MTIF3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	19 studies	26% ± 11%	Explore
endothelial cell of lymphatic vessel	14 studies	24% ± 9%	Explore
ciliated cell	11 studies	32% ± 15%	Explore
macrophage	11 studies	22% ± 8%	Explore
B cell	11 studies	19% ± 5%	Explore
smooth muscle cell	10 studies	18% ± 3%	Explore
classical monocyte	9 studies	23% ± 9%	Explore
fibroblast	9 studies	24% ± 11%	Explore
conventional dendritic cell	8 studies	25% ± 11%	Explore
capillary endothelial cell	8 studies	18% ± 2%	Explore
pericyte	8 studies	19% ± 4%	Explore
epithelial cell	8 studies	38% ± 17%	Explore
regulatory T cell	8 studies	18% ± 2%	Explore
non-classical monocyte	7 studies	23% ± 7%	Explore
plasma cell	7 studies	30% ± 11%	Explore
plasmacytoid dendritic cell	7 studies	24% ± 7%	Explore
basal cell	6 studies	31% ± 13%	Explore
retinal rod cell	6 studies	30% ± 10%	Explore
natural killer cell	5 studies	18% ± 1%	Explore
epithelial cell of proximal tubule	5 studies	27% ± 7%	Explore
myofibroblast cell	5 studies	18% ± 1%	Explore
endothelial cell of vascular tree	5 studies	19% ± 3%	Explore
astrocyte	5 studies	27% ± 6%	Explore
retina horizontal cell	5 studies	34% ± 11%	Explore
CD4-positive, alpha-beta T cell	4 studies	19% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
kidney loop of Henle epithelial cell	4 studies	23% ± 7%	Explore
goblet cell	4 studies	26% ± 11%	Explore
vein endothelial cell	4 studies	22% ± 3%	Explore
memory B cell	4 studies	17% ± 2%	Explore
brush cell	4 studies	31% ± 14%	Explore
retinal cone cell	4 studies	44% ± 18%	Explore
monocyte	4 studies	20% ± 5%	Explore
lymphocyte	4 studies	20% ± 5%	Explore
Mueller cell	4 studies	29% ± 11%	Explore
abnormal cell	4 studies	18% ± 1%	Explore
adipocyte	4 studies	19% ± 2%	Explore
microglial cell	4 studies	19% ± 4%	Explore
oligodendrocyte	4 studies	24% ± 4%	Explore
pancreatic A cell	3 studies	29% ± 3%	Explore
type B pancreatic cell	3 studies	37% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	17% ± 2%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	17% ± 0%	Explore
endothelial cell of artery	3 studies	21% ± 5%	Explore
leukocyte	3 studies	20% ± 5%	Explore
myeloid cell	3 studies	29% ± 10%	Explore
club cell	3 studies	25% ± 11%	Explore
enterocyte	3 studies	20% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	18% ± 2%	Explore
precursor B cell	3 studies	30% ± 9%	Explore
pro-B cell	3 studies	29% ± 4%	Explore
amacrine cell	3 studies	33% ± 12%	Explore
OFF-bipolar cell	3 studies	21% ± 2%	Explore
ON-bipolar cell	3 studies	19% ± 1%	Explore
rod bipolar cell	3 studies	23% ± 1%	Explore
secretory cell	3 studies	25% ± 13%	Explore
cardiac muscle cell	3 studies	18% ± 2%	Explore
neuron	3 studies	29% ± 9%	Explore
GABAergic neuron	3 studies	37% ± 4%	Explore
glutamatergic neuron	3 studies	46% ± 6%	Explore
oligodendrocyte precursor cell	3 studies	23% ± 5%	Explore
CD8-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore
enteroendocrine cell	3 studies	28% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	19% ± 3%	Explore
gamma-delta T cell	3 studies	25% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	18% ± 2%	Explore
hepatocyte	3 studies	42% ± 23%	Explore
connective tissue cell	3 studies	19% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	8 studies	20% ± 6%	Explore
eye	8 studies	26% ± 11%	Explore
lung	6 studies	30% ± 9%	Explore
kidney	5 studies	18% ± 4%	Explore
intestine	5 studies	21% ± 8%	Explore
brain	5 studies	31% ± 9%	Explore
liver	5 studies	24% ± 16%	Explore
pancreas	3 studies	33% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	1821.05	21 / 21	100%	59.60	504 / 504
esophagus	100%	1785.36	1445 / 1445	100%	44.69	183 / 183
liver	100%	1322.71	226 / 226	100%	42.99	406 / 406
ovary	100%	1784.79	180 / 180	100%	39.16	430 / 430
pancreas	100%	1416.10	328 / 328	100%	57.28	178 / 178
prostate	100%	2215.90	245 / 245	100%	66.66	502 / 502
stomach	100%	1782.22	359 / 359	100%	73.96	286 / 286
uterus	100%	1774.50	170 / 170	100%	48.50	459 / 459
brain	100%	1853.17	2640 / 2642	100%	48.76	705 / 705
breast	100%	2689.55	459 / 459	100%	63.13	1117 / 1118
kidney	100%	2456.06	89 / 89	100%	56.66	900 / 901
thymus	100%	1957.18	653 / 653	100%	56.94	604 / 605
intestine	100%	2144.02	966 / 966	100%	76.85	526 / 527
lung	100%	1540.56	576 / 578	100%	41.02	1155 / 1155
adrenal gland	100%	2471.38	258 / 258	100%	60.22	229 / 230
skin	100%	1568.95	1808 / 1809	100%	45.22	470 / 472
adipose	100%	2869.02	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	51.44	29 / 29
muscle	100%	2551.13	803 / 803	0%	0	0 / 0
spleen	100%	2292.90	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	41.91	45 / 45
ureter	0%	0	0 / 0	100%	42.81	1 / 1
blood vessel	100%	1602.16	1332 / 1335	0%	0	0 / 0
heart	99%	3450.92	856 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	96%	36.49	77 / 80
peripheral blood	88%	978.82	818 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0070124	Biological process	mitochondrial translational initiation
GO_0032790	Biological process	ribosome disassembly
GO_0005739	Cellular component	mitochondrion
GO_0043022	Molecular function	ribosome binding
GO_0003743	Molecular function	translation initiation factor activity
GO_0008135	Molecular function	translation factor activity, RNA binding
GO_0043024	Molecular function	ribosomal small subunit binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	MTIF3
Protein name	Translation initiation factor IF-3, mitochondrial (IF-3(Mt)) (IF-3Mt) (IF3(mt)) (IF3mt)
Synonyms	DC38
Description	FUNCTION: IF-3 binds to the 28S ribosomal subunit and shifts the equilibrium between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. .
Accessions	Q9H2K0 ENST00000381116.5 ENST00000381120.8 ENST00000405591.3

MTIF3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review