HIGD1A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
plasmacytoid dendritic cell	17 studies	47% ± 20%	Explore
epithelial cell	15 studies	36% ± 17%	Explore
smooth muscle cell	12 studies	26% ± 5%	Explore
fibroblast	11 studies	28% ± 16%	Explore
natural killer cell	9 studies	18% ± 4%	Explore
basal cell	9 studies	30% ± 13%	Explore
pericyte	8 studies	23% ± 4%	Explore
goblet cell	7 studies	25% ± 13%	Explore
endothelial cell	7 studies	25% ± 8%	Explore
CD8-positive, alpha-beta T cell	7 studies	23% ± 9%	Explore
ciliated cell	7 studies	35% ± 13%	Explore
non-classical monocyte	6 studies	25% ± 9%	Explore
kidney loop of Henle epithelial cell	6 studies	35% ± 9%	Explore
renal alpha-intercalated cell	6 studies	49% ± 18%	Explore
connective tissue cell	6 studies	21% ± 2%	Explore
secretory cell	6 studies	38% ± 11%	Explore
conventional dendritic cell	5 studies	26% ± 10%	Explore
astrocyte	5 studies	30% ± 15%	Explore
CD4-positive, alpha-beta T cell	5 studies	24% ± 10%	Explore
pancreatic A cell	4 studies	71% ± 16%	Explore
epithelial cell of proximal tubule	4 studies	24% ± 3%	Explore
myofibroblast cell	4 studies	23% ± 9%	Explore
retinal ganglion cell	4 studies	64% ± 29%	Explore
erythroblast	4 studies	41% ± 22%	Explore
platelet	4 studies	17% ± 3%	Explore
enterocyte	4 studies	28% ± 8%	Explore
type B pancreatic cell	3 studies	38% ± 9%	Explore
classical monocyte	3 studies	22% ± 2%	Explore
T cell	3 studies	22% ± 2%	Explore
abnormal cell	3 studies	28% ± 17%	Explore
myeloid cell	3 studies	24% ± 8%	Explore
club cell	3 studies	29% ± 7%	Explore
ionocyte	3 studies	31% ± 10%	Explore
amacrine cell	3 studies	34% ± 13%	Explore
retina horizontal cell	3 studies	28% ± 10%	Explore
retinal cone cell	3 studies	66% ± 24%	Explore
retinal rod cell	3 studies	36% ± 17%	Explore
adventitial cell	3 studies	24% ± 7%	Explore
progenitor cell	3 studies	20% ± 2%	Explore
Mueller cell	3 studies	38% ± 11%	Explore
erythrocyte	3 studies	29% ± 15%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	25% ± 9%	Explore
endothelial cell of vascular tree	3 studies	19% ± 3%	Explore
exhausted T cell	3 studies	25% ± 9%	Explore
regulatory T cell	3 studies	25% ± 8%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	41% ± 12%	Explore
luminal cell of prostate epithelium	3 studies	25% ± 7%	Explore
GABAergic neuron	3 studies	35% ± 9%	Explore
glutamatergic neuron	3 studies	49% ± 12%	Explore
pancreatic ductal cell	3 studies	53% ± 18%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	21% ± 4%	Explore
mast cell	3 studies	15% ± 0%	Explore
neuron	3 studies	32% ± 14%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	8 studies	25% ± 10%	Explore
kidney	6 studies	21% ± 5%	Explore
eye	6 studies	30% ± 15%	Explore
peripheral blood	5 studies	18% ± 1%	Explore
brain	5 studies	31% ± 9%	Explore
pancreas	4 studies	47% ± 17%	Explore
intestine	4 studies	24% ± 7%	Explore
liver	3 studies	39% ± 28%	Explore
prostate	3 studies	26% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	9178.90	2642 / 2642	100%	76.91	705 / 705
esophagus	100%	7690.50	1445 / 1445	100%	58.65	183 / 183
bladder	100%	4988.90	21 / 21	100%	56.47	502 / 504
thymus	100%	4743.05	651 / 653	100%	53.10	603 / 605
stomach	100%	4876.32	359 / 359	99%	53.66	284 / 286
breast	100%	4308.44	459 / 459	99%	57.67	1108 / 1118
liver	100%	8506.43	226 / 226	99%	58.40	402 / 406
prostate	100%	5980.33	244 / 245	99%	44.78	499 / 502
uterus	99%	3393.42	168 / 170	100%	49.52	459 / 459
lung	99%	3930.74	572 / 578	100%	41.11	1152 / 1155
adrenal gland	100%	5278.27	258 / 258	99%	67.65	227 / 230
kidney	100%	7243.75	89 / 89	98%	49.18	887 / 901
intestine	100%	6391.91	965 / 966	98%	56.63	519 / 527
skin	99%	4393.86	1794 / 1809	96%	34.65	453 / 472
ovary	94%	2267.68	170 / 180	100%	72.77	430 / 430
pancreas	75%	1284.79	247 / 328	99%	46.07	176 / 178
lymph node	0%	0	0 / 0	100%	32.52	29 / 29
tonsil	0%	0	0 / 0	100%	35.86	45 / 45
ureter	0%	0	0 / 0	100%	48.49	1 / 1
adipose	100%	4892.09	1203 / 1204	0%	0	0 / 0
blood vessel	100%	5957.16	1333 / 1335	0%	0	0 / 0
muscle	100%	5247.68	801 / 803	0%	0	0 / 0
spleen	98%	2209.21	235 / 241	0%	0	0 / 0
heart	95%	7883.37	820 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	71%	14.05	57 / 80
peripheral blood	36%	1328.41	336 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0097250	Biological process	mitochondrial respirasome assembly
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0070469	Cellular component	respirasome
GO_0032991	Cellular component	protein-containing complex
GO_0005654	Cellular component	nucleoplasm
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0005739	Cellular component	mitochondrion

IV. Literature review

[source]

Gene name	HIGD1A
Protein name	HIG1 domain family member 1A, mitochondrial (Hypoxia-inducible gene 1 protein) (RCF1 homolog A) (RCF1a) HIG1 hypoxia inducible domain family member 1A
Synonyms	HSPC010 HIG1
Description	FUNCTION: Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May play a role in the assembly of respiratory supercomplexes. .
Accessions	ENST00000452906.3 [Q9Y241-2] ENST00000418900.6 [Q9Y241-1] Q9Y241 C9JNU6 ENST00000321331.12 [Q9Y241-1] ENST00000430190.5

HIGD1A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review