NIN | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	24 studies	25% ± 8%	Explore
endothelial cell	16 studies	30% ± 18%	Explore
memory B cell	15 studies	23% ± 6%	Explore
classical monocyte	15 studies	25% ± 10%	Explore
plasmacytoid dendritic cell	14 studies	33% ± 11%	Explore
CD8-positive, alpha-beta T cell	14 studies	21% ± 4%	Explore
T cell	13 studies	21% ± 7%	Explore
non-classical monocyte	13 studies	24% ± 9%	Explore
astrocyte	12 studies	36% ± 16%	Explore
glutamatergic neuron	10 studies	58% ± 25%	Explore
macrophage	10 studies	28% ± 9%	Explore
monocyte	9 studies	25% ± 8%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	23% ± 6%	Explore
naive B cell	9 studies	24% ± 4%	Explore
oligodendrocyte precursor cell	9 studies	36% ± 12%	Explore
dendritic cell	9 studies	31% ± 16%	Explore
gamma-delta T cell	9 studies	22% ± 5%	Explore
oligodendrocyte	9 studies	26% ± 7%	Explore
natural killer cell	8 studies	21% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	23% ± 7%	Explore
microglial cell	8 studies	26% ± 8%	Explore
GABAergic neuron	7 studies	47% ± 20%	Explore
CD4-positive, alpha-beta T cell	7 studies	20% ± 3%	Explore
myeloid cell	6 studies	24% ± 7%	Explore
Mueller cell	6 studies	47% ± 13%	Explore
ciliated cell	5 studies	20% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	20% ± 2%	Explore
hematopoietic precursor cell	5 studies	27% ± 9%	Explore
interneuron	5 studies	39% ± 5%	Explore
mucosal invariant T cell	5 studies	20% ± 3%	Explore
cardiac muscle cell	5 studies	26% ± 5%	Explore
retinal cone cell	5 studies	22% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	23% ± 4%	Explore
neutrophil	4 studies	25% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	17% ± 1%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	20% ± 3%	Explore
neuron	4 studies	42% ± 7%	Explore
epithelial cell	4 studies	29% ± 10%	Explore
granule cell	4 studies	42% ± 21%	Explore
pericyte	4 studies	28% ± 15%	Explore
mononuclear phagocyte	4 studies	18% ± 4%	Explore
lymphocyte	4 studies	33% ± 11%	Explore
retinal ganglion cell	4 studies	32% ± 17%	Explore
endothelial cell of lymphatic vessel	4 studies	18% ± 2%	Explore
fibroblast	4 studies	19% ± 3%	Explore
ionocyte	3 studies	26% ± 7%	Explore
conventional dendritic cell	3 studies	36% ± 17%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	26% ± 3%	Explore
plasmablast	3 studies	26% ± 8%	Explore
amacrine cell	3 studies	40% ± 23%	Explore
glycinergic amacrine cell	3 studies	32% ± 9%	Explore
basal cell	3 studies	23% ± 8%	Explore
secretory cell	3 studies	17% ± 1%	Explore
T follicular helper cell	3 studies	19% ± 3%	Explore
germinal center B cell	3 studies	25% ± 6%	Explore
leukocyte	3 studies	29% ± 7%	Explore
alveolar macrophage	3 studies	25% ± 6%	Explore
regulatory T cell	3 studies	16% ± 0%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	15 studies	38% ± 20%	Explore
peripheral blood	9 studies	21% ± 6%	Explore
eye	5 studies	21% ± 6%	Explore
lung	4 studies	19% ± 2%	Explore
heart	3 studies	20% ± 4%	Explore
adipose	3 studies	18% ± 0%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	2701.23	2632 / 2642	100%	18.93	703 / 705
breast	100%	2985.77	459 / 459	99%	17.48	1110 / 1118
prostate	100%	2442.55	245 / 245	99%	12.03	498 / 502
skin	100%	4301.78	1808 / 1809	99%	32.62	466 / 472
uterus	100%	3042.45	170 / 170	98%	12.62	450 / 459
thymus	100%	2332.26	653 / 653	97%	8.75	587 / 605
lung	100%	3436.84	578 / 578	97%	12.13	1117 / 1155
esophagus	100%	2865.45	1445 / 1445	96%	15.82	175 / 183
bladder	100%	3342.57	21 / 21	94%	9.91	475 / 504
