Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 18 studies | 48% ± 21% | |
astrocyte | 14 studies | 40% ± 20% | |
type I pneumocyte | 6 studies | 31% ± 12% | |
fibroblast | 5 studies | 26% ± 7% | |
endothelial cell | 4 studies | 36% ± 12% | |
myeloid cell | 4 studies | 22% ± 5% | |
endothelial cell of lymphatic vessel | 4 studies | 30% ± 10% | |
glutamatergic neuron | 4 studies | 24% ± 3% | |
smooth muscle cell | 4 studies | 22% ± 3% | |
deuterosomal cell | 3 studies | 18% ± 4% | |
epithelial cell | 3 studies | 35% ± 19% | |
mesothelial cell | 3 studies | 33% ± 8% | |
ependymal cell | 3 studies | 72% ± 8% | |
monocyte | 3 studies | 27% ± 12% | |
alveolar macrophage | 3 studies | 28% ± 10% | |
macrophage | 3 studies | 16% ± 1% | |
type II pneumocyte | 3 studies | 26% ± 8% | |
interneuron | 3 studies | 21% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 99% | 2863.57 | 1435 / 1445 | 99% | 7.14 | 182 / 183 |
lung | 99% | 2030.53 | 575 / 578 | 98% | 5.21 | 1130 / 1155 |
uterus | 100% | 3351.41 | 170 / 170 | 97% | 6.08 | 445 / 459 |
bladder | 100% | 1936.00 | 21 / 21 | 97% | 4.25 | 488 / 504 |
ovary | 100% | 1263.54 | 180 / 180 | 96% | 4.61 | 411 / 430 |
prostate | 99% | 1313.74 | 243 / 245 | 96% | 2.92 | 482 / 502 |
breast | 97% | 1422.92 | 447 / 459 | 95% | 3.62 | 1066 / 1118 |
intestine | 96% | 2557.47 | 930 / 966 | 94% | 3.39 | 493 / 527 |
brain | 89% | 822.68 | 2354 / 2642 | 100% | 11.99 | 705 / 705 |
thymus | 91% | 777.24 | 593 / 653 | 98% | 4.26 | 591 / 605 |
skin | 99% | 1424.04 | 1796 / 1809 | 83% | 2.49 | 392 / 472 |
stomach | 68% | 1108.60 | 244 / 359 | 97% | 3.90 | 276 / 286 |
adrenal gland | 58% | 285.80 | 149 / 258 | 88% | 3.07 | 202 / 230 |
kidney | 54% | 338.87 | 48 / 89 | 89% | 4.68 | 798 / 901 |
pancreas | 8% | 42.61 | 26 / 328 | 99% | 5.82 | 176 / 178 |
tonsil | 0% | 0 | 0 / 0 | 100% | 4.99 | 45 / 45 |
blood vessel | 99% | 1476.09 | 1321 / 1335 | 0% | 0 | 0 / 0 |
adipose | 98% | 1472.88 | 1175 / 1204 | 0% | 0 | 0 / 0 |
spleen | 91% | 624.25 | 220 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 90% | 2134.57 | 837 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 83% | 3.66 | 24 / 29 |
eye | 0% | 0 | 0 / 0 | 83% | 1.81 | 66 / 80 |
heart | 77% | 800.63 | 660 / 861 | 0% | 0 | 0 / 0 |
liver | 5% | 27.32 | 12 / 226 | 42% | 1.06 | 171 / 406 |
muscle | 8% | 43.78 | 66 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0060271 | Biological process | cilium assembly |
GO_1990830 | Biological process | cellular response to leukemia inhibitory factor |
GO_0001675 | Biological process | acrosome assembly |
GO_0007286 | Biological process | spermatid development |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0000785 | Cellular component | chromatin |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0005515 | Molecular function | protein binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
Gene name | RFX2 |
Protein name | DNA-binding protein RFX2 (Regulatory factor X 2) Regulatory factor X2 RFX2_HUMAN, [AA 620-723] |
Synonyms | |
Description | FUNCTION: Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function (By similarity). Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters . Probably activates transcription of the testis-specific histone gene H1-6 (By similarity). . |
Accessions | ENST00000592281.5 ENST00000359161.7 [P48378-1] K7EJE4 ENST00000592883.5 K7EQA0 ENST00000592473.5 ENST00000589742.5 ENST00000593241.5 ENST00000592546.5 [P48378-2] ENST00000303657.10 [P48378-1] K7EJD4 ENST00000587321.1 K7ELQ7 K7ENC9 K7EQU2 K7ES56 P48378 Q75MR3 ENST00000586806.1 K7ELD5 ENST00000589340.1 K7EIN5 ENST00000587181.1 ENST00000586302.5 K7EQY9 |