445 | 100% | 31.21 | 183 / 183 |
lung | 100% | 6092.32 | 578 / 578 | 100% | 35.07 | 1153 / 1155 |
breast | 100% | 7945.16 | 459 / 459 | 100% | 43.72 | 1113 / 1118 |
thymus | 100% | 4955.74 | 653 / 653 | 99% | 41.25 | 600 / 605 |
bladder | 100% | 4345.81 | 21 / 21 | 99% | 25.31 | 497 / 504 |
skin | 100% | 6407.23 | 1808 / 1809 | 98% | 58.42 | 463 / 472 |
uterus | 100% | 4514.53 | 170 / 170 | 98% | 25.18 | 448 / 459 |
prostate | 100% | 3167.28 | 244 / 245 | 98% | 23.83 | 490 / 502 |
kidney | 100% | 2823.52 | 89 / 89 | 97% | 37.21 | 870 / 901 |
intestine | 100% | 3783.20 | 966 / 966 | 96% | 19.90 | 507 / 527 |
ovary | 99% | 2256.74 | 178 / 180 | 93% | 13.15 | 401 / 430 |
stomach | 93% | 2195.25 | 334 / 359 | 96% | 20.34 | 274 / 286 |
adrenal gland | 94% | 1811.26 | 243 / 258 | 85% | 14.79 | 195 / 230 |
pancreas | 76% | 1144.67 | 249 / 328 | 98% | 30.63 | 174 / 178 |
brain | 78% | 1467.05 | 2062 / 2642 | 90% | 17.97 | 635 / 705 |
adipose | 100% | 9171.51 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 5697.20 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 60.97 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 125.25 | 29 / 29 |
spleen | 100% | 8107.20 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 35.92 | 1 / 1 |
tonsil | 0% | 0 | 0 / 0 | 98% | 34.99 | 44 / 45 |
heart | 95% | 2224.69 | 822 / 861 | 0% | 0 | 0 / 0 |
liver | 19% | 242.82 | 44 / 226 | 74% | 11.33 | 300 / 406 |
muscle | 74% | 1178.62 | 592 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 65% | 3368.77 | 603 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0060754 | Biological process | positive regulation of mast cell chemotaxis |
GO_0032233 | Biological process | positive regulation of actin filament bundle assembly |
GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
GO_0032880 | Biological process | regulation of protein localization |
GO_1902309 | Biological process | negative regulation of peptidyl-serine dephosphorylation |
GO_0051017 | Biological process | actin filament bundle assembly |
GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
GO_0033633 | Biological process | negative regulation of cell-cell adhesion mediated by integrin |
GO_0045190 | Biological process | isotype switching |
GO_0030835 | Biological process | negative regulation of actin filament depolymerization |
GO_0005886 | Cellular component | plasma membrane |
GO_0098794 | Cellular component | postsynapse |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0030027 | Cellular component | lamellipodium |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0045296 | Molecular function | cadherin binding |
GO_0005524 | Molecular function | ATP binding |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | SWAP70 |
Protein name | SWAP-70 protein, isoform CRA_b (cDNA FLJ39540 fis, clone PUAEN2008314, highly similar to Switch-associated protein 70) Switch-associated protein 70 (SWAP-70) Switching B cell complex subunit SWAP70 |
Synonyms | hCG_23993 KIAA0640 HSPC321 |
Description | FUNCTION: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity). . |
Accessions | ENST00000318950.11 ENST00000526358.5 B3KUB9 E7EMB1 E9PJK8 E9PJM7 H0YDK5 ENST00000534662.1 Q9UH65 ENST00000447399.6 ENST00000534562.1 |