CXCL2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0071222Biological processcellular response to lipopolysaccharide
GO_0002237Biological processresponse to molecule of bacterial origin
GO_0061844Biological processantimicrobial humoral immune response mediated by antimicrobial peptide
GO_0030593Biological processneutrophil chemotaxis
GO_0070098Biological processchemokine-mediated signaling pathway
GO_0006954Biological processinflammatory response
GO_0006935Biological processchemotaxis
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0045236Molecular functionCXCR chemokine receptor binding
GO_0005515Molecular functionprotein binding
GO_0008009Molecular functionchemokine activity

IV. Literature review

[source]
Gene nameCXCL2
Protein nameC-X-C motif chemokine 2 (Growth-regulated protein beta) (Gro-beta) (Macrophage inflammatory protein 2-alpha) (MIP2-alpha) [Cleaved into: GRO-beta(5-73) (GRO-beta-T) (Hematopoietic synergistic factor) (HSF) (SB-251353)]
SynonymsGRO2
SCYB2
MIP2A
GROB
DescriptionFUNCTION: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. .

AccessionsENST00000508487.3
P19875