Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 26 studies | 40% ± 20% | |
| endothelial cell | 20 studies | 32% ± 11% | |
| fibroblast | 17 studies | 29% ± 15% | |
| classical monocyte | 14 studies | 45% ± 25% | |
| monocyte | 13 studies | 38% ± 15% | |
| endothelial cell of lymphatic vessel | 11 studies | 33% ± 16% | |
| basal cell | 11 studies | 36% ± 22% | |
| endothelial cell of artery | 11 studies | 38% ± 14% | |
| type II pneumocyte | 10 studies | 45% ± 22% | |
| endothelial cell of vascular tree | 10 studies | 37% ± 13% | |
| smooth muscle cell | 9 studies | 20% ± 4% | |
| non-classical monocyte | 8 studies | 40% ± 17% | |
| pericyte | 8 studies | 32% ± 8% | |
| epithelial cell | 8 studies | 28% ± 17% | |
| conventional dendritic cell | 8 studies | 31% ± 13% | |
| vein endothelial cell | 8 studies | 35% ± 13% | |
| secretory cell | 7 studies | 46% ± 21% | |
| dendritic cell | 6 studies | 29% ± 15% | |
| myeloid cell | 6 studies | 43% ± 14% | |
| capillary endothelial cell | 6 studies | 29% ± 13% | |
| alveolar macrophage | 5 studies | 28% ± 7% | |
| type I pneumocyte | 5 studies | 30% ± 12% | |
| mononuclear phagocyte | 5 studies | 40% ± 16% | |
| neutrophil | 5 studies | 35% ± 15% | |
| club cell | 4 studies | 42% ± 18% | |
| ciliated cell | 4 studies | 38% ± 18% | |
| inflammatory macrophage | 4 studies | 36% ± 15% | |
| luminal hormone-sensing cell of mammary gland | 4 studies | 32% ± 10% | |
| hepatocyte | 4 studies | 49% ± 21% | |
| leukocyte | 4 studies | 26% ± 11% | |
| connective tissue cell | 4 studies | 26% ± 8% | |
| T cell | 3 studies | 24% ± 8% | |
| pancreatic ductal cell | 3 studies | 49% ± 13% | |
| progenitor cell of mammary luminal epithelium | 3 studies | 57% ± 22% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 14779.63 | 226 / 226 | 87% | 72.28 | 352 / 406 |
| lung | 99% | 5122.24 | 575 / 578 | 83% | 63.85 | 956 / 1155 |
| stomach | 76% | 1250.40 | 273 / 359 | 91% | 72.01 | 260 / 286 |
| intestine | 67% | 531.04 | 643 / 966 | 91% | 63.07 | 482 / 527 |
| pancreas | 83% | 3302.43 | 271 / 328 | 75% | 30.83 | 133 / 178 |
| esophagus | 62% | 543.46 | 889 / 1445 | 70% | 53.52 | 129 / 183 |
| kidney | 78% | 792.92 | 69 / 89 | 52% | 21.27 | 465 / 901 |
| thymus | 52% | 361.04 | 341 / 653 | 58% | 38.18 | 351 / 605 |
| breast | 91% | 1237.23 | 416 / 459 | 17% | 4.66 | 192 / 1118 |
| prostate | 55% | 713.19 | 135 / 245 | 39% | 21.19 | 194 / 502 |
| heart | 91% | 1736.00 | 783 / 861 | 0% | 0 | 0 / 0 |
| adipose | 90% | 2871.14 | 1081 / 1204 | 0% | 0 | 0 / 0 |
| bladder | 29% | 250.90 | 6 / 21 | 54% | 30.49 | 272 / 504 |
| muscle | 81% | 706.49 | 653 / 803 | 0% | 0 | 0 / 0 |
| ovary | 37% | 425.62 | 67 / 180 | 41% | 13.96 | 178 / 430 |
| brain | 26% | 134.22 | 684 / 2642 | 49% | 12.57 | 344 / 705 |
| uterus | 25% | 162.02 | 43 / 170 | 46% | 30.52 | 211 / 459 |
| adrenal gland | 47% | 503.21 | 122 / 258 | 23% | 12.54 | 54 / 230 |
| spleen | 62% | 407.34 | 150 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 61% | 727.38 | 815 / 1335 | 0% | 0 | 0 / 0 |
| skin | 40% | 318.00 | 722 / 1809 | 8% | 2.60 | 39 / 472 |
| tonsil | 0% | 0 | 0 / 0 | 24% | 7.11 | 11 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 14% | 3.05 | 4 / 29 |
| peripheral blood | 5% | 44.73 | 48 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0071222 | Biological process | cellular response to lipopolysaccharide |
| GO_0002237 | Biological process | response to molecule of bacterial origin |
| GO_0061844 | Biological process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| GO_0030593 | Biological process | neutrophil chemotaxis |
| GO_0070098 | Biological process | chemokine-mediated signaling pathway |
| GO_0006954 | Biological process | inflammatory response |
| GO_0006935 | Biological process | chemotaxis |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0045236 | Molecular function | CXCR chemokine receptor binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0008009 | Molecular function | chemokine activity |
| Gene name | CXCL2 |
| Protein name | C-X-C motif chemokine 2 (Growth-regulated protein beta) (Gro-beta) (Macrophage inflammatory protein 2-alpha) (MIP2-alpha) [Cleaved into: GRO-beta(5-73) (GRO-beta-T) (Hematopoietic synergistic factor) (HSF) (SB-251353)] |
| Synonyms | GRO2 SCYB2 MIP2A GROB |
| Description | FUNCTION: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. . |
| Accessions | ENST00000508487.3 P19875 |