MAP4K5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0035556Biological processintracellular signal transduction
GO_0006468Biological processprotein phosphorylation
GO_0000165Biological processMAPK cascade
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0004674Molecular functionprotein serine/threonine kinase activity
GO_0106310Molecular functionprotein serine kinase activity
GO_0005515Molecular functionprotein binding
GO_0008349Molecular functionMAP kinase kinase kinase kinase activity
GO_0005524Molecular functionATP binding
GO_0004672Molecular functionprotein kinase activity

IV. Literature review

[source]
Gene nameMAP4K5
Protein namenon-specific serine/threonine protein kinase (EC 2.7.11.1)
Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)
Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1)
Mitogen-activated protein kinase kinase kinase kinase 5
Synonyms
DescriptionFUNCTION: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. .

FUNCTION: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. .

FUNCTION: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. .

AccessionsENST00000554091.5
ENST00000013125.9
A0A804HIS2
G3V4Q4
G3V4T8
G3V5C6
ENST00000555216.5
ENST00000682126.1
ENST00000557390.6
Q9Y4K4