Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 24 studies | 42% ± 20% | |
| astrocyte | 18 studies | 42% ± 19% | |
| oligodendrocyte | 14 studies | 36% ± 14% | |
| microglial cell | 14 studies | 42% ± 13% | |
| glutamatergic neuron | 13 studies | 52% ± 24% | |
| oligodendrocyte precursor cell | 13 studies | 45% ± 20% | |
| fibroblast | 13 studies | 41% ± 15% | |
| GABAergic neuron | 11 studies | 51% ± 24% | |
| pericyte | 11 studies | 40% ± 17% | |
| smooth muscle cell | 11 studies | 35% ± 11% | |
| macrophage | 10 studies | 35% ± 15% | |
| epithelial cell | 8 studies | 40% ± 18% | |
| adipocyte | 8 studies | 45% ± 10% | |
| interneuron | 7 studies | 58% ± 26% | |
| neuron | 6 studies | 50% ± 20% | |
| ciliated cell | 6 studies | 27% ± 11% | |
| cardiac muscle cell | 5 studies | 60% ± 16% | |
| dendritic cell | 5 studies | 22% ± 6% | |
| myeloid cell | 5 studies | 37% ± 15% | |
| monocyte | 5 studies | 27% ± 8% | |
| type I pneumocyte | 5 studies | 33% ± 10% | |
| type II pneumocyte | 5 studies | 32% ± 6% | |
| granule cell | 4 studies | 49% ± 7% | |
| mesothelial cell | 4 studies | 29% ± 10% | |
| amacrine cell | 4 studies | 42% ± 19% | |
| retina horizontal cell | 4 studies | 41% ± 18% | |
| retinal cone cell | 4 studies | 59% ± 20% | |
| retinal rod cell | 4 studies | 56% ± 13% | |
| endothelial cell of lymphatic vessel | 4 studies | 33% ± 8% | |
| club cell | 4 studies | 36% ± 9% | |
| hepatic stellate cell | 3 studies | 42% ± 17% | |
| GABAergic interneuron | 3 studies | 53% ± 2% | |
| progenitor cell | 3 studies | 33% ± 7% | |
| endothelial cell of artery | 3 studies | 22% ± 1% | |
| plasma cell | 3 studies | 32% ± 10% | |
| GABAergic amacrine cell | 3 studies | 50% ± 16% | |
| Mueller cell | 3 studies | 43% ± 15% | |
| glycinergic amacrine cell | 3 studies | 41% ± 11% | |
| retinal ganglion cell | 3 studies | 52% ± 18% | |
| chondrocyte | 3 studies | 33% ± 9% | |
| endothelial cell of vascular tree | 3 studies | 45% ± 25% | |
| cholangiocyte | 3 studies | 59% ± 14% | |
| hepatocyte | 3 studies | 48% ± 21% | |
| retinal pigment epithelial cell | 3 studies | 45% ± 28% | |
| neural progenitor cell | 3 studies | 37% ± 14% | |
| connective tissue cell | 3 studies | 31% ± 6% | |
| ependymal cell | 3 studies | 51% ± 17% | |
| mast cell | 3 studies | 28% ± 6% | |
| T cell | 3 studies | 18% ± 2% | |
| alveolar macrophage | 3 studies | 42% ± 8% | |
| myofibroblast cell | 3 studies | 35% ± 17% | |
| respiratory goblet cell | 3 studies | 33% ± 11% | |
| muscle cell | 3 studies | 49% ± 28% | |
| basal cell | 3 studies | 42% ± 24% | |
| kidney distal convoluted tubule epithelial cell | 3 studies | 40% ± 17% | |
| renal alpha-intercalated cell | 3 studies | 50% ± 24% | |
| mucus secreting cell | 3 studies | 25% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2205.46 | 1445 / 1445 | 100% | 27.72 | 183 / 183 |
| lung | 100% | 2712.99 | 578 / 578 | 100% | 24.76 | 1155 / 1155 |
| ovary | 100% | 3657.84 | 180 / 180 | 100% | 18.49 | 429 / 430 |
| breast | 100% | 2982.90 | 459 / 459 | 99% | 28.03 | 1112 / 1118 |
| brain | 99% | 1999.28 | 2624 / 2642 | 100% | 24.95 | 702 / 705 |
| prostate | 100% | 2273.64 | 244 / 245 | 99% | 24.52 | 497 / 502 |
| bladder | 100% | 2648.90 | 21 / 21 | 98% | 23.66 | 496 / 504 |
| pancreas | 99% | 1237.21 | 325 / 328 | 99% | 20.27 | 176 / 178 |
| thymus | 100% | 2781.12 | 653 / 653 | 98% | 22.15 | 591 / 605 |
| adrenal gland | 100% | 2756.40 | 258 / 258 | 97% | 15.16 | 224 / 230 |
| uterus | 100% | 3044.49 | 170 / 170 | 97% | 19.00 | 447 / 459 |
| kidney | 100% | 2157.29 | 89 / 89 | 97% | 17.29 | 876 / 901 |
| intestine | 100% | 2557.10 | 966 / 966 | 97% | 20.63 | 512 / 527 |
| stomach | 100% | 3201.94 | 359 / 359 | 97% | 22.65 | 277 / 286 |
| skin | 100% | 3043.48 | 1808 / 1809 | 92% | 17.13 | 436 / 472 |
| liver | 100% | 1102.53 | 225 / 226 | 90% | 14.36 | 364 / 406 |
| blood vessel | 100% | 3070.56 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 3434.80 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1603.39 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.99 | 1 / 1 |
| adipose | 100% | 2990.54 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| heart | 99% | 2068.37 | 850 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 12.66 | 43 / 45 |
| eye | 0% | 0 | 0 / 0 | 66% | 10.41 | 53 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 31% | 1.97 | 9 / 29 |
| peripheral blood | 17% | 131.39 | 158 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007254 | Biological process | JNK cascade |
| GO_0009411 | Biological process | response to UV |
| GO_0006468 | Biological process | protein phosphorylation |
| GO_0035556 | Biological process | intracellular signal transduction |
| GO_0034612 | Biological process | response to tumor necrosis factor |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0004674 | Molecular function | protein serine/threonine kinase activity |
| GO_0106310 | Molecular function | protein serine kinase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008349 | Molecular function | MAP kinase kinase kinase kinase activity |
| GO_0005524 | Molecular function | ATP binding |
| GO_0004672 | Molecular function | protein kinase activity |
| Gene name | MAP4K3 |
| Protein name | Uncharacterized protein MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) non-specific serine/threonine protein kinase (EC 2.7.11.1) |
| Synonyms | RAB8IPL1 |
| Description | FUNCTION: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. . FUNCTION: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. . |
| Accessions | F8WAZ1 F8WBC3 ENST00000437545.5 Q8IVH8 H7C1A4 V9GY95 Q53RV1 ENST00000429397.5 ENST00000341681.9 [Q8IVH8-3] F5H5A3 ENST00000263881.8 [Q8IVH8-1] ENST00000437968.1 ENST00000484274.1 ENST00000414968.1 |