PPP1R12B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0006937Biological processregulation of muscle contraction
GO_0001725Cellular componentstress fiber
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0030018Cellular componentZ disc
GO_0031672Cellular componentA band
GO_0005737Cellular componentcytoplasm
GO_0008047Molecular functionenzyme activator activity
GO_0004857Molecular functionenzyme inhibitor activity
GO_0019901Molecular functionprotein kinase binding
GO_0005515Molecular functionprotein binding
GO_0019208Molecular functionphosphatase regulator activity

IV. Literature review

[source]
Gene namePPP1R12B
Protein nameProtein phosphatase 1 regulatory subunit 12B
Protein phosphatase 1 regulatory subunit
Protein phosphatase 1 regulatory subunit 12B isoform 2
Protein phosphatase 1 regulatory subunit 12B (Smooth muscle type of myosin light chain phosphatase small subunit)
Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2)
Protein phosphatase 1 regulatory subunit 12B isoform 1
PPP1R12B protein (Protein phosphatase 1 regulatory subunit 12B)
SynonymsMYPT2
sm-M20
hCG_2027314
DescriptionFUNCTION: Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus. .

AccessionsENST00000466968.1
ENST00000634903.1
A0A0S2Z473
ENST00000480184.5 [O60237-5]
A0A994J7P4
ENST00000466273.6
ENST00000491336.5 [O60237-4]
ENST00000608999.6 [O60237-1]
H7C4R6
E1CKY7
A0A0S2Z4Q8
Q6GQY8
ENST00000434615.2
ENST00000391959.5 [O60237-6]
A0A0U1RQI8
ENST00000704899.1
O60237
ENST00000356764.6 [O60237-2]
ENST00000290419.9 [O60237-3]
A0A0U1RQP2
ENST00000476364.5