RREB1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006366Biological processtranscription by RNA polymerase II
GO_2000394Biological processpositive regulation of lamellipodium morphogenesis
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_1903691Biological processpositive regulation of wound healing, spreading of epidermal cells
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0090336Biological processpositive regulation of brown fat cell differentiation
GO_0006355Biological processregulation of DNA-templated transcription
GO_0033601Biological processpositive regulation of mammary gland epithelial cell proliferation
GO_1900026Biological processpositive regulation of substrate adhesion-dependent cell spreading
GO_0010634Biological processpositive regulation of epithelial cell migration
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0016607Cellular componentnuclear speck
GO_0070062Cellular componentextracellular exosome
GO_0001650Cellular componentfibrillar center
GO_0016604Cellular componentnuclear body
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameRREB1
Protein nameRas-responsive element-binding protein 1 (RREB-1) (Finger protein in nuclear bodies) (Raf-responsive zinc finger protein LZ321) (Zinc finger motif enhancer-binding protein 1) (Zep-1)
Ras responsive element binding protein 1
SynonymsFINB
DescriptionFUNCTION: Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters . Represses the angiotensinogen gene . Negatively regulates the transcriptional activity of AR . Potentiates the transcriptional activity of NEUROD1 . Promotes brown adipocyte differentiation (By similarity). May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression . .

AccessionsENST00000334984.10 [Q92766-3]
ENST00000379938.7 [Q92766-2]
C9JE09
ENST00000491191.5
Q92766
C9JU34
C9JPJ6
ENST00000471433.5
ENST00000483150.1
ENST00000379933.7 [Q92766-1]
ENST00000349384.10 [Q92766-1]