Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 39 studies | 37% ± 16% | |
smooth muscle cell | 23 studies | 26% ± 9% | |
pericyte | 22 studies | 29% ± 14% | |
fibroblast | 20 studies | 28% ± 13% | |
astrocyte | 19 studies | 43% ± 20% | |
endothelial cell of lymphatic vessel | 13 studies | 29% ± 14% | |
oligodendrocyte precursor cell | 13 studies | 41% ± 18% | |
glutamatergic neuron | 12 studies | 55% ± 24% | |
capillary endothelial cell | 12 studies | 25% ± 8% | |
GABAergic neuron | 11 studies | 45% ± 23% | |
epithelial cell | 11 studies | 40% ± 24% | |
oligodendrocyte | 11 studies | 32% ± 12% | |
endothelial cell of artery | 10 studies | 29% ± 5% | |
basal cell | 10 studies | 32% ± 20% | |
type I pneumocyte | 9 studies | 28% ± 8% | |
vein endothelial cell | 9 studies | 28% ± 18% | |
ciliated cell | 8 studies | 28% ± 11% | |
adipocyte | 8 studies | 29% ± 8% | |
endothelial cell of vascular tree | 8 studies | 29% ± 20% | |
neuron | 7 studies | 45% ± 15% | |
amacrine cell | 7 studies | 29% ± 14% | |
retinal ganglion cell | 7 studies | 54% ± 24% | |
respiratory goblet cell | 6 studies | 28% ± 9% | |
interneuron | 6 studies | 55% ± 25% | |
club cell | 6 studies | 30% ± 7% | |
retina horizontal cell | 6 studies | 36% ± 16% | |
Mueller cell | 6 studies | 39% ± 16% | |
type II pneumocyte | 6 studies | 25% ± 7% | |
goblet cell | 6 studies | 32% ± 26% | |
secretory cell | 5 studies | 23% ± 5% | |
retinal bipolar neuron | 5 studies | 24% ± 4% | |
microglial cell | 5 studies | 41% ± 14% | |
cardiac muscle cell | 5 studies | 34% ± 8% | |
connective tissue cell | 5 studies | 27% ± 8% | |
pancreatic A cell | 4 studies | 39% ± 22% | |
granule cell | 4 studies | 39% ± 11% | |
myofibroblast cell | 4 studies | 25% ± 11% | |
retinal cone cell | 4 studies | 23% ± 10% | |
retinal pigment epithelial cell | 4 studies | 43% ± 22% | |
mesothelial cell | 4 studies | 28% ± 4% | |
OFF-bipolar cell | 4 studies | 34% ± 10% | |
ON-bipolar cell | 4 studies | 36% ± 11% | |
hepatocyte | 4 studies | 34% ± 19% | |
muscle cell | 4 studies | 36% ± 21% | |
enteroendocrine cell | 4 studies | 23% ± 7% | |
ionocyte | 3 studies | 24% ± 5% | |
glomerular endothelial cell | 3 studies | 26% ± 4% | |
GABAergic interneuron | 3 studies | 42% ± 1% | |
glial cell | 3 studies | 30% ± 6% | |
squamous epithelial cell | 3 studies | 41% ± 23% | |
lymphocyte | 3 studies | 18% ± 3% | |
GABAergic amacrine cell | 3 studies | 38% ± 17% | |
glycinergic amacrine cell | 3 studies | 31% ± 10% | |
retinal rod cell | 3 studies | 28% ± 6% | |
rod bipolar cell | 3 studies | 40% ± 18% | |
pancreatic ductal cell | 3 studies | 45% ± 25% | |
ependymal cell | 3 studies | 52% ± 18% | |
transit amplifying cell | 3 studies | 43% ± 36% | |
keratinocyte | 3 studies | 23% ± 5% | |
mucus secreting cell | 3 studies | 28% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 8823.45 | 180 / 180 | 100% | 27.46 | 430 / 430 |
lung | 100% | 10117.99 | 577 / 578 | 100% | 34.89 | 1154 / 1155 |
breast | 100% | 10878.88 | 459 / 459 | 100% | 35.02 | 1113 / 1118 |
esophagus | 100% | 15970.26 | 1445 / 1445 | 99% | 46.65 | 182 / 183 |
brain | 100% | 11517.08 | 2630 / 2642 | 100% | 39.05 | 703 / 705 |
intestine | 100% | 12262.56 | 965 / 966 | 99% | 28.13 | 520 / 527 |
uterus | 100% | 12093.66 | 170 / 170 | 98% | 28.28 | 451 / 459 |
bladder | 100% | 13818.38 | 21 / 21 | 98% | 26.62 | 495 / 504 |
prostate | 100% | 9139.35 | 244 / 245 | 99% | 24.91 | 495 / 502 |
stomach | 100% | 10384.65 | 359 / 359 | 98% | 29.87 | 280 / 286 |
kidney | 100% | 7406.80 | 89 / 89 | 98% | 26.59 | 880 / 901 |
thymus | 100% | 10829.86 | 652 / 653 | 96% | 32.33 | 581 / 605 |
pancreas | 97% | 4968.36 | 318 / 328 | 99% | 28.70 | 176 / 178 |
adrenal gland | 100% | 10060.74 | 258 / 258 | 96% | 21.93 | 220 / 230 |
skin | 100% | 14226.49 | 1808 / 1809 | 94% | 26.58 | 446 / 472 |
liver | 91% | 3379.43 | 206 / 226 | 86% | 11.72 | 351 / 406 |
blood vessel | 100% | 18575.41 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 13648.95 | 803 / 803 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 11.04 | 1 / 1 |
adipose | 100% | 11668.32 | 1203 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 25.75 | 44 / 45 |
heart | 97% | 9015.62 | 834 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 90% | 15.32 | 72 / 80 |
spleen | 84% | 3119.25 | 203 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 2% | 57.40 | 19 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030838 | Biological process | positive regulation of actin filament polymerization |
GO_0010592 | Biological process | positive regulation of lamellipodium assembly |
GO_0030031 | Biological process | cell projection assembly |
GO_0048812 | Biological process | neuron projection morphogenesis |
GO_0016601 | Biological process | Rac protein signal transduction |
GO_0007417 | Biological process | central nervous system development |
GO_0006915 | Biological process | apoptotic process |
GO_2000601 | Biological process | positive regulation of Arp2/3 complex-mediated actin nucleation |
GO_0000902 | Biological process | cell morphogenesis |
GO_0030866 | Biological process | cortical actin cytoskeleton organization |
GO_0016477 | Biological process | cell migration |
GO_0001726 | Cellular component | ruffle |
GO_0031941 | Cellular component | filamentous actin |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005925 | Cellular component | focal adhesion |
GO_0031258 | Cellular component | lamellipodium membrane |
GO_0005829 | Cellular component | cytosol |
GO_0030027 | Cellular component | lamellipodium |
GO_0031209 | Cellular component | SCAR complex |
GO_0031267 | Molecular function | small GTPase binding |
GO_0005515 | Molecular function | protein binding |
Gene name | NCKAP1 |
Protein name | Nck-associated protein 1 (NAP 1) (Membrane-associated protein HEM-2) (p125Nap1) Nck-associated protein 1 |
Synonyms | KIAA0587 HEM2 NAP1 |
Description | FUNCTION: Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes. . |
Accessions | ENST00000361354.9 [Q9Y2A7-1] ENST00000360982.2 [Q9Y2A7-2] ENST00000703824.1 Q9Y2A7 A0A994J4I5 A0A994J6K9 ENST00000703825.1 |