LSM10 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	20 studies	27% ± 7%	Explore
natural killer cell	18 studies	19% ± 3%	Explore
memory B cell	16 studies	23% ± 6%	Explore
naive B cell	15 studies	26% ± 5%	Explore
non-classical monocyte	15 studies	29% ± 13%	Explore
classical monocyte	13 studies	29% ± 11%	Explore
plasmacytoid dendritic cell	13 studies	30% ± 10%	Explore
CD8-positive, alpha-beta T cell	12 studies	18% ± 2%	Explore
conventional dendritic cell	11 studies	28% ± 14%	Explore
plasma cell	10 studies	31% ± 12%	Explore
macrophage	10 studies	24% ± 9%	Explore
monocyte	10 studies	20% ± 4%	Explore
regulatory T cell	9 studies	20% ± 2%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	20% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	20% ± 4%	Explore
gamma-delta T cell	8 studies	22% ± 8%	Explore
mature NK T cell	6 studies	20% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	19% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	19% ± 1%	Explore
CD4-positive, alpha-beta T cell	5 studies	21% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	20% ± 3%	Explore
myeloid cell	5 studies	25% ± 10%	Explore
plasmablast	4 studies	40% ± 19%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	20% ± 3%	Explore
epithelial cell	4 studies	32% ± 10%	Explore
immature B cell	4 studies	31% ± 10%	Explore
endothelial cell	4 studies	23% ± 5%	Explore
dendritic cell	4 studies	38% ± 18%	Explore
mucosal invariant T cell	4 studies	17% ± 3%	Explore
pancreatic A cell	3 studies	24% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	17% ± 2%	Explore
hematopoietic precursor cell	3 studies	23% ± 4%	Explore
IgG plasma cell	3 studies	17% ± 2%	Explore
smooth muscle cell	3 studies	17% ± 1%	Explore
precursor B cell	3 studies	28% ± 11%	Explore
fibroblast	3 studies	30% ± 9%	Explore
germinal center B cell	3 studies	41% ± 5%	Explore
exhausted T cell	3 studies	19% ± 1%	Explore
intermediate monocyte	3 studies	36% ± 16%	Explore
glutamatergic neuron	3 studies	22% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	18% ± 3%	Explore
abnormal cell	3 studies	27% ± 4%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	18% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	12 studies	21% ± 5%	Explore
lung	5 studies	21% ± 4%	Explore
brain	4 studies	18% ± 2%	Explore
lymph node	3 studies	20% ± 4%	Explore
liver	3 studies	24% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	938.66	226 / 226	100%	45.10	406 / 406
ovary	100%	1043.24	180 / 180	100%	62.74	430 / 430
esophagus	100%	1413.75	1444 / 1445	100%	35.71	183 / 183
skin	100%	1146.20	1807 / 1809	100%	88.34	472 / 472
brain	100%	1267.97	2639 / 2642	100%	73.80	705 / 705
thymus	100%	1172.49	652 / 653	100%	62.88	605 / 605
uterus	100%	1237.09	170 / 170	100%	62.81	458 / 459
stomach	100%	1096.40	359 / 359	100%	45.67	285 / 286
prostate	100%	1477.83	245 / 245	99%	58.43	499 / 502
intestine	100%	1638.18	966 / 966	99%	49.68	522 / 527
kidney	100%	1277.72	89 / 89	99%	36.14	890 / 901
breast	100%	1176.87	459 / 459	99%	57.34	1104 / 1118
lung	99%	1114.68	573 / 578	100%	55.24	1150 / 1155
adrenal gland	100%	1058.29	258 / 258	99%	45.78	227 / 230
bladder	100%	1507.81	21 / 21	99%	57.93	497 / 504
pancreas	98%	562.87	323 / 328	99%	50.97	177 / 178
adipose	100%	1234.45	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	57.69	80 / 80
lymph node	0%	0	0 / 0	100%	157.58	29 / 29
muscle	100%	3207.47	803 / 803	0%	0	0 / 0
spleen	100%	1884.31	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	52.08	45 / 45
ureter	0%	0	0 / 0	100%	62.46	1 / 1
blood vessel	100%	1198.01	1330 / 1335	0%	0	0 / 0
peripheral blood	100%	2082.70	925 / 929	0%	0	0 / 0
heart	99%	1572.43	850 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_1900087	Biological process	positive regulation of G1/S transition of mitotic cell cycle
GO_0006398	Biological process	mRNA 3'-end processing by stem-loop binding and cleavage
GO_0008380	Biological process	RNA splicing
GO_0015030	Cellular component	Cajal body
GO_0005683	Cellular component	U7 snRNP
GO_0071254	Cellular component	cytoplasmic U snRNP body
GO_0016604	Cellular component	nuclear body
GO_0005654	Cellular component	nucleoplasm
GO_0071209	Molecular function	U7 snRNA binding
GO_0005515	Molecular function	protein binding
GO_0071208	Molecular function	histone pre-mRNA DCP binding

IV. Literature review

[source]

Gene name	LSM10
Protein name	U7 snRNA-associated Sm-like protein LSm10
Synonyms
Description	FUNCTION: Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. .
Accessions	ENST00000315732.3 Q969L4

LSM10 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review