SIPA1L1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051056Biological processregulation of small GTPase mediated signal transduction
GO_0030036Biological processactin cytoskeleton organization
GO_0048167Biological processregulation of synaptic plasticity
GO_0048013Biological processephrin receptor signaling pathway
GO_0061001Biological processregulation of dendritic spine morphogenesis
GO_0043087Biological processregulation of GTPase activity
GO_0090630Biological processactivation of GTPase activity
GO_0008150Biological processbiological_process
GO_0050770Biological processregulation of axonogenesis
GO_0014069Cellular componentpostsynaptic density
GO_0015629Cellular componentactin cytoskeleton
GO_0043197Cellular componentdendritic spine
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0046875Molecular functionephrin receptor binding
GO_0005515Molecular functionprotein binding
GO_0003674Molecular functionmolecular_function
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameSIPA1L1
Protein nameSIPA1L1 protein
Signal-induced proliferation-associated 1-like protein 1 (SIPA1-like protein 1) (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6-targeted protein 1)
Signal induced proliferation associated 1 like 1
SynonymsE6TP1
KIAA0440
DescriptionFUNCTION: Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F-actin. Contributes to the regulation of dendritic spine morphogenesis (By similarity). .

AccessionsENST00000537413.5
ENST00000555818.5 [O43166-1]
ENST00000555066.1
H0YJY2
ENST00000381232.8 [O43166-2]
A6H8W6
ENST00000358550.6 [O43166-3]
G3V4Z3
F5GYF8
ENST00000557151.5
O43166