MAP4K3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007254Biological processJNK cascade
GO_0009411Biological processresponse to UV
GO_0006468Biological processprotein phosphorylation
GO_0035556Biological processintracellular signal transduction
GO_0034612Biological processresponse to tumor necrosis factor
GO_0005737Cellular componentcytoplasm
GO_0004674Molecular functionprotein serine/threonine kinase activity
GO_0106310Molecular functionprotein serine kinase activity
GO_0005515Molecular functionprotein binding
GO_0008349Molecular functionMAP kinase kinase kinase kinase activity
GO_0005524Molecular functionATP binding
GO_0004672Molecular functionprotein kinase activity

IV. Literature review

[source]
Gene nameMAP4K3
Protein nameUncharacterized protein MAP4K3
Mitogen-activated protein kinase kinase kinase kinase 3
Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)
Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1)
non-specific serine/threonine protein kinase (EC 2.7.11.1)
SynonymsRAB8IPL1
DescriptionFUNCTION: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. .

FUNCTION: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. .

AccessionsF8WAZ1
F8WBC3
ENST00000437545.5
Q8IVH8
H7C1A4
V9GY95
Q53RV1
ENST00000429397.5
ENST00000341681.9 [Q8IVH8-3]
F5H5A3
ENST00000263881.8 [Q8IVH8-1]
ENST00000437968.1
ENST00000484274.1
ENST00000414968.1