RABGGTB | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	13 studies	21% ± 5%	Explore
memory B cell	10 studies	19% ± 3%	Explore
epithelial cell	8 studies	32% ± 17%	Explore
natural killer cell	7 studies	22% ± 3%	Explore
macrophage	7 studies	19% ± 5%	Explore
naive B cell	7 studies	22% ± 6%	Explore
CD4-positive, alpha-beta T cell	6 studies	23% ± 5%	Explore
conventional dendritic cell	6 studies	27% ± 13%	Explore
endothelial cell	6 studies	24% ± 7%	Explore
fibroblast	6 studies	21% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	19% ± 2%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	18% ± 2%	Explore
epithelial cell of proximal tubule	5 studies	23% ± 8%	Explore
CD8-positive, alpha-beta T cell	5 studies	22% ± 5%	Explore
T cell	4 studies	17% ± 2%	Explore
pancreatic A cell	4 studies	30% ± 12%	Explore
type B pancreatic cell	4 studies	38% ± 15%	Explore
non-classical monocyte	4 studies	28% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	17% ± 1%	Explore
immature B cell	4 studies	26% ± 11%	Explore
alveolar macrophage	4 studies	21% ± 3%	Explore
pericyte	4 studies	19% ± 3%	Explore
T follicular helper cell	4 studies	18% ± 1%	Explore
gamma-delta T cell	4 studies	29% ± 12%	Explore
plasmacytoid dendritic cell	4 studies	27% ± 9%	Explore
regulatory T cell	4 studies	21% ± 4%	Explore
basal cell	4 studies	27% ± 9%	Explore
classical monocyte	3 studies	22% ± 5%	Explore
retinal ganglion cell	3 studies	56% ± 25%	Explore
abnormal cell	3 studies	17% ± 2%	Explore
smooth muscle cell	3 studies	19% ± 2%	Explore
mucosal invariant T cell	3 studies	20% ± 2%	Explore
myeloid cell	3 studies	24% ± 8%	Explore
plasma cell	3 studies	28% ± 8%	Explore
precursor B cell	3 studies	27% ± 1%	Explore
ciliated cell	3 studies	26% ± 7%	Explore
GABAergic neuron	3 studies	22% ± 3%	Explore
glutamatergic neuron	3 studies	29% ± 6%	Explore
dendritic cell	3 studies	42% ± 13%	Explore
pancreatic ductal cell	3 studies	32% ± 11%	Explore
goblet cell	3 studies	22% ± 6%	Explore
intestinal crypt stem cell	3 studies	18% ± 1%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	20% ± 4%	Explore
endothelial cell of vascular tree	3 studies	19% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	6 studies	20% ± 5%	Explore
lung	4 studies	22% ± 2%	Explore
brain	4 studies	21% ± 6%	Explore
pancreas	3 studies	37% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	3603.05	21 / 21	100%	27.12	504 / 504
esophagus	100%	3389.00	1445 / 1445	100%	24.46	183 / 183
liver	100%	3075.02	226 / 226	100%	25.69	406 / 406
lung	100%	5206.67	578 / 578	100%	25.01	1155 / 1155
ovary	100%	4139.44	180 / 180	100%	20.43	430 / 430
pancreas	100%	3706.92	328 / 328	100%	24.79	178 / 178
prostate	100%	3312.18	245 / 245	100%	27.58	502 / 502
uterus	100%	3397.98	170 / 170	100%	28.66	459 / 459
breast	100%	4494.53	459 / 459	100%	31.64	1117 / 1118
kidney	100%	3734.79	89 / 89	100%	25.49	899 / 901
thymus	100%	3610.21	653 / 653	100%	27.24	603 / 605
brain	100%	2459.67	2633 / 2642	100%	25.71	705 / 705
intestine	100%	3826.66	966 / 966	100%	28.73	525 / 527
stomach	100%	3048.50	359 / 359	99%	24.62	284 / 286
adrenal gland	100%	5050.35	258 / 258	99%	25.07	228 / 230
skin	100%	4136.28	1809 / 1809	99%	29.58	465 / 472
adipose	100%	4239.56	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	25.44	80 / 80
lymph node	0%	0	0 / 0	100%	29.23	29 / 29
muscle	100%	4352.04	803 / 803	0%	0	0 / 0
spleen	100%	4800.93	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	20.65	45 / 45
ureter	0%	0	0 / 0	100%	15.29	1 / 1
blood vessel	100%	3214.55	1334 / 1335	0%	0	0 / 0
heart	97%	2930.18	833 / 861	0%	0	0 / 0
peripheral blood	50%	2162.37	462 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007601	Biological process	visual perception
GO_0018344	Biological process	protein geranylgeranylation
GO_0036211	Biological process	protein modification process
GO_0005968	Cellular component	Rab-protein geranylgeranyltransferase complex
GO_0005829	Cellular component	cytosol
GO_0005886	Cellular component	plasma membrane
GO_0005515	Molecular function	protein binding
GO_0008270	Molecular function	zinc ion binding
GO_0031267	Molecular function	small GTPase binding
GO_0004663	Molecular function	Rab geranylgeranyltransferase activity

IV. Literature review

[source]

Gene name	RABGGTB
Protein name	Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta) Rab geranylgeranyltransferase subunit beta
Synonyms	GGTB hCG_22856
Description	FUNCTION: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A. . FUNCTION: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX. .
Accessions	ENST00000319942.8 ENST00000370826.3 Q6IB63 P53611 Q5T4U8

RABGGTB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review