Biological process

ribosome-associated ubiquitin-dependent protein breakdown, ribosome-associated ubiquitin-dependent protein catabolism, ribosome-associated ubiquitin-dependent protein degradation

The chemical reactions and pathways resulting in the breakdown of a protein or peptide encoded by an aberrant message and associated with a stalled ribosome. Degradation is initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the ribosome-associated protein.