NGRN report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0070131Biological processpositive regulation of mitochondrial translation
GO_0030182Biological processneuron differentiation
GO_0061668Biological processmitochondrial ribosome assembly
GO_0031966Cellular componentmitochondrial membrane
GO_0016604Cellular componentnuclear body
GO_0005654Cellular componentnucleoplasm
GO_0005576Cellular componentextracellular region
GO_0045171Cellular componentintercellular bridge
GO_0072686Cellular componentmitotic spindle
GO_0005739Cellular componentmitochondrion
GO_0005634Cellular componentnucleus
GO_0003723Molecular functionRNA binding
GO_0019843Molecular functionrRNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameNGRN
Protein nameNeugrin (Mesenchymal stem cell protein DSC92) (Neurite outgrowth-associated protein) (Spinal cord-derived protein FI58G)
Neugrin, neurite outgrowth associated
SynonymsFI58G
HT020
DescriptionFUNCTION: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system. .

AccessionsENST00000411845.3
ENST00000379095.5 [Q9NPE2-2]
Q9NPE2
A0A087WWE0