BZW2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
epithelial cell	8 studies	37% ± 13%	Explore
endothelial cell	8 studies	25% ± 11%	Explore
myofibroblast cell	7 studies	27% ± 9%	Explore
fibroblast	7 studies	20% ± 4%	Explore
glutamatergic neuron	7 studies	37% ± 18%	Explore
CD4-positive, alpha-beta T cell	6 studies	29% ± 8%	Explore
interneuron	6 studies	28% ± 12%	Explore
hematopoietic stem cell	6 studies	35% ± 8%	Explore
basal cell	6 studies	32% ± 13%	Explore
CD8-positive, alpha-beta T cell	6 studies	27% ± 8%	Explore
retinal rod cell	6 studies	31% ± 8%	Explore
conventional dendritic cell	5 studies	35% ± 14%	Explore
connective tissue cell	5 studies	23% ± 4%	Explore
pericyte	5 studies	23% ± 4%	Explore
smooth muscle cell	5 studies	27% ± 6%	Explore
endothelial cell of lymphatic vessel	5 studies	21% ± 4%	Explore
retinal cone cell	5 studies	42% ± 10%	Explore
cardiac muscle cell	5 studies	38% ± 4%	Explore
neuron	5 studies	29% ± 11%	Explore
GABAergic neuron	5 studies	33% ± 7%	Explore
hematopoietic precursor cell	4 studies	47% ± 12%	Explore
progenitor cell	4 studies	21% ± 4%	Explore
vein endothelial cell	4 studies	28% ± 14%	Explore
erythroblast	4 studies	33% ± 15%	Explore
type II pneumocyte	4 studies	20% ± 5%	Explore
abnormal cell	4 studies	21% ± 4%	Explore
oligodendrocyte precursor cell	4 studies	29% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	23% ± 6%	Explore
non-classical monocyte	3 studies	17% ± 2%	Explore
extravillous trophoblast	3 studies	85% ± 9%	Explore
placental villous trophoblast	3 studies	71% ± 16%	Explore
common myeloid progenitor	3 studies	35% ± 21%	Explore
brush cell	3 studies	31% ± 10%	Explore
precursor B cell	3 studies	20% ± 4%	Explore
pro-B cell	3 studies	28% ± 10%	Explore
ciliated cell	3 studies	27% ± 2%	Explore
dendritic cell	3 studies	42% ± 10%	Explore
granulocyte monocyte progenitor cell	3 studies	26% ± 4%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	48% ± 24%	Explore
intestinal crypt stem cell	3 studies	27% ± 4%	Explore
transit amplifying cell	3 studies	33% ± 13%	Explore
plasmacytoid dendritic cell	3 studies	23% ± 3%	Explore
natural killer cell	3 studies	23% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	7 studies	30% ± 13%	Explore
eye	6 studies	25% ± 6%	Explore
intestine	5 studies	22% ± 8%	Explore
placenta	4 studies	42% ± 20%	Explore
heart	4 studies	18% ± 2%	Explore
lung	3 studies	24% ± 6%	Explore
bone marrow	3 studies	19% ± 2%	Explore
liver	3 studies	27% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2956.66	1445 / 1445	100%	81.38	183 / 183
breast	100%	2695.05	459 / 459	100%	92.26	1117 / 1118
intestine	100%	2584.37	966 / 966	100%	100.65	526 / 527
bladder	100%	3409.14	21 / 21	100%	91.81	503 / 504
stomach	100%	2993.99	358 / 359	100%	89.04	286 / 286
skin	100%	4147.27	1809 / 1809	99%	105.22	466 / 472
lung	98%	1914.16	569 / 578	100%	77.79	1155 / 1155
uterus	99%	1467.72	168 / 170	100%	66.62	457 / 459
thymus	100%	3041.91	652 / 653	99%	41.74	596 / 605
prostate	98%	1598.42	241 / 245	98%	39.90	493 / 502
ovary	96%	1290.21	173 / 180	99%	53.81	427 / 430
pancreas	98%	1566.00	321 / 328	97%	45.44	172 / 178
kidney	96%	1401.52	85 / 89	81%	22.51	726 / 901
adrenal gland	100%	1574.26	258 / 258	66%	16.20	151 / 230
brain	65%	748.51	1705 / 2642	95%	36.70	670 / 705
liver	50%	517.76	114 / 226	65%	18.02	262 / 406
lymph node	0%	0	0 / 0	100%	64.99	29 / 29
muscle	100%	8461.79	803 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	52.40	45 / 45
ureter	0%	0	0 / 0	100%	29.76	1 / 1
adipose	100%	2349.55	1203 / 1204	0%	0	0 / 0
heart	99%	8250.13	849 / 861	0%	0	0 / 0
spleen	98%	1457.94	236 / 241	0%	0	0 / 0
blood vessel	97%	1423.80	1297 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	93%	29.89	74 / 80
peripheral blood	38%	324.72	352 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006446	Biological process	regulation of translational initiation
GO_0016020	Cellular component	membrane
GO_0005737	Cellular component	cytoplasm
GO_0045296	Molecular function	cadherin binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	BZW2
Protein name	Basic leucine zipper and W2 domains 2 eIF5-mimic protein 1 (Basic leucine zipper and W2 domain-containing protein 2)
Synonyms	hCG_19293 HSPC028 5MP1 MSTP017
Description	FUNCTION: Translation initiation regulator which represses non-AUG initiated translation and repeat-associated non-AUG (RAN) initiated translation by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function . Increases the accuracy of translation initiation by impeding EIF5-dependent translation from non-AUG codons by competing with it for interaction with EIF2S2 within the 43S pre-initiation complex (PIC) in an EIF3C-binding dependent manner . .
Accessions	ENST00000405202.5 ENST00000415365.5 ENST00000407633.1 ENST00000437745.5 E9PFE3 ENST00000258761.8 [Q9Y6E2-1] E7EMS9 E9PFD4 C9JF98 ENST00000430000.1 E7ETZ4 F8WDX8 Q9Y6E2 ENST00000436868.5 B5MCE7 Q75MG1 ENST00000433922.6 [Q9Y6E2-1] ENST00000630952.2 ENST00000438834.5 ENST00000446596.5 B5MCH7

BZW2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review