Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte precursor cell | 14 studies | 35% ± 18% | |
oligodendrocyte | 10 studies | 33% ± 12% | |
glial cell | 4 studies | 31% ± 16% | |
melanocyte | 3 studies | 43% ± 15% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 3 studies | 31% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
eye | 0% | 0 | 0 / 0 | 100% | 765.05 | 80 / 80 |
skin | 0% | 0 | 0 / 0 | 97% | 565.72 | 459 / 472 |
brain | 0% | 0 | 0 / 0 | 82% | 65.38 | 576 / 705 |
breast | 0% | 0 | 0 / 0 | 36% | 27.69 | 406 / 1118 |
adrenal gland | 0% | 0 | 0 / 0 | 15% | 2.46 | 35 / 230 |
pancreas | 0% | 0 | 0 / 0 | 11% | 1.29 | 19 / 178 |
esophagus | 0% | 0 | 0 / 0 | 5% | 4.33 | 10 / 183 |
stomach | 0% | 0 | 0 / 0 | 5% | 1.96 | 15 / 286 |
lung | 0% | 0 | 0 / 0 | 2% | 1.10 | 27 / 1155 |
tonsil | 0% | 0 | 0 / 0 | 2% | 5.47 | 1 / 45 |
prostate | 0% | 0 | 0 / 0 | 2% | 0.15 | 8 / 502 |
intestine | 0% | 0 | 0 / 0 | 2% | 0.13 | 8 / 527 |
uterus | 0% | 0 | 0 / 0 | 1% | 0.17 | 3 / 459 |
bladder | 0% | 0 | 0 / 0 | 1% | 0.08 | 3 / 504 |
thymus | 0% | 0 | 0 / 0 | 0% | 0.01 | 1 / 605 |
kidney | 0% | 0 | 0 / 0 | 0% | 0.01 | 1 / 901 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
adipose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 406 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
muscle | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ovary | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 430 |
peripheral blood | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0002052 | Biological process | positive regulation of neuroblast proliferation |
GO_0014003 | Biological process | oligodendrocyte development |
GO_0071466 | Biological process | cellular response to xenobiotic stimulus |
GO_0002009 | Biological process | morphogenesis of an epithelium |
GO_0001701 | Biological process | in utero embryonic development |
GO_0001755 | Biological process | neural crest cell migration |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0032808 | Biological process | lacrimal gland development |
GO_0071393 | Biological process | cellular response to progesterone stimulus |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0006368 | Biological process | transcription elongation by RNA polymerase II |
GO_0010626 | Biological process | negative regulation of Schwann cell proliferation |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
GO_0022010 | Biological process | central nervous system myelination |
GO_0030318 | Biological process | melanocyte differentiation |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0007422 | Biological process | peripheral nervous system development |
GO_0014015 | Biological process | positive regulation of gliogenesis |
GO_0048709 | Biological process | oligodendrocyte differentiation |
GO_0009653 | Biological process | anatomical structure morphogenesis |
GO_0048589 | Biological process | developmental growth |
GO_0031643 | Biological process | positive regulation of myelination |
GO_0048469 | Biological process | cell maturation |
GO_0048546 | Biological process | digestive tract morphogenesis |
GO_0061138 | Biological process | morphogenesis of a branching epithelium |
GO_0048484 | Biological process | enteric nervous system development |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0007405 | Biological process | neuroblast proliferation |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005741 | Cellular component | mitochondrial outer membrane |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_1990841 | Molecular function | promoter-specific chromatin binding |
GO_0140297 | Molecular function | DNA-binding transcription factor binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0000976 | Molecular function | transcription cis-regulatory region binding |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0001216 | Molecular function | DNA-binding transcription activator activity |
GO_0005515 | Molecular function | protein binding |
Gene name | SOX10 |
Protein name | SRY-box transcription factor 10 Transcription factor SOX-10 |
Synonyms | |
Description | FUNCTION: Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 . Transcriptional activator of MBP, via binding to the gene promoter (By similarity). . |
Accessions | ENST00000427770.1 P56693 A0A494C0R1 ENST00000651746.1 A0A8V8TM01 ENST00000396884.8 [P56693-1] A6PVD3 A0A8I5KW15 ENST00000360880.6 [P56693-1] ENST00000446929.5 H0Y5N4 ENST00000690831.1 ENST00000698177.1 |