DENND1C report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	12 studies	19% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	23% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	19% ± 5%	Explore
regulatory T cell	9 studies	19% ± 2%	Explore
gamma-delta T cell	9 studies	20% ± 4%	Explore
CD4-positive, alpha-beta T cell	8 studies	20% ± 5%	Explore
CD8-positive, alpha-beta T cell	8 studies	22% ± 6%	Explore
mature NK T cell	6 studies	17% ± 1%	Explore
mucosal invariant T cell	6 studies	18% ± 1%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	22% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	24% ± 6%	Explore
T cell	5 studies	16% ± 1%	Explore
T follicular helper cell	4 studies	18% ± 1%	Explore
memory B cell	4 studies	18% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	19% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	20% ± 2%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	23% ± 3%	Explore
classical monocyte	3 studies	18% ± 1%	Explore
non-classical monocyte	3 studies	19% ± 4%	Explore
dendritic cell	3 studies	21% ± 4%	Explore
double negative thymocyte	3 studies	19% ± 3%	Explore

II. Expression across tissues

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	985.42	89 / 89	98%	32.55	887 / 901
thymus	99%	732.34	649 / 653	98%	22.63	593 / 605
lung	100%	1777.71	578 / 578	97%	16.76	1123 / 1155
pancreas	98%	505.06	323 / 328	98%	19.09	175 / 178
prostate	95%	576.31	232 / 245	98%	18.83	491 / 502
liver	100%	524.25	226 / 226	87%	11.97	353 / 406
stomach	86%	741.12	308 / 359	98%	17.40	279 / 286
breast	76%	308.51	349 / 459	97%	14.69	1079 / 1118
intestine	67%	1377.05	652 / 966	99%	19.51	523 / 527
bladder	67%	444.29	14 / 21	91%	12.52	459 / 504
esophagus	58%	381.59	842 / 1445	93%	11.42	171 / 183
skin	72%	612.20	1304 / 1809	62%	8.79	291 / 472
uterus	43%	131.59	73 / 170	86%	12.07	397 / 459
ovary	14%	41.62	26 / 180	93%	10.43	398 / 430
adrenal gland	91%	341.30	235 / 258	13%	1.30	30 / 230
lymph node	0%	0	0 / 0	100%	74.27	29 / 29
peripheral blood	100%	6974.71	929 / 929	0%	0	0 / 0
spleen	100%	7854.54	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	96%	19.16	43 / 45
brain	54%	216.01	1437 / 2642	37%	2.56	263 / 705
eye	0%	0	0 / 0	88%	8.80	70 / 80
adipose	87%	420.79	1053 / 1204	0%	0	0 / 0
blood vessel	37%	179.80	499 / 1335	0%	0	0 / 0
heart	15%	46.85	126 / 861	0%	0	0 / 0
muscle	1%	1.56	5 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1