Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 9 studies | 24% ± 5% | |
| natural killer cell | 7 studies | 19% ± 3% | |
| epithelial cell | 6 studies | 31% ± 11% | |
| glutamatergic neuron | 5 studies | 42% ± 21% | |
| CD8-positive, alpha-beta T cell | 5 studies | 17% ± 1% | |
| neuron | 4 studies | 26% ± 6% | |
| CD16-positive, CD56-dim natural killer cell, human | 4 studies | 17% ± 1% | |
| naive B cell | 4 studies | 16% ± 2% | |
| regulatory T cell | 4 studies | 16% ± 1% | |
| astrocyte | 4 studies | 28% ± 5% | |
| macrophage | 4 studies | 19% ± 2% | |
| oligodendrocyte | 4 studies | 23% ± 4% | |
| plasmacytoid dendritic cell | 4 studies | 22% ± 4% | |
| gamma-delta T cell | 4 studies | 21% ± 8% | |
| hematopoietic precursor cell | 3 studies | 18% ± 2% | |
| microglial cell | 3 studies | 21% ± 3% | |
| mucosal invariant T cell | 3 studies | 21% ± 2% | |
| pericyte | 3 studies | 19% ± 2% | |
| precursor B cell | 3 studies | 18% ± 1% | |
| ciliated cell | 3 studies | 23% ± 5% | |
| GABAergic neuron | 3 studies | 43% ± 6% | |
| oligodendrocyte precursor cell | 3 studies | 27% ± 5% | |
| dendritic cell | 3 studies | 26% ± 6% | |
| abnormal cell | 3 studies | 22% ± 5% | |
| basal cell | 3 studies | 29% ± 6% | |
| goblet cell | 3 studies | 27% ± 6% | |
| interneuron | 3 studies | 36% ± 18% | |
| double negative thymocyte | 3 studies | 21% ± 5% | |
| CD4-positive, alpha-beta T cell | 3 studies | 19% ± 2% | |
| T cell | 3 studies | 16% ± 0% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 4504.92 | 459 / 459 | 100% | 86.04 | 1118 / 1118 |
| esophagus | 100% | 4669.32 | 1445 / 1445 | 100% | 88.93 | 183 / 183 |
| liver | 100% | 3231.24 | 226 / 226 | 100% | 34.86 | 406 / 406 |
| ovary | 100% | 3922.37 | 180 / 180 | 100% | 63.96 | 430 / 430 |
| pancreas | 100% | 2882.45 | 328 / 328 | 100% | 50.06 | 178 / 178 |
| prostate | 100% | 4224.79 | 245 / 245 | 100% | 63.25 | 502 / 502 |
| uterus | 100% | 4954.46 | 170 / 170 | 100% | 64.08 | 459 / 459 |
| brain | 100% | 4115.40 | 2640 / 2642 | 100% | 62.72 | 705 / 705 |
| thymus | 100% | 4422.88 | 653 / 653 | 100% | 67.42 | 604 / 605 |
| lung | 100% | 3979.46 | 577 / 578 | 100% | 71.74 | 1155 / 1155 |
| kidney | 100% | 3681.60 | 89 / 89 | 100% | 49.63 | 899 / 901 |
| stomach | 100% | 3711.02 | 359 / 359 | 100% | 71.73 | 285 / 286 |
| bladder | 100% | 4595.14 | 21 / 21 | 100% | 57.37 | 502 / 504 |
| intestine | 100% | 4850.45 | 966 / 966 | 99% | 70.35 | 524 / 527 |
| skin | 100% | 5508.05 | 1809 / 1809 | 98% | 57.49 | 461 / 472 |
| adrenal gland | 100% | 4154.26 | 258 / 258 | 96% | 32.20 | 221 / 230 |
| adipose | 100% | 4342.42 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 4739.09 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 70.62 | 29 / 29 |
| muscle | 100% | 3278.59 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4223.43 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 76.40 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.16 | 1 / 1 |
| heart | 97% | 2035.43 | 832 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 91% | 29.12 | 73 / 80 |
| peripheral blood | 82% | 3034.89 | 765 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_0044346 | Biological process | fibroblast apoptotic process |
| GO_2000270 | Biological process | negative regulation of fibroblast apoptotic process |
| GO_0016607 | Cellular component | nuclear speck |
| GO_0005681 | Cellular component | spliceosomal complex |
| GO_0016020 | Cellular component | membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0017134 | Molecular function | fibroblast growth factor binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | API5 |
| Protein name | Apoptosis inhibitor 5 (API-5) (Antiapoptosis clone 11 protein) (AAC-11) (Cell migration-inducing gene 8 protein) (Fibroblast growth factor 2-interacting factor) (FIF) (Protein XAGL) Apoptosis inhibitor 5 |
| Synonyms | MIG8 |
| Description | FUNCTION: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. . |
| Accessions | E9PQK6 ENST00000420461.6 [Q9BZZ5-5] Q9BZZ5 ENST00000531273.6 [Q9BZZ5-4] ENST00000378852.7 [Q9BZZ5-2] ENST00000455725.6 [Q9BZZ5-6] H0YER7 ENST00000534600.5 [Q9BZZ5-1] ENST00000526394.1 ENST00000534695.5 |