kidney	100%	1818.39	89 / 89	92%	12.14	828 / 901
intestine	100%	2949.97	966 / 966	85%	7.08	448 / 527
stomach	100%	2704.98	359 / 359	85%	7.35	242 / 286
adrenal gland	98%	1335.34	254 / 258	85%	6.37	196 / 230
pancreas	87%	910.08	285 / 328	94%	10.03	167 / 178
ovary	100%	2613.76	180 / 180	73%	4.12	312 / 430
liver	40%	315.14	90 / 226	64%	4.60	260 / 406
adipose	100%	3379.07	1204 / 1204	0%	0	0 / 0
blood vessel	100%	3683.87	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	31.56	29 / 29
muscle	100%	2815.27	803 / 803	0%	0	0 / 0
spleen	100%	5573.90	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	15.57	45 / 45
peripheral blood	100%	9403.53	927 / 929	0%	0	0 / 0
heart	97%	2741.19	835 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	93%	12.04	74 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0050772	Biological process	positive regulation of axonogenesis
GO_0048668	Biological process	collateral sprouting
GO_0051642	Biological process	centrosome localization
GO_0010457	Biological process	centriole-centriole cohesion
GO_0090222	Biological process	centrosome-templated microtubule nucleation
GO_0008104	Biological process	protein localization
GO_0034454	Biological process	microtubule anchoring at centrosome
GO_0021540	Biological process	corpus callosum morphogenesis
GO_0021957	Biological process	corticospinal tract morphogenesis
GO_0005730	Cellular component	nucleolus
GO_0097431	Cellular component	mitotic spindle pole
GO_0097539	Cellular component	ciliary transition fiber
GO_0005886	Cellular component	plasma membrane
GO_0000922	Cellular component	spindle pole
GO_0072686	Cellular component	mitotic spindle
GO_0005813	Cellular component	centrosome
GO_0005654	Cellular component	nucleoplasm
GO_0030425	Cellular component	dendrite
GO_0005814	Cellular component	centriole
GO_0120103	Cellular component	centriolar subdistal appendage
GO_0005881	Cellular component	cytoplasmic microtubule
GO_0044295	Cellular component	axonal growth cone
GO_0000242	Cellular component	pericentriolar material
GO_0045177	Cellular component	apical part of cell
GO_0051011	Molecular function	microtubule minus-end binding
GO_0019900	Molecular function	kinase binding
GO_0005525	Molecular function	GTP binding
GO_0005509	Molecular function	calcium ion binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	NIN
Protein name	Ninein Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein) Ninein variant
Synonyms	KIAA1565
Description	FUNCTION: Centrosomal protein required in the positioning and anchorage of the microtubule minus-end in epithelial cells . May also act as a centrosome maturation factor . May play a role in microtubule nucleation, by recruiting the gamma-tubulin ring complex to the centrosome . Overexpression does not perturb nucleation or elongation of microtubules but suppresses release of microtubules . Required for centriole organization and microtubule anchoring at the mother centriole . .
Accessions	A0A0B4J215 ENST00000674030.1 E9PN67 ENST00000453196.6 ENST00000673852.1 ENST00000496749.1 A0A669KBE5 R4GN85 ENST00000389869.7 ENST00000476352.5 A0A669KBK6 A0A9L9PY96 ENST00000485005.2 ENST00000673657.1 A0A6F7YPF6 ENST00000382043.8 [Q8N4C6-11] E9PJH9 ENST00000382041.7 [Q8N4C6-1] ENST00000674061.1 ENST00000706705.1 Q8N4C6 ENST00000324330.13 [Q8N4C6-11] ENST00000530997.7 [Q8N4C6-7] A0A669KBB6 A0A9L9PXF3 ENST00000486950.5 ENST00000706706.1 C9J066 H7C162 A0A669KBI5 H9KV85 ENST00000453401.6

NIN report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review