Name | Number of supported studies | Average coverage | |
---|---|---|---|
erythroblast | 5 studies | 46% ± 17% | |
erythrocyte | 5 studies | 47% ± 22% | |
megakaryocyte | 3 studies | 48% ± 10% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 52% ± 20% | |
hematopoietic stem cell | 3 studies | 20% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
liver | 3 studies | 40% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 144.64 | 577 / 578 | 6% | 0.09 | 72 / 1155 |
spleen | 99% | 131.56 | 238 / 241 | 0% | 0 | 0 / 0 |
bladder | 95% | 31.14 | 20 / 21 | 3% | 0.05 | 16 / 504 |
prostate | 91% | 28.20 | 224 / 245 | 1% | 0.02 | 4 / 502 |
peripheral blood | 83% | 1064.65 | 769 / 929 | 0% | 0 | 0 / 0 |
stomach | 77% | 16.38 | 277 / 359 | 3% | 0.06 | 8 / 286 |
esophagus | 77% | 25.58 | 1109 / 1445 | 2% | 0.02 | 3 / 183 |
adipose | 76% | 19.08 | 910 / 1204 | 0% | 0 | 0 / 0 |
uterus | 74% | 16.01 | 125 / 170 | 2% | 0.07 | 7 / 459 |
intestine | 69% | 17.24 | 662 / 966 | 2% | 0.04 | 11 / 527 |
breast | 64% | 12.19 | 296 / 459 | 6% | 0.10 | 66 / 1118 |
kidney | 49% | 12.39 | 44 / 89 | 5% | 0.14 | 49 / 901 |
skin | 55% | 13.15 | 987 / 1809 | 0% | 0.00 | 1 / 472 |
thymus | 53% | 9.63 | 348 / 653 | 1% | 0.01 | 6 / 605 |
liver | 36% | 7.87 | 81 / 226 | 1% | 0.03 | 4 / 406 |
brain | 31% | 4.82 | 816 / 2642 | 1% | 0.04 | 10 / 705 |
blood vessel | 27% | 4.25 | 354 / 1335 | 0% | 0 | 0 / 0 |
heart | 24% | 3.98 | 208 / 861 | 0% | 0 | 0 / 0 |
adrenal gland | 8% | 1.18 | 21 / 258 | 10% | 4.35 | 24 / 230 |
pancreas | 8% | 0.96 | 25 / 328 | 7% | 0.11 | 12 / 178 |
ovary | 10% | 1.40 | 18 / 180 | 1% | 0.04 | 5 / 430 |
muscle | 6% | 1.17 | 46 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0043306 | Biological process | positive regulation of mast cell degranulation |
GO_0030221 | Biological process | basophil differentiation |
GO_0006366 | Biological process | transcription by RNA polymerase II |
GO_0033687 | Biological process | osteoblast proliferation |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0060319 | Biological process | primitive erythrocyte differentiation |
GO_0048821 | Biological process | erythrocyte development |
GO_0033690 | Biological process | positive regulation of osteoblast proliferation |
GO_0001701 | Biological process | in utero embryonic development |
GO_0060009 | Biological process | Sertoli cell development |
GO_0033028 | Biological process | myeloid cell apoptotic process |
GO_0070527 | Biological process | platelet aggregation |
GO_0071372 | Biological process | cellular response to follicle-stimulating hormone stimulus |
GO_0030222 | Biological process | eosinophil differentiation |
GO_0031100 | Biological process | animal organ regeneration |
GO_0010725 | Biological process | regulation of primitive erythrocyte differentiation |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0097028 | Biological process | dendritic cell differentiation |
GO_0035854 | Biological process | eosinophil fate commitment |
GO_0033033 | Biological process | negative regulation of myeloid cell apoptotic process |
GO_0007267 | Biological process | cell-cell signaling |
GO_0048873 | Biological process | homeostasis of number of cells within a tissue |
GO_0030218 | Biological process | erythrocyte differentiation |
GO_0010724 | Biological process | regulation of definitive erythrocyte differentiation |
GO_0071320 | Biological process | cellular response to cAMP |
GO_2000678 | Biological process | negative regulation of transcription regulatory region DNA binding |
GO_0045165 | Biological process | cell fate commitment |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
GO_0050731 | Biological process | positive regulation of peptidyl-tyrosine phosphorylation |
GO_0030502 | Biological process | negative regulation of bone mineralization |
GO_0030282 | Biological process | bone mineralization |
GO_0045648 | Biological process | positive regulation of erythrocyte differentiation |
GO_0071222 | Biological process | cellular response to lipopolysaccharide |
GO_0008584 | Biological process | male gonad development |
GO_0010559 | Biological process | regulation of glycoprotein biosynthetic process |
GO_2001240 | Biological process | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand |
GO_0030219 | Biological process | megakaryocyte differentiation |
GO_0030220 | Biological process | platelet formation |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0032993 | Cellular component | protein-DNA complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0017053 | Cellular component | transcription repressor complex |
GO_0000785 | Cellular component | chromatin |
GO_0005667 | Cellular component | transcription regulator complex |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0043565 | Molecular function | sequence-specific DNA binding |
GO_0000976 | Molecular function | transcription cis-regulatory region binding |
GO_0001221 | Molecular function | transcription coregulator binding |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0061629 | Molecular function | RNA polymerase II-specific DNA-binding transcription factor binding |
GO_0001223 | Molecular function | transcription coactivator binding |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0008270 | Molecular function | zinc ion binding |
GO_0002039 | Molecular function | p53 binding |
GO_0031490 | Molecular function | chromatin DNA binding |
GO_0005515 | Molecular function | protein binding |
GO_0070742 | Molecular function | C2H2 zinc finger domain binding |
Gene name | GATA1 |
Protein name | Erythroid transcription factor (Eryf1) (GATA-binding factor 1) (GATA-1) (GF-1) (NF-E1 DNA-binding protein) GATA binding protein 1 |
Synonyms | ERYF1 GF1 hCG_19818 |
Description | FUNCTION: Transcriptional activator or repressor which serves as a general switch factor for erythroid development . It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS . . |
Accessions | B7WNQ9 A0A8Q3SIT6 ENST00000696450.1 ENST00000376670.9 [P15976-1] ENST00000376665.4 ENST00000651144.2 [P15976-3] P15976 A0A8Q3SIP6 ENST00000696452.1 A0A8Q3SIN3 ENST00000696451.1 |