Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 11 studies | 21% ± 6% | |
ciliated cell | 9 studies | 25% ± 8% | |
oligodendrocyte | 9 studies | 27% ± 10% | |
natural killer cell | 7 studies | 19% ± 2% | |
epithelial cell | 5 studies | 37% ± 12% | |
fibroblast | 5 studies | 18% ± 3% | |
macrophage | 5 studies | 19% ± 2% | |
classical monocyte | 4 studies | 22% ± 6% | |
CD16-positive, CD56-dim natural killer cell, human | 4 studies | 18% ± 1% | |
CD16-negative, CD56-bright natural killer cell, human | 4 studies | 17% ± 2% | |
basal cell | 4 studies | 25% ± 5% | |
endothelial cell of lymphatic vessel | 4 studies | 18% ± 1% | |
naive B cell | 3 studies | 17% ± 2% | |
hematopoietic precursor cell | 3 studies | 21% ± 4% | |
B cell | 3 studies | 19% ± 4% | |
myeloid cell | 3 studies | 22% ± 4% | |
lymphocyte | 3 studies | 19% ± 5% | |
secretory cell | 3 studies | 19% ± 4% | |
glutamatergic neuron | 3 studies | 30% ± 12% | |
neuron | 3 studies | 26% ± 6% | |
plasmacytoid dendritic cell | 3 studies | 25% ± 7% | |
astrocyte | 3 studies | 29% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 3864.05 | 21 / 21 | 100% | 10.23 | 504 / 504 |
esophagus | 100% | 3882.82 | 1445 / 1445 | 100% | 13.64 | 183 / 183 |
intestine | 100% | 4786.72 | 966 / 966 | 100% | 9.69 | 527 / 527 |
prostate | 100% | 4169.00 | 245 / 245 | 100% | 11.20 | 502 / 502 |
stomach | 100% | 3659.25 | 359 / 359 | 100% | 9.81 | 286 / 286 |
breast | 100% | 4520.23 | 459 / 459 | 100% | 11.98 | 1117 / 1118 |
uterus | 100% | 4895.71 | 170 / 170 | 100% | 11.59 | 458 / 459 |
ovary | 100% | 4934.00 | 180 / 180 | 100% | 8.37 | 429 / 430 |
lung | 100% | 3939.58 | 577 / 578 | 100% | 10.89 | 1154 / 1155 |
thymus | 100% | 4641.17 | 653 / 653 | 100% | 12.68 | 603 / 605 |
brain | 100% | 2834.84 | 2633 / 2642 | 100% | 10.88 | 705 / 705 |
pancreas | 100% | 3291.10 | 328 / 328 | 99% | 9.78 | 177 / 178 |
kidney | 100% | 3330.37 | 89 / 89 | 99% | 11.56 | 891 / 901 |
skin | 100% | 4836.09 | 1809 / 1809 | 99% | 10.51 | 466 / 472 |
adrenal gland | 100% | 3643.50 | 258 / 258 | 98% | 6.32 | 225 / 230 |
liver | 100% | 1914.12 | 226 / 226 | 87% | 4.31 | 355 / 406 |
adipose | 100% | 4348.72 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3522.12 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 10.21 | 29 / 29 |
spleen | 100% | 4968.29 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 10.40 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.39 | 1 / 1 |
muscle | 100% | 1825.48 | 800 / 803 | 0% | 0 | 0 / 0 |
heart | 100% | 2386.43 | 857 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 93% | 2202.50 | 864 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 93% | 8.61 | 74 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006406 | Biological process | mRNA export from nucleus |
GO_0051607 | Biological process | defense response to virus |
GO_0006408 | Biological process | snRNA export from nucleus |
GO_0042789 | Biological process | mRNA transcription by RNA polymerase II |
GO_0006370 | Biological process | 7-methylguanosine mRNA capping |
GO_0035194 | Biological process | regulatory ncRNA-mediated post-transcriptional gene silencing |
GO_0005846 | Cellular component | nuclear cap binding complex |
GO_0016607 | Cellular component | nuclear speck |
GO_0034518 | Cellular component | RNA cap binding complex |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0000339 | Molecular function | RNA cap binding |
GO_0000340 | Molecular function | RNA 7-methylguanosine cap binding |
GO_0005515 | Molecular function | protein binding |
GO_0003729 | Molecular function | mRNA binding |
GO_0003723 | Molecular function | RNA binding |
Gene name | NCBP3 |
Protein name | Nuclear cap-binding protein subunit 3 Nuclear cap binding subunit 3 Nuclear cap-binding protein subunit 3 (Protein ELG) |
Synonyms | C17orf85 |
Description | FUNCTION: Associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the NCBP3 activity is critical to inhibit virus growth . . |
Accessions | Q53F19 ENST00000389005.6 [Q53F19-1] ENST00000574911.5 K7EQA5 K7ELP6 L0R6D6 ENST00000576523.1 |