LMO4 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	37 studies	36% ± 17%	Explore
mast cell	26 studies	48% ± 19%	Explore
smooth muscle cell	23 studies	34% ± 19%	Explore
pericyte	21 studies	30% ± 14%	Explore
natural killer cell	19 studies	25% ± 7%	Explore
endothelial cell	14 studies	28% ± 12%	Explore
myofibroblast cell	14 studies	34% ± 17%	Explore
connective tissue cell	14 studies	34% ± 16%	Explore
macrophage	13 studies	19% ± 6%	Explore
basal cell	13 studies	49% ± 14%	Explore
astrocyte	13 studies	32% ± 16%	Explore
oligodendrocyte precursor cell	11 studies	30% ± 13%	Explore
B cell	10 studies	21% ± 4%	Explore
plasma cell	10 studies	35% ± 14%	Explore
epithelial cell	10 studies	41% ± 22%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	24% ± 7%	Explore
glutamatergic neuron	10 studies	58% ± 22%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	22% ± 7%	Explore
mesothelial cell	9 studies	33% ± 15%	Explore
club cell	8 studies	34% ± 15%	Explore
plasmacytoid dendritic cell	8 studies	24% ± 7%	Explore
T cell	7 studies	22% ± 6%	Explore
non-classical monocyte	7 studies	29% ± 11%	Explore
conventional dendritic cell	7 studies	32% ± 15%	Explore
neuron	7 studies	33% ± 15%	Explore
microglial cell	7 studies	23% ± 7%	Explore
adipocyte	7 studies	32% ± 20%	Explore
respiratory goblet cell	6 studies	35% ± 4%	Explore
classical monocyte	6 studies	26% ± 10%	Explore
abnormal cell	6 studies	26% ± 8%	Explore
innate lymphoid cell	6 studies	23% ± 5%	Explore
type I pneumocyte	5 studies	21% ± 6%	Explore
ionocyte	5 studies	28% ± 4%	Explore
secretory cell	5 studies	41% ± 17%	Explore
memory B cell	5 studies	18% ± 3%	Explore
amacrine cell	5 studies	38% ± 14%	Explore
GABAergic neuron	5 studies	32% ± 9%	Explore
interneuron	5 studies	30% ± 13%	Explore
oligodendrocyte	5 studies	21% ± 7%	Explore
CD8-positive, alpha-beta T cell	4 studies	17% ± 3%	Explore
mature NK T cell	4 studies	21% ± 6%	Explore
plasmablast	4 studies	36% ± 18%	Explore
progenitor cell	4 studies	34% ± 10%	Explore
leukocyte	4 studies	27% ± 6%	Explore
retinal bipolar neuron	4 studies	40% ± 15%	Explore
ON-bipolar cell	4 studies	30% ± 11%	Explore
GABAergic amacrine cell	4 studies	34% ± 5%	Explore
myeloid cell	4 studies	30% ± 14%	Explore
ciliated cell	4 studies	50% ± 10%	Explore
retina horizontal cell	4 studies	32% ± 14%	Explore
retinal cone cell	4 studies	31% ± 8%	Explore
monocyte	4 studies	25% ± 12%	Explore
adventitial cell	4 studies	20% ± 6%	Explore
granulocyte	4 studies	34% ± 19%	Explore
duct epithelial cell	3 studies	46% ± 4%	Explore
CD4-positive, alpha-beta T cell	3 studies	19% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	18% ± 1%	Explore
hematopoietic precursor cell	3 studies	29% ± 11%	Explore
enterocyte	3 studies	25% ± 5%	Explore
goblet cell	3 studies	25% ± 7%	Explore
intestinal crypt stem cell	3 studies	21% ± 5%	Explore
IgG plasma cell	3 studies	19% ± 3%	Explore
transit amplifying cell	3 studies	23% ± 4%	Explore
extravillous trophoblast	3 studies	60% ± 7%	Explore
placental villous trophoblast	3 studies	71% ± 8%	Explore
pro-B cell	3 studies	23% ± 3%	Explore
alveolar macrophage	3 studies	18% ± 2%	Explore
serous secreting cell	3 studies	37% ± 2%	Explore
glycinergic amacrine cell	3 studies	21% ± 7%	Explore
rod bipolar cell	3 studies	37% ± 13%	Explore
CD4-positive helper T cell	3 studies	22% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	25% ± 3%	Explore
myoepithelial cell	3 studies	36% ± 25%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	38% ± 3%	Explore
glial cell	3 studies	37% ± 23%	Explore
