ADNP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0044849Biological processestrous cycle
GO_0019934Biological processcGMP-mediated signaling
GO_0010468Biological processregulation of gene expression
GO_0045773Biological processpositive regulation of axon extension
GO_0010976Biological processpositive regulation of neuron projection development
GO_0010629Biological processnegative regulation of gene expression
GO_0090263Biological processpositive regulation of canonical Wnt signaling pathway
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0050805Biological processnegative regulation of synaptic transmission
GO_0051402Biological processneuron apoptotic process
GO_0001933Biological processnegative regulation of protein phosphorylation
GO_0030182Biological processneuron differentiation
GO_0033484Biological processintracellular nitric oxide homeostasis
GO_0050731Biological processpositive regulation of peptidyl-tyrosine phosphorylation
GO_0009743Biological processresponse to carbohydrate
GO_0043524Biological processnegative regulation of neuron apoptotic process
GO_0051965Biological processpositive regulation of synapse assembly
GO_0007614Biological processshort-term memory
GO_0005615Cellular componentextracellular space
GO_0043025Cellular componentneuronal cell body
GO_0030425Cellular componentdendrite
GO_0090575Cellular componentRNA polymerase II transcription regulator complex
GO_0030424Cellular componentaxon
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0048487Molecular functionbeta-tubulin binding
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0003682Molecular functionchromatin binding
GO_0042277Molecular functionpeptide binding
GO_0008013Molecular functionbeta-catenin binding
GO_0005507Molecular functioncopper ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameADNP
Protein nameActivity dependent neuroprotector homeobox
Activity-dependent neuroprotector homeobox protein (Activity-dependent neuroprotective protein)
Activity-dependent neuroprotector homeobox
SynonymsKIAA0784
ADNP1
DescriptionFUNCTION: May be involved in transcriptional regulation. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation. Positively modulates WNT-beta-catenin/CTNN1B signaling, acting by regulating phosphorylation of, and thereby stabilizing, CTNNB1. May be required for neural induction and neuronal differentiation. May be involved in erythroid differentiation (By similarity). .

AccessionsA0A2R8YCL6
ENST00000645081.1
Q6DHZ8
ENST00000349014.8
ENST00000396029.8
Q9H2P0
ENST00000621696.5
ENST00000673732.1
A0A669KBJ7
ENST00000371602.9
A0A2R8Y6X0
ENST00000644386.1
ENST00000396032.8