Name | Number of supported studies | Average coverage | |
---|---|---|---|
smooth muscle cell | 33 studies | 44% ± 16% | |
pericyte | 30 studies | 31% ± 13% | |
fibroblast | 18 studies | 36% ± 15% | |
astrocyte | 16 studies | 42% ± 18% | |
oligodendrocyte | 15 studies | 58% ± 15% | |
endothelial cell | 14 studies | 38% ± 14% | |
glutamatergic neuron | 12 studies | 52% ± 26% | |
microglial cell | 12 studies | 30% ± 13% | |
GABAergic neuron | 11 studies | 47% ± 25% | |
myofibroblast cell | 10 studies | 35% ± 17% | |
oligodendrocyte precursor cell | 10 studies | 35% ± 9% | |
adipocyte | 9 studies | 66% ± 13% | |
epithelial cell | 7 studies | 30% ± 15% | |
macrophage | 7 studies | 29% ± 12% | |
neuron | 6 studies | 44% ± 18% | |
interneuron | 6 studies | 57% ± 24% | |
cardiac muscle cell | 6 studies | 84% ± 10% | |
ciliated cell | 6 studies | 34% ± 16% | |
basal cell | 6 studies | 26% ± 13% | |
ionocyte | 5 studies | 52% ± 16% | |
mesothelial cell | 5 studies | 33% ± 14% | |
connective tissue cell | 5 studies | 21% ± 4% | |
type I pneumocyte | 5 studies | 32% ± 8% | |
type II pneumocyte | 5 studies | 32% ± 7% | |
granule cell | 4 studies | 46% ± 15% | |
retinal ganglion cell | 4 studies | 26% ± 14% | |
retinal pigment epithelial cell | 4 studies | 37% ± 15% | |
amacrine cell | 4 studies | 24% ± 12% | |
retina horizontal cell | 4 studies | 24% ± 11% | |
muscle cell | 4 studies | 57% ± 26% | |
club cell | 4 studies | 32% ± 8% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 50% ± 9% | |
GABAergic interneuron | 3 studies | 47% ± 3% | |
Purkinje cell | 3 studies | 58% ± 28% | |
glial cell | 3 studies | 33% ± 10% | |
plasma cell | 3 studies | 24% ± 6% | |
GABAergic amacrine cell | 3 studies | 27% ± 10% | |
glycinergic amacrine cell | 3 studies | 22% ± 2% | |
retinal cone cell | 3 studies | 26% ± 9% | |
rod bipolar cell | 3 studies | 35% ± 16% | |
mast cell | 3 studies | 30% ± 13% | |
endothelial cell of lymphatic vessel | 3 studies | 24% ± 3% | |
endothelial cell of vascular tree | 3 studies | 26% ± 13% | |
hepatocyte | 3 studies | 49% ± 14% | |
ependymal cell | 3 studies | 76% ± 12% | |
adventitial cell | 3 studies | 24% ± 5% | |
T cell | 3 studies | 22% ± 3% | |
alveolar macrophage | 3 studies | 23% ± 7% | |
monocyte | 3 studies | 25% ± 1% | |
respiratory goblet cell | 3 studies | 31% ± 11% | |
goblet cell | 3 studies | 29% ± 13% | |
renal alpha-intercalated cell | 3 studies | 42% ± 18% | |
mucus secreting cell | 3 studies | 31% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 95% | 28625.64 | 233 / 245 | 100% | 37.53 | 502 / 502 |
bladder | 100% | 45436.43 | 21 / 21 | 76% | 8.96 | 382 / 504 |
uterus | 98% | 55239.71 | 167 / 170 | 74% | 28.16 | 338 / 459 |
esophagus | 78% | 44689.93 | 1129 / 1445 | 93% | 17.88 | 171 / 183 |
intestine | 84% | 55984.63 | 815 / 966 | 87% | 10.06 | 459 / 527 |
breast | 74% | 9485.33 | 341 / 459 | 92% | 8.74 | 1031 / 1118 |
lung | 71% | 9774.71 | 408 / 578 | 85% | 14.44 | 984 / 1155 |
stomach | 54% | 20584.28 | 195 / 359 | 91% | 22.70 | 259 / 286 |
ovary | 89% | 13794.66 | 160 / 180 | 47% | 2.90 | 204 / 430 |
brain | 28% | 2536.31 | 730 / 2642 | 96% | 11.60 | 675 / 705 |
thymus | 32% | 3400.16 | 206 / 653 | 77% | 4.71 | 464 / 605 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.17 | 1 / 1 |
blood vessel | 100% | 71535.50 | 1333 / 1335 | 0% | 0 | 0 / 0 |
muscle | 98% | 19489.63 | 788 / 803 | 0% | 0 | 0 / 0 |
heart | 93% | 46765.65 | 802 / 861 | 0% | 0 | 0 / 0 |
skin | 21% | 2178.92 | 377 / 1809 | 72% | 8.61 | 341 / 472 |
kidney | 15% | 1385.75 | 13 / 89 | 78% | 9.51 | 703 / 901 |
pancreas | 0% | 31.78 | 1 / 328 | 92% | 12.43 | 164 / 178 |
adipose | 71% | 10655.21 | 857 / 1204 | 0% | 0 | 0 / 0 |
spleen | 67% | 6461.65 | 161 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 67% | 5.94 | 30 / 45 |
adrenal gland | 1% | 130.85 | 3 / 258 | 65% | 5.76 | 150 / 230 |
lymph node | 0% | 0 | 0 / 0 | 55% | 2.95 | 16 / 29 |
liver | 0% | 30.47 | 1 / 226 | 37% | 2.35 | 149 / 406 |
eye | 0% | 0 | 0 / 0 | 35% | 1.97 | 28 / 80 |
peripheral blood | 2% | 193.35 | 21 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007165 | Biological process | signal transduction |
GO_0006937 | Biological process | regulation of muscle contraction |
GO_0001725 | Cellular component | stress fiber |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0030018 | Cellular component | Z disc |
GO_0031672 | Cellular component | A band |
GO_0005737 | Cellular component | cytoplasm |
GO_0008047 | Molecular function | enzyme activator activity |
GO_0004857 | Molecular function | enzyme inhibitor activity |
GO_0019901 | Molecular function | protein kinase binding |
GO_0005515 | Molecular function | protein binding |
GO_0019208 | Molecular function | phosphatase regulator activity |
Gene name | PPP1R12B |
Protein name | Protein phosphatase 1 regulatory subunit 12B Protein phosphatase 1 regulatory subunit Protein phosphatase 1 regulatory subunit 12B isoform 2 Protein phosphatase 1 regulatory subunit 12B (Smooth muscle type of myosin light chain phosphatase small subunit) Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2) Protein phosphatase 1 regulatory subunit 12B isoform 1 PPP1R12B protein (Protein phosphatase 1 regulatory subunit 12B) |
Synonyms | MYPT2 sm-M20 hCG_2027314 |
Description | FUNCTION: Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus. . |
Accessions | ENST00000466968.1 ENST00000634903.1 A0A0S2Z473 ENST00000480184.5 [O60237-5] A0A994J7P4 ENST00000466273.6 ENST00000491336.5 [O60237-4] ENST00000608999.6 [O60237-1] H7C4R6 E1CKY7 A0A0S2Z4Q8 Q6GQY8 ENST00000434615.2 ENST00000391959.5 [O60237-6] A0A0U1RQI8 ENST00000704899.1 O60237 ENST00000356764.6 [O60237-2] ENST00000290419.9 [O60237-3] A0A0U1RQP2 ENST00000476364.5 |