nuclear cap binding complex

I. Literature review

[source]
Namenuclear cap binding complex
IDGO_0005846
collection_id

Cellular component

Exact synonym

nuclear CBC

Description

A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export.

Related synonym

CBC

Comment

Note that this complex can be found in the cytoplasm as well as the nucleus.

External URL
Genes