RBM47 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0002244Biological processhematopoietic progenitor cell differentiation
GO_0016554Biological processcytidine to uridine editing
GO_0008380Biological processRNA splicing
GO_0006397Biological processmRNA processing
GO_0032733Biological processpositive regulation of interleukin-10 production
GO_0060340Biological processpositive regulation of type I interferon-mediated signaling pathway
GO_0000381Biological processregulation of alternative mRNA splicing, via spliceosome
GO_0070935Biological process3'-UTR-mediated mRNA stabilization
GO_0030895Cellular componentapolipoprotein B mRNA editing enzyme complex
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0140767Molecular functionenzyme-substrate adaptor activity
GO_0019899Molecular functionenzyme binding
GO_0003730Molecular functionmRNA 3'-UTR binding
GO_0005515Molecular functionprotein binding
GO_0003729Molecular functionmRNA binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameRBM47
Protein nameRNA-binding protein 47 (RNA-binding motif protein 47)
RNA binding motif protein 47
Synonyms
DescriptionFUNCTION: Single-stranded RNA-binding protein that functions in a variety of RNA processes, including alternative splicing, RNA stabilization, and RNA editing . Functions as an enzyme-substrate adapter for the cytidine deaminase APOBEC1. With APOBEC1 forms an mRNA editing complex involved into cytidine to uridine editing of a variety of mRNA molecules . Through the binding of their 3'UTR, also stabilizes a variety of mRNAs and regulates the expression of genes such as the interferon alpha/beta receptor and interleukin-10 . Also involved in the alternative splicing of several genes including TJP1. Binds the pre-mRNA (U)GCAUG consensus sequences in downstream intronic regions of alternative exons, regulating their exclusion and inclusion into mRNAs . Independently of its RNA-binding activity, could negatively regulate MAVS by promoting its lysosomal degradation (By similarity). .

AccessionsD6RBS9
B7Z8Z7
B7ZLP7
ENST00000507180.5
ENST00000510871.5
D6RBP6
ENST00000295971.12 [A0AV96-1]
ENST00000514014.1
ENST00000514782.5
ENST00000381793.6 [A0AV96-1]
D6R9D6
ENST00000381795.10 [A0AV96-2]
A0AV96
ENST00000505414.5
ENST00000511598.5
D6R9M7
D6RCT1
ENST00000513473.5
D6RA49
ENST00000515053.5
ENST00000511902.5
ENST00000505220.1
D6REZ6
D6RFL5