Name | Number of supported studies | Average coverage | |
---|---|---|---|
T cell | 14 studies | 31% ± 13% | |
CD8-positive, alpha-beta T cell | 14 studies | 31% ± 12% | |
natural killer cell | 13 studies | 27% ± 13% | |
regulatory T cell | 11 studies | 25% ± 11% | |
CD4-positive, alpha-beta T cell | 10 studies | 38% ± 11% | |
endothelial cell | 9 studies | 24% ± 6% | |
epithelial cell | 9 studies | 34% ± 15% | |
type II pneumocyte | 8 studies | 23% ± 7% | |
plasmablast | 8 studies | 50% ± 21% | |
plasma cell | 7 studies | 28% ± 9% | |
fibroblast | 7 studies | 18% ± 2% | |
gamma-delta T cell | 7 studies | 34% ± 15% | |
endothelial cell of lymphatic vessel | 6 studies | 22% ± 4% | |
B cell | 6 studies | 37% ± 6% | |
transit amplifying cell | 6 studies | 33% ± 19% | |
conventional dendritic cell | 5 studies | 25% ± 8% | |
hematopoietic precursor cell | 5 studies | 35% ± 12% | |
abnormal cell | 5 studies | 23% ± 4% | |
pro-B cell | 5 studies | 45% ± 10% | |
type I pneumocyte | 5 studies | 24% ± 7% | |
erythrocyte | 5 studies | 36% ± 16% | |
effector CD8-positive, alpha-beta T cell | 5 studies | 33% ± 7% | |
deuterosomal cell | 4 studies | 33% ± 11% | |
progenitor cell | 4 studies | 22% ± 4% | |
connective tissue cell | 4 studies | 25% ± 4% | |
macrophage | 4 studies | 19% ± 5% | |
pericyte | 4 studies | 20% ± 6% | |
basal cell | 4 studies | 20% ± 4% | |
dendritic cell | 4 studies | 26% ± 10% | |
hematopoietic stem cell | 4 studies | 30% ± 11% | |
non-classical monocyte | 3 studies | 18% ± 3% | |
leukocyte | 3 studies | 31% ± 16% | |
neural crest cell | 3 studies | 45% ± 22% | |
vein endothelial cell | 3 studies | 20% ± 4% | |
lymphocyte | 3 studies | 33% ± 7% | |
squamous epithelial cell | 3 studies | 29% ± 9% | |
ciliated cell | 3 studies | 25% ± 7% | |
erythroblast | 3 studies | 60% ± 26% | |
oligodendrocyte | 3 studies | 18% ± 2% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 44% ± 13% | |
enteroendocrine cell | 3 studies | 18% ± 2% | |
goblet cell | 3 studies | 19% ± 5% | |
plasmacytoid dendritic cell | 3 studies | 21% ± 6% | |
precursor B cell | 3 studies | 60% ± 23% | |
CD8-positive, alpha-beta memory T cell | 3 studies | 20% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2280.20 | 1441 / 1445 | 100% | 54.94 | 183 / 183 |
lung | 100% | 1997.94 | 577 / 578 | 98% | 30.92 | 1137 / 1155 |
ovary | 100% | 939.43 | 180 / 180 | 98% | 25.08 | 420 / 430 |
stomach | 100% | 1199.53 | 359 / 359 | 97% | 27.27 | 277 / 286 |
intestine | 100% | 1532.76 | 965 / 966 | 95% | 22.15 | 501 / 527 |
breast | 100% | 964.46 | 459 / 459 | 95% | 29.00 | 1060 / 1118 |
uterus | 99% | 1047.62 | 169 / 170 | 93% | 41.17 | 425 / 459 |
bladder | 100% | 1082.14 | 21 / 21 | 90% | 21.53 | 456 / 504 |
skin | 100% | 3431.65 | 1804 / 1809 | 84% | 19.93 | 396 / 472 |
pancreas | 95% | 612.35 | 312 / 328 | 87% | 11.54 | 154 / 178 |
thymus | 100% | 1331.26 | 652 / 653 | 76% | 10.48 | 461 / 605 |
kidney | 97% | 634.94 | 86 / 89 | 62% | 6.88 | 563 / 901 |
adrenal gland | 100% | 1049.14 | 257 / 258 | 57% | 6.30 | 131 / 230 |
prostate | 98% | 760.44 | 241 / 245 | 44% | 3.99 | 219 / 502 |
liver | 88% | 614.80 | 199 / 226 | 47% | 6.37 | 192 / 406 |
spleen | 100% | 2076.59 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1592.10 | 1333 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 1013.44 | 1199 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 59.42 | 43 / 45 |
muscle | 94% | 566.82 | 758 / 803 | 0% | 0 | 0 / 0 |
heart | 91% | 750.12 | 787 / 861 | 0% | 0 | 0 / 0 |
brain | 34% | 143.71 | 891 / 2642 | 50% | 7.77 | 356 / 705 |
lymph node | 0% | 0 | 0 / 0 | 72% | 25.30 | 21 / 29 |
peripheral blood | 59% | 2765.41 | 544 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 15% | 1.01 | 12 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_1905821 | Biological process | positive regulation of chromosome condensation |
GO_0045132 | Biological process | meiotic chromosome segregation |
GO_0010032 | Biological process | meiotic chromosome condensation |
GO_0000070 | Biological process | mitotic sister chromatid segregation |
GO_0051301 | Biological process | cell division |
GO_0051984 | Biological process | positive regulation of chromosome segregation |
GO_1905820 | Biological process | positive regulation of chromosome separation |
GO_0007076 | Biological process | mitotic chromosome condensation |
GO_0051383 | Biological process | kinetochore organization |
GO_0000775 | Cellular component | chromosome, centromeric region |
GO_0016607 | Cellular component | nuclear speck |
GO_0005654 | Cellular component | nucleoplasm |
GO_0000796 | Cellular component | condensin complex |
GO_0005829 | Cellular component | cytosol |
GO_0000794 | Cellular component | condensed nuclear chromosome |
GO_0005634 | Cellular component | nucleus |
GO_0003682 | Molecular function | chromatin binding |
GO_0003697 | Molecular function | single-stranded DNA binding |
GO_0005524 | Molecular function | ATP binding |
GO_0005515 | Molecular function | protein binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
Gene name | SMC4 |
Protein name | Structural maintenance of chromosomes protein SMC4 protein Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4) (Chromosome-associated polypeptide C) (hCAP-C) (XCAP-C homolog) Structural maintenance of chromosomes 4 |
Synonyms | CAPC SMC4L1 |
Description | FUNCTION: Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. . |
Accessions | Q9NTJ3 C9JWF0 Q58F29 ENST00000465903.5 ENST00000490207.5 Q6P169 ENST00000485867.5 C9J9E4 C9JR83 ENST00000344722.5 [Q9NTJ3-1] F8WCB7 C9JVD8 ENST00000467468.5 ENST00000357388.8 [Q9NTJ3-1] ENST00000462787.5 [Q9NTJ3-2] ENST00000469762.5 ENST00000489573.5 C9J578 Q6NSG3 ENST00000469858.5 ENST00000472991.5 E9PD53 ENST00000485645.5 C9JJ64 C9IYK2 ENST00000497311.5 |