Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 30 studies | 31% ± 16% | |
fibroblast | 28 studies | 30% ± 14% | |
macrophage | 25 studies | 38% ± 17% | |
B cell | 21 studies | 29% ± 10% | |
plasmacytoid dendritic cell | 17 studies | 37% ± 14% | |
regulatory T cell | 17 studies | 29% ± 11% | |
dendritic cell | 14 studies | 32% ± 13% | |
astrocyte | 13 studies | 30% ± 16% | |
oligodendrocyte | 13 studies | 41% ± 15% | |
naive B cell | 12 studies | 32% ± 19% | |
non-classical monocyte | 12 studies | 26% ± 9% | |
CD4-positive, alpha-beta T cell | 12 studies | 20% ± 5% | |
myeloid cell | 11 studies | 34% ± 13% | |
monocyte | 10 studies | 24% ± 8% | |
pericyte | 10 studies | 25% ± 9% | |
microglial cell | 10 studies | 33% ± 8% | |
oligodendrocyte precursor cell | 10 studies | 36% ± 15% | |
adipocyte | 10 studies | 41% ± 15% | |
smooth muscle cell | 10 studies | 22% ± 6% | |
endothelial cell of artery | 9 studies | 23% ± 6% | |
glutamatergic neuron | 9 studies | 46% ± 27% | |
memory B cell | 9 studies | 29% ± 14% | |
endothelial cell of vascular tree | 9 studies | 27% ± 13% | |
GABAergic neuron | 8 studies | 44% ± 23% | |
T cell | 8 studies | 21% ± 3% | |
epithelial cell | 7 studies | 42% ± 20% | |
vein endothelial cell | 7 studies | 26% ± 16% | |
neuron | 6 studies | 35% ± 18% | |
interneuron | 6 studies | 41% ± 25% | |
conventional dendritic cell | 6 studies | 28% ± 9% | |
connective tissue cell | 6 studies | 23% ± 8% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 5 studies | 23% ± 7% | |
mucosal invariant T cell | 5 studies | 22% ± 4% | |
myofibroblast cell | 5 studies | 23% ± 9% | |
capillary endothelial cell | 5 studies | 24% ± 4% | |
CD8-positive, alpha-beta T cell | 5 studies | 27% ± 13% | |
basal cell | 5 studies | 34% ± 19% | |
endothelial cell of lymphatic vessel | 5 studies | 33% ± 6% | |
squamous epithelial cell | 4 studies | 41% ± 19% | |
classical monocyte | 4 studies | 30% ± 10% | |
innate lymphoid cell | 4 studies | 28% ± 17% | |
cardiac muscle cell | 4 studies | 19% ± 1% | |
lymphocyte | 4 studies | 28% ± 9% | |
mast cell | 4 studies | 34% ± 11% | |
T follicular helper cell | 4 studies | 26% ± 6% | |
brush cell | 4 studies | 49% ± 18% | |
secretory cell | 4 studies | 21% ± 4% | |
mononuclear phagocyte | 3 studies | 33% ± 9% | |
GABAergic interneuron | 3 studies | 26% ± 3% | |
granule cell | 3 studies | 23% ± 2% | |
retinal ganglion cell | 3 studies | 35% ± 5% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 16% ± 1% | |
mesothelial cell | 3 studies | 20% ± 5% | |
ciliated cell | 3 studies | 31% ± 18% | |
CD4-positive helper T cell | 3 studies | 38% ± 9% | |
hepatocyte | 3 studies | 42% ± 28% | |
muscle cell | 3 studies | 33% ± 16% | |
pancreatic ductal cell | 3 studies | 45% ± 19% | |
ependymal cell | 3 studies | 32% ± 13% | |
goblet cell | 3 studies | 39% ± 28% | |
leukocyte | 3 studies | 21% ± 6% | |
adventitial cell | 3 studies | 33% ± 4% | |
alveolar macrophage | 3 studies | 33% ± 8% | |
gamma-delta T cell | 3 studies | 19% ± 2% | |
abnormal cell | 3 studies | 29% ± 11% | |
luminal cell of prostate epithelium | 3 studies | 22% ± 5% | |
mucus secreting cell | 3 studies | 23% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 8376.53 | 459 / 459 | 100% | 73.29 | 1118 / 1118 |
stomach | 100% | 4839.40 | 359 / 359 | 100% | 63.55 | 286 / 286 |
intestine | 100% | 6304.94 | 966 / 966 | 100% | 66.22 | 526 / 527 |
prostate | 100% | 5096.01 | 244 / 245 | 100% | 67.33 | 502 / 502 |
kidney | 100% | 4187.08 | 89 / 89 | 100% | 52.45 | 897 / 901 |
esophagus | 100% | 6919.47 | 1445 / 1445 | 99% | 56.96 | 182 / 183 |
lung | 99% | 4285.77 | 575 / 578 | 100% | 47.91 | 1151 / 1155 |
adrenal gland | 100% | 4838.78 | 258 / 258 | 99% | 34.28 | 228 / 230 |
