APOL6 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	26 studies	25% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	31% ± 10%	Explore
regulatory T cell	14 studies	19% ± 3%	Explore
CD8-positive, alpha-beta T cell	12 studies	24% ± 9%	Explore
mature NK T cell	11 studies	22% ± 8%	Explore
gamma-delta T cell	11 studies	21% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	23% ± 4%	Explore
adipocyte	10 studies	32% ± 7%	Explore
T cell	9 studies	22% ± 10%	Explore
non-classical monocyte	9 studies	27% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	23% ± 4%	Explore
classical monocyte	8 studies	23% ± 10%	Explore
CD4-positive, alpha-beta T cell	8 studies	19% ± 5%	Explore
macrophage	7 studies	21% ± 3%	Explore
monocyte	7 studies	23% ± 6%	Explore
endothelial cell	6 studies	20% ± 3%	Explore
ciliated cell	6 studies	22% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	22% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	19% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	20% ± 3%	Explore
goblet cell	5 studies	20% ± 4%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	21% ± 2%	Explore
exhausted T cell	4 studies	24% ± 12%	Explore
epithelial cell	4 studies	33% ± 10%	Explore
alveolar macrophage	4 studies	23% ± 4%	Explore
mucosal invariant T cell	4 studies	19% ± 2%	Explore
fibroblast	3 studies	28% ± 12%	Explore
type I pneumocyte	3 studies	23% ± 3%	Explore
respiratory goblet cell	3 studies	24% ± 3%	Explore
squamous epithelial cell	3 studies	38% ± 24%	Explore
leukocyte	3 studies	21% ± 2%	Explore
conventional dendritic cell	3 studies	20% ± 2%	Explore
capillary endothelial cell	3 studies	16% ± 0%	Explore
glomerular endothelial cell	3 studies	20% ± 1%	Explore
lymphocyte	3 studies	20% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	20% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	18% ± 2%	Explore
double negative thymocyte	3 studies	21% ± 6%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	9 studies	21% ± 7%	Explore
lung	3 studies	20% ± 6%	Explore
intestine	3 studies	16% ± 1%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2012.03	1443 / 1445	99%	49.48	181 / 183
lung	100%	4531.87	578 / 578	98%	35.15	1132 / 1155
intestine	100%	3324.03	966 / 966	98%	32.39	515 / 527
liver	100%	5462.05	226 / 226	97%	28.88	395 / 406
stomach	99%	1824.98	354 / 359	99%	40.91	282 / 286
breast	100%	5128.06	458 / 459	97%	37.10	1088 / 1118
thymus	100%	3019.42	652 / 653	97%	27.04	586 / 605
kidney	100%	2317.80	89 / 89	95%	30.97	855 / 901
bladder	100%	1810.67	21 / 21	94%	30.45	475 / 504
prostate	100%	2222.16	245 / 245	91%	21.24	457 / 502
uterus	100%	1858.51	170 / 170	88%	29.49	406 / 459
ovary	100%	2668.08	180 / 180	88%	22.12	380 / 430
skin	82%	1668.97	1492 / 1809	84%	29.34	398 / 472
adrenal gland	99%	2634.33	256 / 258	62%	7.46	143 / 230
pancreas	57%	587.24	188 / 328	98%	27.07	174 / 178
brain	55%	604.40	1450 / 2642	77%	12.51	544 / 705
adipose	100%	6757.91	1204 / 1204	0%	0	0 / 0
spleen	100%	4135.17	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	96%	39.33	43 / 45
peripheral blood	94%	2519.28	869 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	93%	25.56	27 / 29
heart	85%	974.73	731 / 861	0%	0	0 / 0
blood vessel	84%	1316.47	1124 / 1335	0%	0	0 / 0
muscle	48%	612.22	387 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	31%	8.84	25 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1