MEIS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045638Biological processnegative regulation of myeloid cell differentiation
GO_0001525Biological processangiogenesis
GO_0030097Biological processhemopoiesis
GO_0061049Biological processcell growth involved in cardiac muscle cell development
GO_0009887Biological processanimal organ morphogenesis
GO_0001654Biological processeye development
GO_0035855Biological processmegakaryocyte development
GO_0060216Biological processdefinitive hemopoiesis
GO_0009880Biological processembryonic pattern specification
GO_0045665Biological processnegative regulation of neuron differentiation
GO_0007420Biological processbrain development
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0002089Biological processlens morphogenesis in camera-type eye
GO_0007626Biological processlocomotory behavior
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005667Cellular componenttranscription regulator complex
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0003682Molecular functionchromatin binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMEIS1
Protein nameMeis homeobox 1 (Meis1, myeloid ecotropic viral integration site 1 homolog (Mouse), isoform CRA_b)
Meis homeobox 1
Homeobox protein Meis1
Uncharacterized protein MEIS1
SynonymshCG_1818196
DescriptionFUNCTION: Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias. .

AccessionsU3KPR8
ENST00000488550.5
ENST00000272369.14 [O00470-1]
Q53R57
E9PDC4
ENST00000437869.1
ENST00000560281.6
Q53RD5
O00470
ENST00000495021.6
H0YNY8
ENST00000398506.6 [O00470-2]
F5GYS8