skin | 100% | 5556.33 | 1808 / 1809 | 99% | 67.20 | 468 / 472 |
ovary | 100% | 4782.30 | 180 / 180 | 99% | 34.52 | 426 / 430 |
bladder | 100% | 8123.67 | 21 / 21 | 99% | 47.86 | 499 / 504 |
thymus | 100% | 5378.38 | 652 / 653 | 99% | 59.05 | 598 / 605 |
pancreas | 98% | 2362.05 | 320 / 328 | 100% | 71.59 | 178 / 178 |
liver | 100% | 3350.99 | 225 / 226 | 98% | 33.97 | 397 / 406 |
uterus | 100% | 7897.71 | 170 / 170 | 97% | 43.62 | 443 / 459 |
brain | 95% | 2101.66 | 2516 / 2642 | 95% | 25.89 | 670 / 705 |
adipose | 100% | 10058.80 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 10422.82 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 3092.06 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 29.94 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 12.22 | 1 / 1 |
muscle | 99% | 2861.84 | 797 / 803 | 0% | 0 | 0 / 0 |
heart | 97% | 3372.16 | 837 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 26.87 | 28 / 29 |
eye | 0% | 0 | 0 / 0 | 88% | 30.25 | 70 / 80 |
peripheral blood | 29% | 805.54 | 273 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030838 | Biological process | positive regulation of actin filament polymerization |
GO_0006897 | Biological process | endocytosis |
GO_0051044 | Biological process | positive regulation of membrane protein ectodomain proteolysis |
GO_0043547 | Biological process | positive regulation of GTPase activity |
GO_0006898 | Biological process | receptor-mediated endocytosis |
GO_1900242 | Biological process | regulation of synaptic vesicle endocytosis |
GO_0006886 | Biological process | intracellular protein transport |
GO_0000281 | Biological process | mitotic cytokinesis |
GO_0097320 | Biological process | plasma membrane tubulation |
GO_0045860 | Biological process | positive regulation of protein kinase activity |
GO_0065003 | Biological process | protein-containing complex assembly |
GO_0016197 | Biological process | endosomal transport |
GO_0036089 | Biological process | cleavage furrow formation |
GO_0060988 | Biological process | lipid tube assembly |
GO_0001726 | Cellular component | ruffle |
GO_0098793 | Cellular component | presynapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0031410 | Cellular component | cytoplasmic vesicle |
GO_0070062 | Cellular component | extracellular exosome |
GO_0030136 | Cellular component | clathrin-coated vesicle |
GO_0005802 | Cellular component | trans-Golgi network |
GO_0032437 | Cellular component | cuticular plate |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005905 | Cellular component | clathrin-coated pit |
GO_0030659 | Cellular component | cytoplasmic vesicle membrane |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0045296 | Molecular function | cadherin binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
GO_0071933 | Molecular function | Arp2/3 complex binding |
GO_0035091 | Molecular function | phosphatidylinositol binding |
GO_0005545 | Molecular function | 1-phosphatidylinositol binding |
GO_0005515 | Molecular function | protein binding |
Gene name | SNX9 |
Protein name | Sorting nexin Sorting nexin 9 Sorting nexin-9 (SH3 and PX domain-containing protein 1) (Protein SDP1) (SH3 and PX domain-containing protein 3A) |
Synonyms | SH3PXD3A SH3PX1 |
Description | FUNCTION: Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate. . |
Accessions | ENST00000679814.1 A0A7P0T8L2 ENST00000681186.1 A0A087WZW2 ENST00000679790.1 A0A7P0T8C7 Q9Y5X1 ENST00000614800.4 A0A7P0Z4A5 A0A7P0T8M2 A0A7P0T8Z7 ENST00000680863.1 A0A7P0TBD0 A0A7P0T8S8 ENST00000680495.1 A0A7P0Z4A2 A0A7P0T8Z2 ENST00000680078.1 ENST00000679732.1 ENST00000679691.1 ENST00000392185.8 ENST00000681534.1 ENST00000681183.1 A0A087WVE4 ENST00000681651.1 A0A7P0TBI9 A0A7P0T8D4 ENST00000681138.1 ENST00000614703.4 |