Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 14 studies | 35% ± 16% | |
| oligodendrocyte precursor cell | 12 studies | 35% ± 15% | |
| glutamatergic neuron | 10 studies | 45% ± 21% | |
| GABAergic neuron | 9 studies | 43% ± 19% | |
| macrophage | 8 studies | 25% ± 7% | |
| oligodendrocyte | 8 studies | 27% ± 10% | |
| endothelial cell | 7 studies | 29% ± 10% | |
| endothelial cell of lymphatic vessel | 7 studies | 32% ± 9% | |
| microglial cell | 6 studies | 29% ± 10% | |
| interneuron | 6 studies | 46% ± 22% | |
| neuron | 5 studies | 40% ± 19% | |
| cardiac muscle cell | 5 studies | 30% ± 8% | |
| monocyte | 5 studies | 20% ± 4% | |
| club cell | 5 studies | 34% ± 12% | |
| type I pneumocyte | 5 studies | 51% ± 6% | |
| type II pneumocyte | 5 studies | 41% ± 3% | |
| Mueller cell | 4 studies | 42% ± 10% | |
| amacrine cell | 4 studies | 50% ± 14% | |
| retina horizontal cell | 4 studies | 76% ± 13% | |
| retinal rod cell | 4 studies | 27% ± 7% | |
| ciliated cell | 4 studies | 34% ± 10% | |
| GABAergic interneuron | 3 studies | 27% ± 5% | |
| extravillous trophoblast | 3 studies | 25% ± 4% | |
| GABAergic amacrine cell | 3 studies | 41% ± 5% | |
| glycinergic amacrine cell | 3 studies | 41% ± 4% | |
| retinal cone cell | 3 studies | 50% ± 17% | |
| retinal ganglion cell | 3 studies | 42% ± 18% | |
| hepatocyte | 3 studies | 41% ± 10% | |
| neural progenitor cell | 3 studies | 21% ± 5% | |
| ependymal cell | 3 studies | 28% ± 13% | |
| epithelial cell | 3 studies | 42% ± 20% | |
| myeloid cell | 3 studies | 19% ± 1% | |
| basal cell | 3 studies | 42% ± 14% | |
| mucus secreting cell | 3 studies | 20% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 99% | 643.05 | 956 / 966 | 95% | 4.76 | 499 / 527 |
| thymus | 100% | 1986.30 | 653 / 653 | 88% | 5.23 | 534 / 605 |
| pancreas | 100% | 555.12 | 328 / 328 | 87% | 2.53 | 155 / 178 |
| lung | 98% | 537.67 | 568 / 578 | 89% | 3.03 | 1023 / 1155 |
| liver | 100% | 467.18 | 226 / 226 | 84% | 2.77 | 340 / 406 |
| brain | 97% | 356.38 | 2552 / 2642 | 87% | 2.35 | 610 / 705 |
| esophagus | 86% | 306.56 | 1241 / 1445 | 92% | 3.53 | 169 / 183 |
| bladder | 81% | 244.38 | 17 / 21 | 93% | 3.59 | 469 / 504 |
| adrenal gland | 98% | 262.41 | 253 / 258 | 68% | 2.08 | 156 / 230 |
| uterus | 75% | 192.49 | 127 / 170 | 90% | 3.11 | 411 / 459 |
| kidney | 100% | 512.35 | 89 / 89 | 61% | 1.43 | 554 / 901 |
| prostate | 91% | 505.02 | 222 / 245 | 66% | 1.24 | 332 / 502 |
| stomach | 63% | 96.94 | 227 / 359 | 89% | 4.37 | 254 / 286 |
| breast | 77% | 299.80 | 353 / 459 | 72% | 2.59 | 808 / 1118 |
| skin | 73% | 507.51 | 1324 / 1809 | 71% | 2.61 | 336 / 472 |
| ovary | 57% | 96.88 | 102 / 180 | 75% | 1.90 | 324 / 430 |
| spleen | 100% | 287.29 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.60 | 1 / 1 |
| peripheral blood | 98% | 600.06 | 909 / 929 | 0% | 0 | 0 / 0 |
| muscle | 89% | 219.25 | 715 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 2.66 | 40 / 45 |
| heart | 88% | 184.29 | 756 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 66% | 3.56 | 19 / 29 |
| adipose | 53% | 80.29 | 644 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 49% | 2.01 | 39 / 80 |
| blood vessel | 21% | 30.79 | 279 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007276 | Biological process | gamete generation |
| GO_0030522 | Biological process | intracellular receptor signaling pathway |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0000785 | Cellular component | chromatin |
| GO_0005667 | Cellular component | transcription regulator complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0004879 | Molecular function | nuclear receptor activity |
| GO_0003677 | Molecular function | DNA binding |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0034056 | Molecular function | estrogen response element binding |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0008270 | Molecular function | zinc ion binding |
| GO_0043565 | Molecular function | sequence-specific DNA binding |
| Gene name | NR6A1 |
| Protein name | Germ cell nuclear factor variant 1 (Nuclear receptor subfamily 6, group A, member 1, isoform CRA_b) Nuclear receptor subfamily 6 group A member 1 Germ cell nuclear factor (Nuclear receptor subfamily 6, group A, member 1, isoform CRA_a) Nuclear receptor subfamily 6 group A member 1 (Germ cell nuclear factor) (GCNF) (hGCNF) (Retinoid receptor-related testis-specific receptor) (RTR) (hRTR) |
| Synonyms | hCG_29220 GCNF |
| Description | FUNCTION: Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis (By similarity). . |
| Accessions | Q15406 C9JDI9 ENST00000475178.1 ENST00000373584.7 [Q15406-2] ENST00000416460.6 [Q15406-5] ENST00000487099.7 [Q15406-1] F1D8S0 F1DAM1 ENST00000344523.8 [Q15406-4] |