I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 10 studies | 31% ± 12% | |
| vein endothelial cell | 9 studies | 35% ± 18% | |
| endothelial cell of vascular tree | 7 studies | 52% ± 14% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 10 studies | 31% ± 12% | |
| vein endothelial cell | 9 studies | 35% ± 18% | |
| endothelial cell of vascular tree | 7 studies | 52% ± 14% |
Insufficient scRNA-seq data for expression of SELE at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 87% | 1563.88 | 212 / 245 | 76% | 16.71 | 383 / 502 |
| thymus | 92% | 2817.36 | 603 / 653 | 59% | 7.14 | 358 / 605 |
| breast | 73% | 2287.52 | 333 / 459 | 69% | 7.78 | 768 / 1118 |
| esophagus | 50% | 497.43 | 722 / 1445 | 63% | 7.79 | 116 / 183 |
| lung | 69% | 1773.37 | 401 / 578 | 38% | 3.38 | 436 / 1155 |
| ureter | 0% | 0 | 0 / 0 | 100% | 6.22 | 1 / 1 |
| stomach | 42% | 782.12 | 152 / 359 | 57% | 4.60 | 162 / 286 |
| kidney | 62% | 752.94 | 55 / 89 | 36% | 2.32 | 323 / 901 |
| liver | 73% | 487.62 | 165 / 226 | 22% | 1.19 | 88 / 406 |
| uterus | 56% | 916.59 | 96 / 170 | 27% | 2.64 | 124 / 459 |
| bladder | 33% | 303.10 | 7 / 21 | 48% | 6.09 | 241 / 504 |
| intestine | 38% | 507.70 | 363 / 966 | 42% | 3.60 | 223 / 527 |
| skin | 40% | 382.41 | 730 / 1809 | 30% | 2.03 | 140 / 472 |
| adipose | 70% | 2943.87 | 838 / 1204 | 0% | 0 | 0 / 0 |
| pancreas | 14% | 70.12 | 46 / 328 | 49% | 4.40 | 87 / 178 |
| adrenal gland | 37% | 790.05 | 95 / 258 | 20% | 2.30 | 46 / 230 |
| tonsil | 0% | 0 | 0 / 0 | 56% | 12.40 | 25 / 45 |
| blood vessel | 51% | 829.12 | 680 / 1335 | 0% | 0 | 0 / 0 |
| heart | 50% | 790.13 | 432 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 45% | 3.46 | 13 / 29 |
| ovary | 38% | 545.61 | 68 / 180 | 4% | 0.12 | 16 / 430 |
| brain | 15% | 235.05 | 407 / 2642 | 5% | 0.52 | 37 / 705 |
| muscle | 6% | 60.64 | 52 / 803 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0.76 | 1 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 2.38 | 2 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006954 | Biological process | inflammatory response |
| GO_0019722 | Biological process | calcium-mediated signaling |
| GO_0034097 | Biological process | response to cytokine |
| GO_0002523 | Biological process | leukocyte migration involved in inflammatory response |
| GO_0030029 | Biological process | actin filament-based process |
| GO_0070555 | Biological process | response to interleukin-1 |
| GO_0050727 | Biological process | regulation of inflammatory response |
| GO_0034612 | Biological process | response to tumor necrosis factor |
| GO_0002092 | Biological process | positive regulation of receptor internalization |
| GO_1903238 | Biological process | positive regulation of leukocyte tethering or rolling |
| GO_0050901 | Biological process | leukocyte tethering or rolling |
| GO_0002687 | Biological process | positive regulation of leukocyte migration |
| GO_0007157 | Biological process | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules |
| GO_0032496 | Biological process | response to lipopolysaccharide |
| GO_0007159 | Biological process | leukocyte cell-cell adhesion |
| GO_0005615 | Cellular component | extracellular space |
| GO_0009897 | Cellular component | external side of plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0045121 | Cellular component | membrane raft |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0030863 | Cellular component | cortical cytoskeleton |
| GO_0005905 | Cellular component | clathrin-coated pit |
| GO_0005901 | Cellular component | caveola |
| GO_0033691 | Molecular function | sialic acid binding |
| GO_0004888 | Molecular function | transmembrane signaling receptor activity |
| GO_0070492 | Molecular function | oligosaccharide binding |
| GO_0043274 | Molecular function | phospholipase binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SELE |
| Protein name | E-selectin (CD62 antigen-like family member E) (Endothelial leukocyte adhesion molecule 1) (Leukocyte-endothelial cell adhesion molecule 2) E-selectin (CD62 antigen-like family member E) (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD antigen CD62E) Selectin E |
| Synonyms | ELAM1 |
| Description | FUNCTION: Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis. . |
| Accessions | ENST00000367776.5 ENST00000367775.5 V9GYI4 ENST00000367777.5 Q5TI74 ENST00000333360.12 P16581 Q5TI75 Q5TI73 Q5TI72 ENST00000609271.1 ENST00000367774.1 |
