F11R | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
ciliated cell	18 studies	35% ± 18%	Explore
type I pneumocyte	11 studies	33% ± 14%	Explore
epithelial cell	10 studies	37% ± 19%	Explore
basal cell	10 studies	30% ± 12%	Explore
endothelial cell	8 studies	20% ± 3%	Explore
secretory cell	8 studies	26% ± 8%	Explore
goblet cell	6 studies	21% ± 5%	Explore
endothelial cell of artery	5 studies	21% ± 6%	Explore
endothelial cell of lymphatic vessel	5 studies	20% ± 5%	Explore
deuterosomal cell	4 studies	25% ± 4%	Explore
squamous epithelial cell	4 studies	44% ± 20%	Explore
type II pneumocyte	3 studies	31% ± 9%	Explore
extravillous trophoblast	3 studies	42% ± 10%	Explore
club cell	3 studies	37% ± 15%	Explore
respiratory goblet cell	3 studies	28% ± 12%	Explore
luminal cell of prostate epithelium	3 studies	45% ± 3%	Explore
megakaryocyte	3 studies	29% ± 14%	Explore
brush cell	3 studies	29% ± 12%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	6 studies	26% ± 12%	Explore
prostate	3 studies	19% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	6001.59	459 / 459	99%	115.50	1110 / 1118
thymus	100%	10376.20	653 / 653	99%	104.41	600 / 605
lung	100%	16345.15	578 / 578	99%	148.90	1142 / 1155
liver	100%	8558.44	226 / 226	98%	90.38	397 / 406
pancreas	100%	5608.91	328 / 328	97%	118.33	173 / 178
prostate	96%	6832.64	236 / 245	99%	56.71	498 / 502
kidney	100%	7318.61	89 / 89	94%	49.40	849 / 901
ovary	97%	3315.99	175 / 180	97%	47.37	417 / 430
stomach	90%	6155.99	322 / 359	97%	66.95	277 / 286
bladder	86%	5377.71	18 / 21	99%	149.21	498 / 504
esophagus	81%	7772.82	1164 / 1445	99%	105.15	181 / 183
intestine	77%	5465.29	740 / 966	98%	86.85	519 / 527
uterus	71%	1745.38	121 / 170	90%	151.45	414 / 459
adrenal gland	100%	5809.55	258 / 258	27%	11.36	61 / 230
skin	72%	7397.84	1306 / 1809	39%	12.85	185 / 472
spleen	100%	5181.40	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	164.04	45 / 45
ureter	0%	0	0 / 0	100%	99.00	1 / 1
adipose	100%	5000.23	1203 / 1204	0%	0	0 / 0
peripheral blood	97%	6070.05	897 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	72%	18.72	21 / 29
heart	68%	1486.68	583 / 861	0%	0	0 / 0
blood vessel	48%	1065.24	637 / 1335	0%	0	0 / 0
brain	20%	406.99	539 / 2642	8%	1.96	56 / 705
eye	0%	0	0 / 0	24%	6.02	19 / 80
muscle	13%	221.86	102 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0072659	Biological process	protein localization to plasma membrane
GO_0006954	Biological process	inflammatory response
GO_0071260	Biological process	cellular response to mechanical stimulus
GO_0035683	Biological process	memory T cell extravasation
GO_1903142	Biological process	positive regulation of establishment of endothelial barrier
GO_0051493	Biological process	regulation of cytoskeleton organization
GO_1902396	Biological process	protein localization to bicellular tight junction
GO_0090559	Biological process	regulation of membrane permeability
GO_0031032	Biological process	actomyosin structure organization
GO_0046718	Biological process	symbiont entry into host cell
GO_2000810	Biological process	regulation of bicellular tight junction assembly
GO_0050892	Biological process	intestinal absorption
GO_0001817	Biological process	regulation of cytokine production
GO_0035633	Biological process	maintenance of blood-brain barrier
GO_1901731	Biological process	positive regulation of platelet aggregation
GO_0090557	Biological process	establishment of endothelial intestinal barrier
GO_0008360	Biological process	regulation of cell shape
GO_0035025	Biological process	positive regulation of Rho protein signal transduction
GO_0098609	Biological process	cell-cell adhesion
GO_0032956	Biological process	regulation of actin cytoskeleton organization
GO_0051497	Biological process	negative regulation of stress fiber assembly
GO_0007159	Biological process	leukocyte cell-cell adhesion
GO_0070160	Cellular component	tight junction
GO_0005886	Cellular component	plasma membrane
GO_0070062	Cellular component	extracellular exosome
GO_0032991	Cellular component	protein-containing complex
GO_0005911	Cellular component	cell-cell junction
GO_0005923	Cellular component	bicellular tight junction
GO_0030054	Cellular component	cell junction
GO_0042803	Molecular function	protein homodimerization activity
GO_0045296	Molecular function	cadherin binding
GO_0001618	Molecular function	virus receptor activity
GO_0005178	Molecular function	integrin binding
GO_0030165	Molecular function	PDZ domain binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	F11R
Protein name	Junctional adhesion molecule A (Junctional adhesion molecule 1) Junctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet F11 receptor) (Platelet adhesion molecule 1) (PAM-1) (CD antigen CD321)
Synonyms	JAM1 JCAM hCG_20857 UNQ264/PRO301
Description	FUNCTION: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 . The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration . Involved in platelet activation . .; FUNCTION: (Microbial infection) Acts as a receptor for Mammalian reovirus sigma-1. .; FUNCTION: (Microbial infection) Acts as a receptor for Human Rotavirus strain Wa. .
Accessions	Q9Y624 Q6FIB4 ENST00000621309.4 A0A087WY82 ENST00000537746.1 [Q9Y624-2] ENST00000368026.11 [Q9Y624-1]

F11R report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review