Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| macrophage | 8 studies | 24% ± 7% | |
| basal cell | 8 studies | 34% ± 10% | |
| fibroblast | 8 studies | 20% ± 4% | |
| epithelial cell | 6 studies | 38% ± 16% | |
| secretory cell | 5 studies | 38% ± 16% | |
| kidney loop of Henle epithelial cell | 4 studies | 27% ± 7% | |
| myeloid cell | 4 studies | 30% ± 5% | |
| dendritic cell | 3 studies | 18% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| prostate | 3 studies | 34% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 99% | 1973.04 | 574 / 578 | 91% | 171.46 | 1049 / 1155 |
| breast | 96% | 1629.92 | 439 / 459 | 89% | 88.50 | 996 / 1118 |
| esophagus | 94% | 1052.27 | 1354 / 1445 | 87% | 127.26 | 159 / 183 |
| intestine | 90% | 1030.30 | 865 / 966 | 86% | 73.29 | 452 / 527 |
| uterus | 93% | 1070.45 | 158 / 170 | 82% | 134.79 | 378 / 459 |
| thymus | 100% | 1790.31 | 651 / 653 | 71% | 133.19 | 432 / 605 |
| stomach | 85% | 1071.10 | 306 / 359 | 86% | 59.20 | 245 / 286 |
| bladder | 81% | 1289.48 | 17 / 21 | 89% | 154.82 | 450 / 504 |
| kidney | 100% | 3577.40 | 89 / 89 | 61% | 42.47 | 551 / 901 |
| skin | 97% | 1464.78 | 1749 / 1809 | 44% | 38.55 | 209 / 472 |
| pancreas | 45% | 262.39 | 148 / 328 | 90% | 186.29 | 161 / 178 |
| prostate | 94% | 899.95 | 231 / 245 | 7% | 2.33 | 36 / 502 |
| spleen | 100% | 3824.38 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 100% | 3713.81 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 1760.66 | 1315 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 131.39 | 43 / 45 |
| heart | 91% | 955.40 | 787 / 861 | 0% | 0 | 0 / 0 |
| ovary | 19% | 149.27 | 34 / 180 | 60% | 45.75 | 260 / 430 |
| lymph node | 0% | 0 | 0 / 0 | 76% | 43.43 | 22 / 29 |
| adrenal gland | 67% | 335.77 | 172 / 258 | 8% | 5.93 | 18 / 230 |
| muscle | 63% | 490.38 | 509 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 43% | 891.15 | 397 / 929 | 0% | 0 | 0 / 0 |
| brain | 6% | 28.42 | 152 / 2642 | 24% | 16.92 | 171 / 705 |
| liver | 7% | 37.28 | 15 / 226 | 6% | 6.29 | 26 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0014909 | Biological process | smooth muscle cell migration |
| GO_0031639 | Biological process | plasminogen activation |
| GO_0010469 | Biological process | regulation of signaling receptor activity |
| GO_0051917 | Biological process | regulation of fibrinolysis |
| GO_0051918 | Biological process | negative regulation of fibrinolysis |
| GO_0010757 | Biological process | negative regulation of plasminogen activation |
| GO_0007165 | Biological process | signal transduction |
| GO_0006935 | Biological process | chemotaxis |
| GO_0007596 | Biological process | blood coagulation |
| GO_0042730 | Biological process | fibrinolysis |
| GO_0014910 | Biological process | regulation of smooth muscle cell migration |
| GO_0030335 | Biological process | positive regulation of cell migration |
| GO_0033628 | Biological process | regulation of cell adhesion mediated by integrin |
| GO_0001666 | Biological process | response to hypoxia |
| GO_0006508 | Biological process | proteolysis |
| GO_0061041 | Biological process | regulation of wound healing |
| GO_0010755 | Biological process | regulation of plasminogen activation |
| GO_2000097 | Biological process | regulation of smooth muscle cell-matrix adhesion |
| GO_0038195 | Biological process | urokinase plasminogen activator signaling pathway |
| GO_0030155 | Biological process | regulation of cell adhesion |
| GO_0042127 | Biological process | regulation of cell population proliferation |
| GO_0005615 | Cellular component | extracellular space |
| GO_0009897 | Cellular component | external side of plasma membrane |
| GO_0005576 | Cellular component | extracellular region |
| GO_0035579 | Cellular component | specific granule membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005925 | Cellular component | focal adhesion |
| GO_0097180 | Cellular component | serine protease inhibitor complex |
| GO_0009986 | Cellular component | cell surface |
| GO_0070821 | Cellular component | tertiary granule membrane |
| GO_0098637 | Cellular component | protein complex involved in cell-matrix adhesion |
| GO_1905370 | Cellular component | serine-type endopeptidase complex |
| GO_0005515 | Molecular function | protein binding |
| GO_0004252 | Molecular function | serine-type endopeptidase activity |
| Gene name | PLAU |
| Protein name | PLAU protein Urokinase-type plasminogen activator (EC 3.4.21.73) Plasminogen activator, urokinase Urokinase-type plasminogen activator (U-plasminogen activator) (uPA) (EC 3.4.21.73) [Cleaved into: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B] |
| Synonyms | |
| Description | FUNCTION: Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. FUNCTION: Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. . |
| Accessions | ENST00000446342 Q9UEJ5 ENST00000372764.4 [P00749-1] S4R3G7 ENST00000481390.5 ENST00000446342.5 [P00749-2] P00749 E7ET40 |
