Biological process

de novo centriole assembly via deuterosome

Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation.

centriole amplification, deuterosomal basal body biogenesis, deuterosome pathway, deuterosome-mediated centriole biogenesis, multiciliation, multiciliogenesis

In most eukaryotic cells, 'centriole' (GO:0005814) and 'ciliary basal body' (GO:0036064) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component.