Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 1033.90 | 180 / 180 | 100% | 75.51 | 430 / 430 |
stomach | 100% | 1094.56 | 358 / 359 | 100% | 88.71 | 286 / 286 |
bladder | 100% | 938.95 | 21 / 21 | 100% | 99.15 | 502 / 504 |
intestine | 100% | 883.74 | 962 / 966 | 100% | 96.10 | 525 / 527 |
thymus | 100% | 1140.39 | 651 / 653 | 100% | 67.27 | 602 / 605 |
esophagus | 99% | 871.59 | 1433 / 1445 | 100% | 97.94 | 183 / 183 |
adrenal gland | 100% | 1564.72 | 258 / 258 | 99% | 106.84 | 228 / 230 |
uterus | 99% | 855.26 | 168 / 170 | 100% | 117.57 | 459 / 459 |
breast | 100% | 968.97 | 458 / 459 | 99% | 91.22 | 1107 / 1118 |
lung | 99% | 961.70 | 571 / 578 | 100% | 101.01 | 1153 / 1155 |
kidney | 100% | 1870.39 | 89 / 89 | 98% | 58.42 | 887 / 901 |
prostate | 100% | 889.22 | 244 / 245 | 99% | 55.12 | 496 / 502 |
pancreas | 98% | 950.67 | 323 / 328 | 99% | 70.11 | 176 / 178 |
skin | 97% | 1366.93 | 1755 / 1809 | 98% | 67.98 | 461 / 472 |
liver | 93% | 684.52 | 211 / 226 | 96% | 52.13 | 391 / 406 |
brain | 98% | 2858.14 | 2588 / 2642 | 91% | 41.36 | 643 / 705 |
lymph node | 0% | 0 | 0 / 0 | 100% | 140.32 | 29 / 29 |
spleen | 100% | 1020.68 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 101.18 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 40.57 | 1 / 1 |
adipose | 100% | 953.14 | 1200 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 1034.71 | 1326 / 1335 | 0% | 0 | 0 / 0 |
muscle | 96% | 834.26 | 772 / 803 | 0% | 0 | 0 / 0 |
heart | 93% | 834.54 | 797 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 78% | 1562.55 | 722 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 73% | 24.12 | 58 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006178 | Biological process | guanine salvage |
GO_0007625 | Biological process | grooming behavior |
GO_0044209 | Biological process | AMP salvage |
GO_0048813 | Biological process | dendrite morphogenesis |
GO_0046038 | Biological process | GMP catabolic process |
GO_0001913 | Biological process | T cell mediated cytotoxicity |
GO_0042417 | Biological process | dopamine metabolic process |
GO_0046083 | Biological process | adenine metabolic process |
GO_0032264 | Biological process | IMP salvage |
GO_0021756 | Biological process | striatum development |
GO_0071542 | Biological process | dopaminergic neuron differentiation |
GO_0046651 | Biological process | lymphocyte proliferation |
GO_0043103 | Biological process | hypoxanthine salvage |
GO_0006166 | Biological process | purine ribonucleoside salvage |
GO_0032263 | Biological process | GMP salvage |
GO_0021954 | Biological process | central nervous system neuron development |
GO_0006164 | Biological process | purine nucleotide biosynthetic process |
GO_0001975 | Biological process | response to amphetamine |
GO_0046040 | Biological process | IMP metabolic process |
GO_0046100 | Biological process | hypoxanthine metabolic process |
GO_0045964 | Biological process | positive regulation of dopamine metabolic process |
GO_0021895 | Biological process | cerebral cortex neuron differentiation |
GO_0007626 | Biological process | locomotory behavior |
GO_0051289 | Biological process | protein homotetramerization |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0042802 | Molecular function | identical protein binding |
GO_0000166 | Molecular function | nucleotide binding |
GO_0000287 | Molecular function | magnesium ion binding |
GO_0052657 | Molecular function | guanine phosphoribosyltransferase activity |
GO_0004422 | Molecular function | hypoxanthine phosphoribosyltransferase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | HPRT1 |
Protein name | Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) Hypoxanthine phosphoribosyltransferase (EC 2.4.2.8) Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8) |
Synonyms | HPRT |
Description | FUNCTION: Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway. FUNCTION: Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway. . FUNCTION: Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway. . |
Accessions | ENST00000298556.8 A0A0H3YEQ7 P00492 Q6LET3 A0A140VJL3 |