group 3 innate lymphoid cell	3 studies	29% ± 16%	Explore
melanocyte	3 studies	21% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	13 studies	31% ± 16%	Explore
brain	13 studies	35% ± 19%	Explore
intestine	6 studies	36% ± 16%	Explore
eye	5 studies	26% ± 8%	Explore
peripheral blood	4 studies	31% ± 7%	Explore
placenta	4 studies	40% ± 17%	Explore
uterus	3 studies	41% ± 18%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	3041.48	180 / 180	100%	81.79	430 / 430
brain	100%	8452.87	2638 / 2642	100%	89.97	704 / 705
thymus	100%	3583.83	652 / 653	99%	49.36	598 / 605
uterus	100%	3579.62	170 / 170	98%	63.80	448 / 459
lung	100%	3732.83	577 / 578	97%	53.89	1119 / 1155
esophagus	100%	4960.54	1445 / 1445	96%	43.88	176 / 183
prostate	100%	4821.13	244 / 245	96%	28.40	483 / 502
pancreas	94%	1393.05	308 / 328	96%	65.04	171 / 178
bladder	100%	3889.19	21 / 21	90%	36.05	452 / 504
skin	100%	3759.95	1807 / 1809	89%	43.39	421 / 472
breast	100%	3546.34	459 / 459	89%	49.46	991 / 1118
intestine	100%	3606.69	966 / 966	84%	28.24	444 / 527
stomach	100%	5176.60	359 / 359	84%	40.27	239 / 286
kidney	97%	2207.94	86 / 89	74%	15.95	669 / 901
liver	92%	1180.46	208 / 226	54%	13.13	221 / 406
adrenal gland	93%	1222.67	239 / 258	41%	9.26	95 / 230
adipose	100%	4506.24	1204 / 1204	0%	0	0 / 0
blood vessel	100%	4528.55	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	33.71	29 / 29
spleen	100%	3333.08	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	113.98	45 / 45
ureter	0%	0	0 / 0	100%	36.36	1 / 1
muscle	99%	2186.22	797 / 803	0%	0	0 / 0
heart	95%	2308.00	818 / 861	0%	0	0 / 0
peripheral blood	72%	1342.19	671 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	60%	14.44	48 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0050865	Biological process	regulation of cell activation
GO_0021527	Biological process	spinal cord association neuron differentiation
GO_0031333	Biological process	negative regulation of protein-containing complex assembly
GO_0003281	Biological process	ventricular septum development
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0021520	Biological process	spinal cord motor neuron cell fate specification
GO_0033674	Biological process	positive regulation of kinase activity
GO_0042659	Biological process	regulation of cell fate specification
GO_0030334	Biological process	regulation of cell migration
GO_0048538	Biological process	thymus development
GO_0021514	Biological process	ventral spinal cord interneuron differentiation
GO_0001843	Biological process	neural tube closure
GO_0008045	Biological process	motor neuron axon guidance
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0031252	Cellular component	cell leading edge
GO_0090575	Cellular component	RNA polymerase II transcription regulator complex
GO_0005667	Cellular component	transcription regulator complex
GO_0140297	Molecular function	DNA-binding transcription factor binding
GO_0003714	Molecular function	transcription corepressor activity
GO_0046872	Molecular function	metal ion binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	LMO4
Protein name	LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)
Synonyms
Description	FUNCTION: Transcription cofactor. Plays a role in establishing motor neuron identity, in concert with MNX1, acting, at least in part, to disrupt LDB1-LHX3 complexes thereby negatively modulating interneuron genes in motor neurons. .
Accessions	P61968 ENST00000370542.1 ENST00000370544.10

LMO4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review