GO_1990806 | ligand-gated ion channel signaling pathway | OmnibusX

ligand-gated ion channel signaling pathway

I. Involved cell types

	Genes	Cell types	No. of supported studies
Group 1	FFAR2	neutrophil enterochromaffin-like cell	3 studies
Group 2	PLCB1 GNA11 ITPR1	dopaminergic neuron	5 studies
Group 3	ORAI1	myeloid cell lymphocyte epithelial cell B cell	17 studies
Group 4	F2	hepatocyte	6 studies
Group 5	CHRM3	glutamatergic neuron GABAergic neuron	39 studies

II. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	F2-F2RL2	THRB_HUMAN - PAR3_HUMAN	Ligand-Receptor	Adhesion by Prothrombin

III. Literature review

Name	ligand-gated ion channel signaling pathway
ID	GO_1990806
collection_id	Biological process
Exact synonym	ligand-gated ion channel signalling pathway
Description	The series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription.
External URL
Genes	F2RL2 FFAR1 ORAI1 GNA11 FFAR2 F2 CHRM3 PLCB1 ITPR1