Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 20 studies | 29% ± 11% | |
| macrophage | 16 studies | 38% ± 20% | |
| astrocyte | 11 studies | 28% ± 14% | |
| microglial cell | 11 studies | 42% ± 15% | |
| myeloid cell | 10 studies | 36% ± 17% | |
| adipocyte | 9 studies | 47% ± 9% | |
| fibroblast | 9 studies | 24% ± 8% | |
| epithelial cell | 8 studies | 40% ± 21% | |
| basal cell | 8 studies | 33% ± 20% | |
| dendritic cell | 8 studies | 35% ± 14% | |
| mast cell | 7 studies | 25% ± 6% | |
| ciliated cell | 7 studies | 27% ± 8% | |
| club cell | 6 studies | 26% ± 8% | |
| endothelial cell of lymphatic vessel | 6 studies | 38% ± 11% | |
| type II pneumocyte | 6 studies | 26% ± 9% | |
| B cell | 5 studies | 22% ± 4% | |
| monocyte | 5 studies | 43% ± 8% | |
| goblet cell | 5 studies | 33% ± 29% | |
| pericyte | 5 studies | 25% ± 7% | |
| type I pneumocyte | 5 studies | 25% ± 9% | |
| classical monocyte | 4 studies | 25% ± 7% | |
| cardiac muscle cell | 4 studies | 29% ± 2% | |
| hepatocyte | 4 studies | 65% ± 23% | |
| respiratory goblet cell | 4 studies | 38% ± 7% | |
| smooth muscle cell | 4 studies | 21% ± 1% | |
| hematopoietic precursor cell | 3 studies | 35% ± 17% | |
| non-classical monocyte | 3 studies | 27% ± 7% | |
| plasma cell | 3 studies | 30% ± 4% | |
| mononuclear phagocyte | 3 studies | 33% ± 8% | |
| vein endothelial cell | 3 studies | 34% ± 21% | |
| lymphocyte | 3 studies | 27% ± 12% | |
| retinal cone cell | 3 studies | 29% ± 9% | |
| retinal rod cell | 3 studies | 26% ± 6% | |
| ependymal cell | 3 studies | 30% ± 8% | |
| megakaryocyte-erythroid progenitor cell | 3 studies | 26% ± 5% | |
| T cell | 3 studies | 21% ± 3% | |
| alveolar macrophage | 3 studies | 57% ± 15% | |
| capillary endothelial cell | 3 studies | 20% ± 5% | |
| plasmacytoid dendritic cell | 3 studies | 27% ± 7% | |
| mucus secreting cell | 3 studies | 39% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 5276.51 | 1445 / 1445 | 100% | 29.37 | 183 / 183 |
| prostate | 100% | 3543.27 | 245 / 245 | 100% | 13.95 | 502 / 502 |
| intestine | 100% | 3976.12 | 966 / 966 | 100% | 15.42 | 526 / 527 |
| breast | 100% | 4796.86 | 459 / 459 | 100% | 16.08 | 1115 / 1118 |
| skin | 100% | 5259.60 | 1809 / 1809 | 100% | 11.11 | 470 / 472 |
| pancreas | 100% | 2977.92 | 328 / 328 | 99% | 10.91 | 177 / 178 |
| lung | 100% | 3988.45 | 578 / 578 | 99% | 15.53 | 1148 / 1155 |
| thymus | 100% | 5428.83 | 653 / 653 | 99% | 13.97 | 600 / 605 |
| stomach | 100% | 2935.07 | 359 / 359 | 99% | 18.10 | 283 / 286 |
| bladder | 100% | 3267.57 | 21 / 21 | 99% | 11.71 | 498 / 504 |
| uterus | 100% | 3350.03 | 170 / 170 | 98% | 13.11 | 452 / 459 |
| ovary | 100% | 3560.29 | 180 / 180 | 98% | 12.57 | 423 / 430 |
| kidney | 100% | 2713.96 | 89 / 89 | 98% | 11.00 | 886 / 901 |
| liver | 100% | 4005.12 | 226 / 226 | 98% | 10.83 | 397 / 406 |
| adrenal gland | 100% | 4797.59 | 258 / 258 | 77% | 4.88 | 178 / 230 |
| adipose | 100% | 4438.16 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 13.22 | 80 / 80 |
| muscle | 100% | 3879.66 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4549.95 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.72 | 1 / 1 |
| blood vessel | 100% | 2287.91 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 16.10 | 44 / 45 |
| heart | 97% | 2136.53 | 833 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 5.46 | 24 / 29 |
| peripheral blood | 79% | 1612.92 | 731 / 929 | 0% | 0 | 0 / 0 |
| brain | 12% | 111.23 | 325 / 2642 | 49% | 2.40 | 344 / 705 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006366 | Biological process | transcription by RNA polymerase II |
| GO_2000394 | Biological process | positive regulation of lamellipodium morphogenesis |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_1903691 | Biological process | positive regulation of wound healing, spreading of epidermal cells |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0090336 | Biological process | positive regulation of brown fat cell differentiation |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0033601 | Biological process | positive regulation of mammary gland epithelial cell proliferation |
| GO_1900026 | Biological process | positive regulation of substrate adhesion-dependent cell spreading |
| GO_0010634 | Biological process | positive regulation of epithelial cell migration |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0016607 | Cellular component | nuclear speck |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0001650 | Cellular component | fibrillar center |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | RREB1 |
| Protein name | Ras-responsive element-binding protein 1 (RREB-1) (Finger protein in nuclear bodies) (Raf-responsive zinc finger protein LZ321) (Zinc finger motif enhancer-binding protein 1) (Zep-1) Ras responsive element binding protein 1 |
| Synonyms | FINB |
| Description | FUNCTION: Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters . Represses the angiotensinogen gene . Negatively regulates the transcriptional activity of AR . Potentiates the transcriptional activity of NEUROD1 . Promotes brown adipocyte differentiation (By similarity). May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression . . |
| Accessions | ENST00000334984.10 [Q92766-3] ENST00000379938.7 [Q92766-2] C9JE09 ENST00000491191.5 Q92766 C9JU34 C9JPJ6 ENST00000471433.5 ENST00000483150.1 ENST00000379933.7 [Q92766-1] ENST00000349384.10 [Q92766-1] |