LASP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034220Biological processmonoatomic ion transmembrane transport
GO_0006811Biological processmonoatomic ion transport
GO_0030864Cellular componentcortical actin cytoskeleton
GO_0005737Cellular componentcytoplasm
GO_0005925Cellular componentfocal adhesion
GO_0045296Molecular functioncadherin binding
GO_0051015Molecular functionactin filament binding
GO_0015075Molecular functionmonoatomic ion transmembrane transporter activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameLASP1
Protein nameLIM and SH3 domain protein 1
LIM and SH3 protein 1
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
SynonymsMLN50
DescriptionFUNCTION: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). .

FUNCTION: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types. .

FUNCTION: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types. .

AccessionsK7ESD6
ENST00000318008.11 [Q14847-1]
J3KSN1
ENST00000585841.5
F6S2S5
ENST00000433206.6 [Q14847-3]
C9J9W2
ENST00000443937.7
ENST00000579123.1
Q14847
ENST00000419929.1