CCPG1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	25 studies	24% ± 8%	Explore
fibroblast	22 studies	23% ± 8%	Explore
plasma cell	18 studies	34% ± 11%	Explore
ciliated cell	14 studies	32% ± 12%	Explore
macrophage	11 studies	20% ± 4%	Explore
natural killer cell	10 studies	18% ± 4%	Explore
endothelial cell of lymphatic vessel	10 studies	21% ± 4%	Explore
classical monocyte	10 studies	26% ± 9%	Explore
non-classical monocyte	10 studies	26% ± 10%	Explore
smooth muscle cell	9 studies	19% ± 2%	Explore
alveolar macrophage	8 studies	25% ± 6%	Explore
epithelial cell	8 studies	31% ± 14%	Explore
basal cell	7 studies	29% ± 15%	Explore
astrocyte	7 studies	23% ± 7%	Explore
type I pneumocyte	6 studies	24% ± 4%	Explore
club cell	6 studies	27% ± 5%	Explore
respiratory goblet cell	6 studies	37% ± 11%	Explore
GABAergic neuron	6 studies	39% ± 17%	Explore
capillary endothelial cell	6 studies	23% ± 5%	Explore
endothelial cell of artery	6 studies	21% ± 3%	Explore
IgG plasma cell	6 studies	20% ± 5%	Explore
glutamatergic neuron	6 studies	57% ± 16%	Explore
platelet	6 studies	24% ± 4%	Explore
adipocyte	6 studies	21% ± 5%	Explore
IgA plasma cell	6 studies	26% ± 7%	Explore
monocyte	6 studies	25% ± 11%	Explore
secretory cell	5 studies	42% ± 12%	Explore
connective tissue cell	5 studies	20% ± 5%	Explore
pericyte	5 studies	25% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	18% ± 2%	Explore
type II pneumocyte	4 studies	21% ± 8%	Explore
deuterosomal cell	4 studies	26% ± 10%	Explore
duct epithelial cell	4 studies	29% ± 12%	Explore
plasmablast	4 studies	37% ± 19%	Explore
myeloid cell	4 studies	30% ± 10%	Explore
cardiac muscle cell	4 studies	20% ± 2%	Explore
vein endothelial cell	4 studies	17% ± 1%	Explore
retinal rod cell	4 studies	27% ± 6%	Explore
oligodendrocyte	4 studies	22% ± 6%	Explore
neutrophil	4 studies	33% ± 14%	Explore
goblet cell	4 studies	22% ± 4%	Explore
oligodendrocyte precursor cell	4 studies	19% ± 1%	Explore
ionocyte	3 studies	37% ± 10%	Explore
squamous epithelial cell	3 studies	45% ± 25%	Explore
type B pancreatic cell	3 studies	25% ± 5%	Explore
conventional dendritic cell	3 studies	24% ± 1%	Explore
mature NK T cell	3 studies	17% ± 0%	Explore
glomerular endothelial cell	3 studies	32% ± 4%	Explore
neuron	3 studies	23% ± 1%	Explore
kidney loop of Henle epithelial cell	3 studies	23% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	19% ± 2%	Explore
adventitial cell	3 studies	22% ± 1%	Explore
mucus secreting cell	3 studies	26% ± 0%	Explore
serous secreting cell	3 studies	24% ± 3%	Explore
amacrine cell	3 studies	21% ± 6%	Explore
retina horizontal cell	3 studies	25% ± 8%	Explore
retinal cone cell	3 studies	24% ± 7%	Explore
endothelial cell of vascular tree	3 studies	24% ± 9%	Explore
myofibroblast cell	3 studies	21% ± 6%	Explore
megakaryocyte	3 studies	32% ± 9%	Explore
interneuron	3 studies	66% ± 14%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	9 studies	26% ± 13%	Explore
brain	8 studies	36% ± 18%	Explore
peripheral blood	4 studies	21% ± 5%	Explore
eye	4 studies	22% ± 4%	Explore
kidney	4 studies	18% ± 3%	Explore
pancreas	3 studies	24% ± 6%	Explore
intestine	3 studies	17% ± 1%	Explore
adipose	3 studies	20% ± 2%	Explore
liver	3 studies	16% ± 0%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	3633.02	244 / 245	100%	9.18	501 / 502
kidney	100%	3423.94	89 / 89	99%	8.49	895 / 901
breast	100%	4802.47	459 / 459	99%	7.56	1106 / 1118
brain	100%	5128.62	2635 / 2642	99%	5.00	696 / 705
thymus	100%	5936.16	653 / 653	98%	9.30	590 / 605
adrenal gland	100%	4741.41	258 / 258	97%	9.87	224 / 230
pancreas	100%	5930.45	328 / 328	97%	7.46	173 / 178
liver	100%	3607.15	226 / 226	97%	5.60	392 / 406
lung	100%	4559.55	577 / 578	96%	6.87	1114 / 1155
stomach	100%	5011.89	359 / 359	93%	5.03	267 / 286
esophagus	95%	3163.27	1379 / 1445	95%	5.63	174 / 183
uterus	99%	3870.65	169 / 170	88%	4.13	402 / 459
intestine	100%	3808.39	966 / 966	85%	4.36	449 / 527
ovary	100%	3061.93	180 / 180	85%	3.22	365 / 430
skin	98%	2953.36	1778 / 1809	84%	5.14	395 / 472
bladder	100%	3407.81	21 / 21	76%	3.27	381 / 504
blood vessel	100%	8423.77	1335 / 1335	0%	0	0 / 0
spleen	100%	3399.36	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	3.02	1 / 1
adipose	100%	5177.06	1203 / 1204	0%	0	0 / 0
muscle	100%	5103.76	802 / 803	0%	0	0 / 0
heart	96%	4099.35	830 / 861	0%	0	0 / 0
peripheral blood	96%	6952.36	890 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	84%	3.25	38 / 45
lymph node	0%	0	0 / 0	83%	3.07	24 / 29
eye	0%	0	0 / 0	38%	1.46	30 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_2001106	Biological process	regulation of Rho guanyl-nucleotide exchange factor activity
GO_0045787	Biological process	positive regulation of cell cycle
GO_0016020	Cellular component	membrane
GO_0005515	Molecular function	protein binding
GO_0003674	Molecular function	molecular_function

IV. Literature review

[source]

Gene name	CCPG1
Protein name	Cell cycle progression protein 1 (Cell cycle progression restoration protein 8) Cell cycle progression 1
Synonyms	CPR8 KIAA1254 CCP8
Description	FUNCTION: Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity). May be involved in cell cycle regulation. .
Accessions	ENST00000442196.8 [Q9ULG6-5] ENST00000310958.10 [Q9ULG6-1] ENST00000563171.5 H3BQN1 ENST00000568543.1 H3BN32 ENST00000568592.1 ENST00000570272.5 ENST00000564663.1 ENST00000425574.7 [Q9ULG6-3] H3BNE2 ENST00000568808.5 H3BV63 H3BR24 H3BTZ1 Q9ULG6 H3BPP4 ENST00000569205.5 [Q9ULG6-1] ENST00000564092.1

CCPG1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review