IMP4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006364Biological processrRNA processing
GO_0030490Biological processmaturation of SSU-rRNA
GO_0042274Biological processribosomal small subunit biogenesis
GO_0005730Cellular componentnucleolus
GO_0034457Cellular componentMpp10 complex
GO_0030684Cellular componentpreribosome
GO_0005654Cellular componentnucleoplasm
GO_0032040Cellular componentsmall-subunit processome
GO_0001650Cellular componentfibrillar center
GO_0042134Molecular functionrRNA primary transcript binding
GO_0030515Molecular functionsnoRNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameIMP4
Protein nameIMP U3 small nucleolar ribonucleoprotein 4
U3 small nucleolar ribonucleoprotein protein IMP4 (U3 snoRNP protein IMP4) (Brix domain-containing protein 4)
SynonymsBXDC4
DescriptionFUNCTION: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing . Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome . .

AccessionsQ96G21
ENST00000452955.1
E7ENR5
B8ZZ47
F8WCN0
H0Y714
ENST00000456713.1
ENST00000259239.8
ENST00000428740.5
ENST00000409649.5
B9A008
ENST00000409935.5