Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 22 studies | 38% ± 16% | |
astrocyte | 18 studies | 35% ± 16% | |
oligodendrocyte | 17 studies | 69% ± 21% | |
oligodendrocyte precursor cell | 15 studies | 48% ± 19% | |
microglial cell | 12 studies | 34% ± 12% | |
pericyte | 11 studies | 33% ± 14% | |
fibroblast | 11 studies | 34% ± 14% | |
smooth muscle cell | 10 studies | 32% ± 13% | |
plasma cell | 9 studies | 34% ± 19% | |
macrophage | 7 studies | 37% ± 15% | |
adipocyte | 7 studies | 30% ± 8% | |
epithelial cell | 7 studies | 32% ± 18% | |
glutamatergic neuron | 7 studies | 52% ± 19% | |
type I pneumocyte | 7 studies | 44% ± 20% | |
GABAergic neuron | 6 studies | 30% ± 8% | |
endothelial cell of lymphatic vessel | 6 studies | 43% ± 12% | |
neuron | 5 studies | 29% ± 17% | |
interneuron | 5 studies | 23% ± 5% | |
cardiac muscle cell | 5 studies | 57% ± 16% | |
type II pneumocyte | 5 studies | 36% ± 11% | |
glial cell | 4 studies | 36% ± 13% | |
precursor B cell | 4 studies | 27% ± 1% | |
retinal pigment epithelial cell | 4 studies | 38% ± 17% | |
mesothelial cell | 4 studies | 34% ± 9% | |
Mueller cell | 4 studies | 36% ± 13% | |
B cell | 4 studies | 29% ± 7% | |
club cell | 4 studies | 27% ± 8% | |
goblet cell | 4 studies | 34% ± 16% | |
plasmablast | 3 studies | 34% ± 12% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 57% ± 13% | |
pro-B cell | 3 studies | 41% ± 9% | |
ependymal cell | 3 studies | 43% ± 20% | |
monocyte | 3 studies | 24% ± 4% | |
Schwann cell | 3 studies | 59% ± 25% | |
plasmacytoid dendritic cell | 3 studies | 18% ± 3% | |
dendritic cell | 3 studies | 19% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4759.18 | 1445 / 1445 | 99% | 12.69 | 181 / 183 |
brain | 98% | 2590.01 | 2598 / 2642 | 100% | 32.99 | 702 / 705 |
breast | 100% | 2524.00 | 458 / 459 | 97% | 14.82 | 1089 / 1118 |
intestine | 100% | 3669.95 | 966 / 966 | 94% | 8.08 | 498 / 527 |
stomach | 100% | 2172.70 | 359 / 359 | 94% | 9.37 | 268 / 286 |
lung | 99% | 3247.11 | 574 / 578 | 92% | 8.54 | 1068 / 1155 |
kidney | 99% | 1519.46 | 88 / 89 | 92% | 9.84 | 828 / 901 |
thymus | 100% | 1928.55 | 650 / 653 | 90% | 6.80 | 543 / 605 |
skin | 98% | 2274.15 | 1776 / 1809 | 91% | 11.01 | 428 / 472 |
uterus | 100% | 4072.74 | 170 / 170 | 84% | 6.58 | 387 / 459 |
prostate | 98% | 1800.39 | 240 / 245 | 86% | 6.00 | 433 / 502 |
bladder | 100% | 2198.33 | 21 / 21 | 84% | 6.16 | 423 / 504 |
pancreas | 78% | 732.56 | 257 / 328 | 93% | 7.30 | 165 / 178 |
ovary | 100% | 2781.51 | 180 / 180 | 70% | 3.99 | 299 / 430 |
adrenal gland | 94% | 1813.02 | 243 / 258 | 67% | 3.90 | 155 / 230 |
liver | 75% | 674.81 | 170 / 226 | 43% | 2.50 | 174 / 406 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.31 | 1 / 1 |
blood vessel | 100% | 4546.11 | 1334 / 1335 | 0% | 0 | 0 / 0 |
spleen | 99% | 1412.63 | 239 / 241 | 0% | 0 | 0 / 0 |
adipose | 99% | 2384.67 | 1194 / 1204 | 0% | 0 | 0 / 0 |
heart | 95% | 2550.94 | 821 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 95% | 16.05 | 76 / 80 |
muscle | 91% | 1441.86 | 728 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 82% | 6.22 | 37 / 45 |
lymph node | 0% | 0 | 0 / 0 | 59% | 4.80 | 17 / 29 |
peripheral blood | 40% | 481.16 | 373 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007165 | Biological process | signal transduction |
GO_0007173 | Biological process | epidermal growth factor receptor signaling pathway |
GO_0001525 | Biological process | angiogenesis |
GO_0008286 | Biological process | insulin receptor signaling pathway |
GO_0035728 | Biological process | response to hepatocyte growth factor |
GO_0038084 | Biological process | vascular endothelial growth factor signaling pathway |
GO_0043536 | Biological process | positive regulation of blood vessel endothelial cell migration |
GO_0045766 | Biological process | positive regulation of angiogenesis |
GO_0035767 | Biological process | endothelial cell chemotaxis |
GO_0005911 | Cellular component | cell-cell junction |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0035591 | Molecular function | signaling adaptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | GAB1 |
Protein name | GRB2 associated binding protein 1 GRB2 associated binding protein 1 (cDNA FLJ53999, highly similar to GRB2-associated-binding protein 1) GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1) |
Synonyms | |
Description | FUNCTION: Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway . . |
Accessions | ENST00000512843.1 H0YA71 ENST00000262995.9 [Q13480-2] ENST00000262994.9 [Q13480-1] D6RF42 ENST00000515366.5 ENST00000514639.5 H0Y8F4 D6RIF8 ENST00000505913.5 ENST00000511836.1 D6RIS0 ENST00000509992.1 Q13480 B7Z3B9 |