DYNC1I2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007018Biological processmicrotubule-based movement
GO_0010970Biological processtransport along microtubule
GO_0005813Cellular componentcentrosome
GO_0005829Cellular componentcytosol
GO_0005868Cellular componentcytoplasmic dynein complex
GO_0031982Cellular componentvesicle
GO_0030286Cellular componentdynein complex
GO_0005874Cellular componentmicrotubule
GO_0005737Cellular componentcytoplasm
GO_0045504Molecular functiondynein heavy chain binding
GO_0045503Molecular functiondynein light chain binding
GO_0005515Molecular functionprotein binding
GO_0003777Molecular functionmicrotubule motor activity

IV. Literature review

[source]
Gene nameDYNC1I2
Protein nameDynein cytoplasmic 1 intermediate chain 2
Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)
SynonymsDNCI2
DNCIC2
DescriptionFUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function . Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules . The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1 (By similarity). Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes (By similarity). .

AccessionsE7ERH4
ENST00000412370.5
ENST00000422646.1
ENST00000709741.1 [Q13409-5]
Q13409
E7EU01
ENST00000709732.1 [Q13409-7]
ENST00000452242.5
E7ESD3
ENST00000435234.5
ENST00000438879.5
ENST00000423910.5
ENST00000709731.1 [Q13409-1]
ENST00000709735.1 [Q13409-6]
ENST00000709730.1 [Q13409-3]
ENST00000445378.5
ENST00000397119.8 [Q13409-1]
ENST00000409197.5 [Q13409-3]
E7EV09
ENST00000508530.5 [Q13409-6]
ENST00000340296.8 [Q13409-3]
E7ERR6
ENST00000409773.5 [Q13409-1]
E7EUM4
ENST00000411953.5
ENST00000430778.5
ENST00000410079.7 [Q13409-7]
ENST00000709738.1 [Q13409-2]
E7EQL5
ENST00000409317.5 [Q13409-2]
ENST00000409453.5 [Q13409-5]
ENST00000456808.5
ENST00000709736.1 [Q13409-3]
E7EMU4
ENST00000443458.5
E7ETL8
ENST00000425485.5
ENST00000709739.1 [Q13409-1]
E9PGG1
E7EQU2
E7ET01