CCNL2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	28 studies	26% ± 9%	Explore
fibroblast	20 studies	23% ± 5%	Explore
pericyte	15 studies	23% ± 7%	Explore
smooth muscle cell	12 studies	20% ± 3%	Explore
capillary endothelial cell	10 studies	17% ± 2%	Explore
adipocyte	10 studies	33% ± 9%	Explore
astrocyte	10 studies	31% ± 12%	Explore
basal cell	9 studies	30% ± 13%	Explore
ciliated cell	9 studies	30% ± 9%	Explore
endothelial cell of lymphatic vessel	8 studies	23% ± 7%	Explore
type I pneumocyte	8 studies	23% ± 5%	Explore
macrophage	8 studies	21% ± 5%	Explore
natural killer cell	7 studies	19% ± 4%	Explore
epithelial cell	7 studies	36% ± 18%	Explore
type II pneumocyte	7 studies	22% ± 6%	Explore
vein endothelial cell	7 studies	21% ± 9%	Explore
glutamatergic neuron	6 studies	38% ± 20%	Explore
myofibroblast cell	6 studies	25% ± 7%	Explore
oligodendrocyte	6 studies	26% ± 5%	Explore
goblet cell	6 studies	25% ± 12%	Explore
B cell	5 studies	21% ± 2%	Explore
T cell	5 studies	23% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	19% ± 2%	Explore
endothelial cell of vascular tree	5 studies	21% ± 7%	Explore
endothelial cell of artery	5 studies	17% ± 1%	Explore
regulatory T cell	5 studies	22% ± 7%	Explore
CD8-positive, alpha-beta T cell	5 studies	19% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	17% ± 2%	Explore
GABAergic neuron	5 studies	36% ± 12%	Explore
oligodendrocyte precursor cell	5 studies	28% ± 7%	Explore
club cell	5 studies	22% ± 7%	Explore
naive B cell	5 studies	18% ± 1%	Explore
secretory cell	4 studies	28% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	17% ± 1%	Explore
neuron	4 studies	31% ± 10%	Explore
microglial cell	4 studies	23% ± 2%	Explore
myeloid cell	4 studies	21% ± 4%	Explore
lymphocyte	4 studies	21% ± 4%	Explore
abnormal cell	4 studies	32% ± 12%	Explore
interneuron	4 studies	35% ± 19%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	22% ± 2%	Explore
ionocyte	3 studies	24% ± 6%	Explore
CD4-positive, alpha-beta T cell	3 studies	20% ± 1%	Explore
classical monocyte	3 studies	23% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	20% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	17% ± 2%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	21% ± 4%	Explore
glomerular endothelial cell	3 studies	25% ± 1%	Explore
connective tissue cell	3 studies	23% ± 8%	Explore
progenitor cell	3 studies	21% ± 5%	Explore
squamous epithelial cell	3 studies	36% ± 20%	Explore
respiratory goblet cell	3 studies	27% ± 5%	Explore
hepatocyte	3 studies	41% ± 15%	Explore
muscle cell	3 studies	25% ± 12%	Explore
monocyte	3 studies	20% ± 3%	Explore
transit amplifying cell	3 studies	30% ± 18%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	10 studies	30% ± 14%	Explore
lung	7 studies	25% ± 7%	Explore
intestine	4 studies	22% ± 8%	Explore
adipose	4 studies	30% ± 18%	Explore
peripheral blood	3 studies	23% ± 4%	Explore
liver	3 studies	31% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	22226.67	21 / 21	100%	73.41	502 / 504
prostate	100%	28119.50	245 / 245	100%	54.93	500 / 502
uterus	100%	28587.24	170 / 170	100%	76.86	457 / 459
esophagus	100%	18940.94	1445 / 1445	99%	48.82	182 / 183
thymus	100%	28388.68	653 / 653	99%	64.45	601 / 605
breast	100%	21467.50	459 / 459	99%	46.51	1107 / 1118
intestine	100%	20747.75	966 / 966	98%	43.28	517 / 527
adrenal gland	100%	21249.70	258 / 258	98%	37.99	225 / 230
pancreas	100%	12799.67	328 / 328	98%	64.87	174 / 178
lung	100%	19178.09	578 / 578	98%	55.69	1127 / 1155
ovary	100%	29209.45	180 / 180	95%	43.51	408 / 430
stomach	100%	15157.64	359 / 359	95%	37.76	271 / 286
skin	100%	16996.15	1809 / 1809	94%	50.41	445 / 472
brain	94%	10659.92	2494 / 2642	100%	61.78	702 / 705
liver	100%	17117.22	226 / 226	93%	34.53	379 / 406
kidney	100%	19056.00	89 / 89	85%	44.67	769 / 901
adipose	100%	18683.16	1204 / 1204	0%	0	0 / 0
spleen	100%	23120.49	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	65.83	1 / 1
blood vessel	100%	15145.08	1334 / 1335	0%	0	0 / 0
heart	99%	9248.99	856 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	44.89	28 / 29
muscle	97%	6636.61	775 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	91%	42.21	41 / 45
peripheral blood	76%	4580.39	709 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	71%	25.53	57 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0043484	Biological process	regulation of RNA splicing
GO_0042981	Biological process	regulation of apoptotic process
GO_0051726	Biological process	regulation of cell cycle
GO_0046605	Biological process	regulation of centrosome cycle
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0016607	Cellular component	nuclear speck
GO_0000307	Cellular component	cyclin-dependent protein kinase holoenzyme complex
GO_0005654	Cellular component	nucleoplasm
GO_0005634	Cellular component	nucleus
GO_0016538	Molecular function	cyclin-dependent protein serine/threonine kinase regulator activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	CCNL2
Protein name	Cyclin L2 Cyclin-L2 (Paneth cell-enhanced expression protein)
Synonyms	SB138
Description	FUNCTION: Involved in pre-mRNA splicing. May induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors. .
Accessions	ENST00000482621.5 ENST00000400809.8 [Q96S94-1] ENST00000425598.2 ENST00000481223.6 [Q96S94-4] ENST00000408918.8 [Q96S94-5] ENST00000488340.5 [Q96S94-2] J3KRL1 J3QSH2 ENST00000497013.1 Q96S94 C9J148

CCNL2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review