DNAJC21 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	10 studies	24% ± 5%	Explore
B cell	6 studies	24% ± 6%	Explore
natural killer cell	6 studies	22% ± 4%	Explore
epithelial cell	6 studies	37% ± 18%	Explore
basal cell	6 studies	27% ± 12%	Explore
smooth muscle cell	5 studies	20% ± 2%	Explore
mast cell	4 studies	22% ± 2%	Explore
endothelial cell of lymphatic vessel	4 studies	22% ± 5%	Explore
fibroblast	4 studies	21% ± 3%	Explore
ciliated cell	4 studies	31% ± 13%	Explore
astrocyte	4 studies	22% ± 4%	Explore
endothelial cell of vascular tree	4 studies	19% ± 3%	Explore
oligodendrocyte	4 studies	22% ± 2%	Explore
classical monocyte	3 studies	31% ± 7%	Explore
leukocyte	3 studies	22% ± 3%	Explore
naive B cell	3 studies	21% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	24% ± 2%	Explore
non-classical monocyte	3 studies	29% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	23% ± 5%	Explore
CD8-positive, alpha-beta T cell	3 studies	24% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	26% ± 3%	Explore
hematopoietic precursor cell	3 studies	28% ± 15%	Explore
mature NK T cell	3 studies	21% ± 1%	Explore
myeloid cell	3 studies	25% ± 8%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	23% ± 5%	Explore
gamma-delta T cell	3 studies	29% ± 6%	Explore
pericyte	3 studies	19% ± 2%	Explore
regulatory T cell	3 studies	18% ± 3%	Explore
GABAergic neuron	3 studies	41% ± 5%	Explore
glutamatergic neuron	3 studies	51% ± 8%	Explore
goblet cell	3 studies	19% ± 1%	Explore
intestinal crypt stem cell	3 studies	18% ± 1%	Explore
transit amplifying cell	3 studies	22% ± 5%	Explore
plasmacytoid dendritic cell	3 studies	19% ± 1%	Explore
interneuron	3 studies	32% ± 21%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	4 studies	29% ± 12%	Explore
peripheral blood	4 studies	30% ± 6%	Explore
brain	4 studies	36% ± 7%	Explore
intestine	3 studies	20% ± 2%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3420.24	1445 / 1445	100%	22.78	183 / 183
ovary	100%	2211.41	180 / 180	100%	14.23	430 / 430
uterus	100%	3123.72	170 / 170	100%	26.80	459 / 459
lung	100%	2723.58	578 / 578	100%	27.39	1154 / 1155
breast	100%	2399.94	459 / 459	100%	26.47	1117 / 1118
prostate	100%	2648.65	245 / 245	100%	21.69	501 / 502
bladder	100%	3272.19	21 / 21	99%	22.42	501 / 504
stomach	100%	2179.30	359 / 359	99%	17.99	284 / 286
liver	100%	1494.49	226 / 226	99%	13.89	403 / 406
intestine	100%	2970.13	966 / 966	99%	17.95	523 / 527
brain	100%	1849.95	2632 / 2642	100%	9.88	702 / 705
thymus	100%	2481.24	653 / 653	99%	22.15	600 / 605
pancreas	100%	1582.50	327 / 328	99%	17.70	177 / 178
kidney	100%	2169.64	89 / 89	99%	15.69	888 / 901
adrenal gland	100%	2024.88	258 / 258	96%	12.39	221 / 230
skin	100%	2824.00	1808 / 1809	93%	17.73	438 / 472
adipose	100%	2565.32	1204 / 1204	0%	0	0 / 0
blood vessel	100%	3452.37	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	17.48	29 / 29
muscle	100%	5345.35	803 / 803	0%	0	0 / 0
spleen	100%	1614.15	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	25.16	45 / 45
ureter	0%	0	0 / 0	100%	6.25	1 / 1
heart	96%	2685.23	829 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	60%	6.91	48 / 80
peripheral blood	49%	1214.97	456 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0