GAB1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0007173Biological processepidermal growth factor receptor signaling pathway
GO_0001525Biological processangiogenesis
GO_0008286Biological processinsulin receptor signaling pathway
GO_0035728Biological processresponse to hepatocyte growth factor
GO_0038084Biological processvascular endothelial growth factor signaling pathway
GO_0043536Biological processpositive regulation of blood vessel endothelial cell migration
GO_0045766Biological processpositive regulation of angiogenesis
GO_0035767Biological processendothelial cell chemotaxis
GO_0005911Cellular componentcell-cell junction
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0035591Molecular functionsignaling adaptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameGAB1
Protein nameGRB2 associated binding protein 1
GRB2 associated binding protein 1 (cDNA FLJ53999, highly similar to GRB2-associated-binding protein 1)
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
Synonyms
DescriptionFUNCTION: Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway . .

AccessionsENST00000512843.1
H0YA71
ENST00000262995.9 [Q13480-2]
ENST00000262994.9 [Q13480-1]
D6RF42
ENST00000515366.5
ENST00000514639.5
H0Y8F4
D6RIF8
ENST00000505913.5
ENST00000511836.1
D6RIS0
ENST00000509992.1
Q13480
B7Z3B9