DPF2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0097190Biological processapoptotic signaling pathway
GO_0030071Biological processregulation of mitotic metaphase/anaphase transition
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_2000045Biological processregulation of G1/S transition of mitotic cell cycle
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006338Biological processchromatin remodeling
GO_0070316Biological processregulation of G0 to G1 transition
GO_1902459Biological processpositive regulation of stem cell population maintenance
GO_2000819Biological processregulation of nucleotide-excision repair
GO_0006915Biological processapoptotic process
GO_1905454Biological processnegative regulation of myeloid progenitor cell differentiation
GO_2000781Biological processpositive regulation of double-strand break repair
GO_0007399Biological processnervous system development
GO_0071565Cellular componentnBAF complex
GO_0005813Cellular componentcentrosome
GO_0016514Cellular componentSWI/SNF complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0062072Molecular functionH3K9me3 modified histone binding
GO_0070577Molecular functionlysine-acetylated histone binding
GO_0003714Molecular functiontranscription corepressor activity
GO_0046872Molecular functionmetal ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDPF2
Protein nameZinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (BRG1-associated factor 45D) (BAF45D) (D4, zinc and double PHD fingers family 2) (Protein requiem)
Double PHD fingers 2
SynonymsREQ
UBID4
BAF45D
DescriptionFUNCTION: Plays an active role in transcriptional regulation by binding modified histones H3 and H4 . Is a negative regulator of myeloid differentiation of hematopoietic progenitor cells . Might also have a role in the development and maturation of lymphoid cells (By similarity). Involved in the regulation of non-canonical NF-kappa-B pathway . .

AccessionsENST00000703426.1
ENST00000703393.1
A0A994J3H5
ENST00000530993.6
A0A994J3P2
ENST00000531989.1
Q92785
ENST00000528416.6 [Q92785-1]
A0A994J6N1
ENST00000703425.1
ENST00000415073.6 [Q92785-2]
A0A994J6A8
E9PN04
ENST00000532102.5
A0A994J414
H0YEI1
ENST00000703424.1
J3KMZ8
ENST00000703427.1
ENST00000252268.8
A0A994J426